Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
11/12/2018	All-cause and cardio-renal-metabolic mortality in people with or without type 2 diabetes: a comparative international trend study
11/12/2018	The Costs and Complications of Colostomy, Ileostomy and Urostomy in England in Primary and Secondary Care: A 10-Year Study using Real World Datasets
11/12/2018	Identifying population groups at risk of avoidable hospitalisations for community acquired pneumonia in the UK.
11/12/2018	Mental illness: changes in incidence, prevalence, treatment and outcomes 2000-2018
14/12/2018	Patient characteristic and treatment pattern for uncontrolled adult type 1 diabetes patients: a cross-sectional analysis to support economic modelling activities in a UK-specific context
14/12/2018	Translation of the electronic Frailty Index for use with the International Statistical Classification of Diseases and Related Health Problems tool in hip and knee replacement patients
14/12/2018	Low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride and diverse non-cardiovascular diseases: a population-based cohort study of England using linkage dataset
17/12/2018	Linaclotide Safety Study for the Assessment of Diarrhoea - Complications and Associated Risk Factors in the UK population with IBS-C
19/12/2018	The progression of key clinical parameters in adult diabetes patients (selected type 1 and type 2 diabetes sub-population): a retrospective cohort analysis to support economic modelling activities in a UK-specific context
19/12/2018	Understanding the predictive values of symptoms, prescriptions, and investigation patterns for cancer and non-neoplastic disease in primary care consultees
19/12/2018	Identifying risk factors associated with having a stroke following an acute exacerbation of COPD (AECOPD)
19/12/2018	A study using Observational Health Data Sciences and Informatics tools to characterize treatment pathways for stroke prevention in Atrial Fibrillation across diverse population settings (TxPath-AF)
19/12/2018	A personalized dynamic blood pressure control plan for patients with hypertension to maximize the delay of cardiovascular events
19/12/2018	Testing a data-based definition of severity in atopic dermatitis in a linked primary and secondary care dataset in England: Implications on clinical outcomes and healthcare resource use
19/12/2018	The Health Economic Burden of Atopic Dermatitis and Associated Dermatologic Conditions: A Study of Cow's Milk Allergy (CMA) in patients > 5 years of age in the Primary and Secondary Care Pathways
19/12/2018	Withdrawal of historical inhaled corticosteroids in primary care using electronic records
21/12/2018	The pattern of incident fractures in patients with diabetes mellitus compared to matched controls
21/12/2018	Clinical features of giant cell arteritis (GCA): An observational study using linked electronic primary and secondary care medical records
21/12/2018	Defining different recovery trajectories following acute infections as a measure of frailty
02/01/2019	BurDeN Study: Incidence and Burden of Disease from Shingles and Post-Herpetic Neuralgia in the over 80 year olds in the UK