Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort descending Title
14/12/2018 Translation of the electronic Frailty Index for use with the International Statistical Classification of Diseases and Related Health Problems tool in hip and knee replacement patients
14/12/2018 Low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride and diverse non-cardiovascular diseases: a population-based cohort study of England using linkage dataset
17/12/2018 Linaclotide Safety Study for the Assessment of Diarrhoea - Complications and Associated Risk Factors in the UK population with IBS-C
19/12/2018 Testing a data-based definition of severity in atopic dermatitis in a linked primary and secondary care dataset in England: Implications on clinical outcomes and healthcare resource use
19/12/2018 A study using Observational Health Data Sciences and Informatics tools to characterize treatment pathways for stroke prevention in Atrial Fibrillation across diverse population settings (TxPath-AF)
19/12/2018 The progression of key clinical parameters in adult diabetes patients (selected type 1 and type 2 diabetes sub-population): a retrospective cohort analysis to support economic modelling activities in a UK-specific context
19/12/2018 Identifying risk factors associated with having a stroke following an acute exacerbation of COPD (AECOPD)
19/12/2018 The Health Economic Burden of Atopic Dermatitis and Associated Dermatologic Conditions: A Study of Cow's Milk Allergy (CMA) in patients > 5 years of age in the Primary and Secondary Care Pathways
19/12/2018 Withdrawal of historical inhaled corticosteroids in primary care using electronic records
19/12/2018 Understanding the predictive values of symptoms, prescriptions, and investigation patterns for cancer and non-neoplastic disease in primary care consultees
19/12/2018 A personalized dynamic blood pressure control plan for patients with hypertension to maximize the delay of cardiovascular events
21/12/2018 Defining different recovery trajectories following acute infections as a measure of frailty
21/12/2018 Clinical features of giant cell arteritis (GCA): An observational study using linked electronic primary and secondary care medical records
21/12/2018 The pattern of incident fractures in patients with diabetes mellitus compared to matched controls
02/01/2019 An epidemiological study to compare adverse events associated with different formulations of latanoprost
02/01/2019 BurDeN Study: Incidence and Burden of Disease from Shingles and Post-Herpetic Neuralgia in the over 80 year olds in the UK
10/01/2019 Understanding the Relationship between Multimorbidity in Later Life, Use of Health Services and Costs of Health Care (MuSeCol)
10/01/2019 The influence of the number of concomitant drugs used, on the safety and efficacy of NOACs compared to warfarin in patients with atrial fibrillation treated in routine care
10/01/2019 Guideline discordant diagnostic care: when do primary care referrals not reflect guidelines for suspected cancer?
10/01/2019 Are beta blockers beneficial or harmful in obstructive sleep apnoea?