Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
09/06/2021	Cost-effectiveness of osteoporotic fracture risk assessment in people with intellectual disabilities
10/06/2021	Does ethnicity affect the recognition of palliative care needs? An observational retrospective cohort study
10/06/2021	Epidemiology of gout, its treatment and comorbidities - a prospective cohort study using data from Clinical Practice Research Datalink (CPRD)
10/06/2021	Prescription of blood pressure lowering and lipid lowering treatment in the UK and New Zealand: a cross sectional study
11/06/2021	Optimal dynamic treatment regimes for the management of chronic obstructive pulmonary disease (COPD)
15/06/2021	Mortality rates, risk factors and treatment patterns in patients diagnosed with moderate-to-very-severe chronic obstructive pulmonary disease in England: a retrospective observational study using CPRD data
17/06/2021	TRial to Assess Implementation of New research in a primary care Setting (TRAINS): a pragmatic cluster randomised controlled trial of an educational intervention to promote prescription uptake in General Practitioner Practices
21/06/2021	Incident Neutropenia in New Users of Cyclooxygenase-Inhibitors: An Observational Cohort Study
21/06/2021	Demographic, socioeconomic, temporal, and spatial patterns in the prescription of contraceptives within UK primary care
24/06/2021	Identifying how best to identify pneumonia and differentiate pneumonia from asthma and chronic obstructive pulmonary disease exacerbations in routine primary care data
28/06/2021	Trends in remote GP consultations and the impact of remote consultations on antibiotic prescribing of antibiotics pre- and during COVID - an observational study
28/06/2021	Living with dementia: understanding the prevalence of young-onset dementia
28/06/2021	Event Rates and Risk Factors for Cardiovascular Events in a Population with an Acute Coronary Syndrome Hospitalization in the United Kingdom
01/07/2021	Development of a Pregnancy Register in the CPRD Aurum database.
01/07/2021	Antipsychotics and risk of falls in people with Alzheimer's Disease and agitation. A self-controlled case series study and cohort study
01/07/2021	Socio-economic inequalities in prevalence and management of long-term conditions in primary care: a descriptive study
05/07/2021	Estimating national and local prevalence of mental health conditions during perinatal period in England: an exploratory study
06/07/2021	Age-specific mortality rates of males diagnosed with Duchenne Muscular Dystrophy.
07/07/2021	The effect of increasing physician workload on the choice of referrals to secondary care units and lab tests
09/07/2021	Trends in primary care prescribing of benzodiazepines, antipsychotics and beta-blockers for anxiety.