Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
28/03/2023	Descriptive analysis of primary care demand in England
28/03/2023	Prescribing of allopurinol among different ethnic groups: feasibility for a genetic study.
28/03/2023	Use of menopausal hormone therapy and risk of fractures: nested case-control study using CPRD
28/03/2023	A longitudinal analysis investigating cardiovascular outcomes in people with type 2 diabetes by treatment class in England.
27/03/2023	CHARIOT: A Cardiovascular Health Assessment and Risk-based Intervention Optimisation Tool embedded within the patient-facing health record
27/03/2023	Management of contraception after pregnancy by primary care in England
27/03/2023	Evaluation of ethnicity recording and ascertainment methods using linked data from the UKs Clinical Practice Research Datalink and Hospital Episode Statistics
27/03/2023	Development and validation of Rheumatoid Arthritis PredIction moDel using primary care health records (RAPID)
23/03/2023	Dipeptidyl peptidase-4 inhibitors and the risk of gallbladder and bile duct diseases among patients with type 2 diabetes
23/03/2023	Treatment Patterns, Healthcare Resource Utilization and Costs in Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in England
23/03/2023	Feasibility study on data availability of early life factors associated with asthma.
23/03/2023	Multi-morbidity, Inequality and Use of and Access to Health Care (MICA)
21/03/2023	Gabapentinoid Use and the Risk of Fractures in Patients with Inflammatory Arthritis: a nested Case-Control Study in the Clinical Practice Research Datalink Aurum.
14/03/2023	Blood pressure and adverse cardiovascular outcomes in older people with chronic kidney disease and type 2 diabetes
14/03/2023	Clinical implications of intentional weight loss in patients with type 2 diabetes (T2D): a retrospective cohort study using the UK Clinical Practice Research Datalink (CPRD) Aurum database
13/03/2023	Epidemiology and burden of imminent subsequent fractures in postmenopausal women
13/03/2023	The epidemiology, demographics and socio-economic aspects of patients with myasthenia gravis and Lambert-eaton syndrome.
13/03/2023	Improving management of non-alarm symptoms of bladder and kidney cancer: a case-control study and health economic assessment
06/03/2023	Associations of clusters of adults with multimorbidity with clinical outcomes and healthcare utilisation
06/03/2023	Demographic groups and prodromal symptoms in rheumatoid arthritis (RA) in primary care: An analysis to support health equity in big-data clinical prediction models.