Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort descending Title
13/06/2016 Descriptive assessment of the Hospital Treatment Insights database and its link to the Clinical Practice Research Datalink for research on antibiotic dispensing in English hospitals
13/06/2016 Use of parenteral corticosteroids and risk of type 2 diabetes mellitus.
15/06/2016 The association between bariatric surgery and renal outcomes
15/06/2016 Oral anticoagulants for atrial fibrillation and the risk of fractures
20/06/2016 What is the occurrence of clinically diagnosed coeliac disease and dermatitis herpetiformis in the UK today? A population based cohort study utilising electronically linked health records.
20/06/2016 Three months versus 28 day prescriptions: a retrospective analysis of CPRD data to determine differences in the cost of drug wastage, dispensing fees and prescriber time
20/06/2016 Diabetes, use of metformin and the risk of meningioma
21/06/2016 Immunosuppressive therapy and Parkinson's disease risk
28/06/2016 Comparative effectiveness of lansoprazole and omeprazole for the prevention of gastrointestinal bleeding and malignancy
28/06/2016 Pharmacoepidemiology of pancreatin use in non-cystic fibrosis patients and comparison of all-cause mortality with that of their matched controls
28/06/2016 Generalizability of Clinical Trial Results: Value of Individual Data versus Aggregate Data
28/06/2016 Characterisation and cardiovascular risk profile of type 2 diabetes mellitus patients according to initiation of antidiabetic medications
28/06/2016 Long-term severe non-dermatological outcomes in eczema
28/06/2016 Eligibility for Lung volume reduction surgery for COPD in the UK
29/06/2016 Assessment of Metformin Use Pattern in UK using CPRD
03/07/2016 Safety study to quantify the risk of ulceration (including all sites of occurrence), and related events (including perforations, fistula, abscess and bleeding) and death among patients treated with nicorandil with and without diverticular disease
04/07/2016 Statin use and incident hand osteoarthritis: A propensity-score matched sequential cohort study
04/07/2016 Androgen Deprivation Therapy and Risk of Dementia
04/07/2016 Patient Characteristics Associated With Initiation Of Insulin Glargine Among Patients With Type 1 Or Type 2 Diabetes Mellitus In The United Kingdom
04/07/2016 Risk of stroke following discontinuation of oral anticoagulant treatment for atrial fibrillation: a cohort study