2021 |
Characterising the background incidence rates of adverse events of special interest for covid-19 vaccines in eight countries: multinational network cohort study
10.1136/bmj.n1435
Authors: X. Li, A. Ostropolets, R. Makadia, A. Shoaibi, A. Rao, A. Sena, E. Martinez-Hernandez, K. Verhamme, P. Rijnbeek, P.B. Ryan, D. Prieto-Alhambra |
2021 |
Characterization and Associated Costs of Constipation Relating to Exposure to Strong Opioids in England: An Observational Study
10.1016/j.clinthera.2021.03.021
Authors: C. Morgan, S. Jenkins-Jones, R. Knaggs, C. Currie, P. Conway, C. Poole, E. Berni |
2021 |
Clinical features and diagnosis of multiple myeloma: a population-based cohort study in primary care
10.1136/bmjopen-2021-052759
Authors: A. Seesaghur, N. Petruski-Ivleva, V. Banks, J. Wang, A. Abbasi, D. Neasham, K. Ramasamy |
2021 |
Clinical prediction tools to identify patients at highest risk of myeloma in primary care: a retrospective open cohort study
10.3399/bjgp.2020.0697
Authors: C. Koshiaris, A. Van den Bruel, B. Nicholson, S. Lay-Flurrie, F. Hobbs, J. Oke |
2021 |
A Cohort Study to Evaluate the Risk of Hospitalisation for Congestive Heart Failure Associated with the Use of Aclidinium and Other Chronic Obstructive Pulmonary Disease Medications in the UK Clinical Practice Research Datalink
10.2147/copd.s301624
Authors: C. Rebordosa, E. Plana, A. Rubino, J. Aguado, A. Lei, S. Daoud, N. Saigi-Morgui, S. Perez-Gutthann, E. Rivero-Ferrer |
2021 |
Comorbid diseases and conditions in people with HIV in the UK
10.1080/03007995.2021.2003671
Authors: B. Jones, A. Freedman, M. Thomas, C. Villalba-Mendez, L. Sathia, D. Flanagan, S. Francis, C. Currie |
2021 |
Comparative differences in musculoskeletal pain consultation and analgesic prescription for people with dementia: a UK-wide matched cohort study
10.1097/j.pain.0000000000002257
Authors: L. Bullock, J. Bedson, Y. Chen, C. Chew-Graham, P. Campbell |
2021 |
Comparative Effectiveness of Initial LAMA versus LABA in COPD: Real-World Cohort Study
10.1080/15412555.2021.1877649
Authors: S. Suissa, S. Dell'Aniello, P. Ernst |
2021 |
Comparing initial LABA-ICS inhalers in COPD: Real-world effectiveness and safety
10.1016/j.rmed.2021.106645
Authors: S. Suissa, S. Dell'Aniello, P. Ernst |
2021 |
Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort
10.1001/jamanetworkopen.2021.5329
Authors: C. Dormuth, B. Winquist, A. Fisher, F. Wu, P. Reynier, S. Suissa, M. Dahl, Z. Ma, X. Lu, J. Zhang, C. Raymond, K. Filion, R. Platt, C. Moriello, J. Paterson |
2021 |
The Complex Association Between Bariatric Surgery and Depression: a National Nested-Control Study
10.1007/s11695-020-05201-z
Authors: C. Arhi, R. Dudley, O. Moussa, M. Ardissino, S. Scholtz, S. Purkayastha |
2021 |
Concordance and timing in recording cancer events in primary care, hospital and mortality records for patients with and without psoriasis: A population-based cohort study
10.1371/journal.pone.0254661
Authors: A. Trafford, R. Parisi, M. Rutter, E. Kontopantelis, C. Griffiths, D. Ashcroft |
2021 |
Concordance with urgent referral guidelines in patients presenting with any of six \textquoterightalarm\textquoteright features of possible cancer: a retrospective cohort study using linked primary care records
10.1136/bmjqs-2021-013425
Authors: B. Wiering, G. Lyratzopoulos, W. Hamilton, J. Campbell, G. Abel |
2021 |
Consistency of ranking was evaluated as new measure for prediction model stability: longitudinal cohort study
10.1016/j.jclinepi.2021.06.026
Authors: Y. Li, M. Sperrin, D. Ashcroft, T. van Staa |
2021 |
Consultation patterns and frequent attenders in UK primary care from 2000 to 2019: a retrospective cohort analysis of consultation events across 845 general practices
10.1136/bmjopen-2021-054666
Authors: E. Kontopantelis, M. Panagioti, T. Farragher, L. Munford, R. Parisi, C. Planner, S. Spooner, A. Tse, D. Ashcroft, A. Esmail |
2021 |
Current treatments used in clinical practice for major depressive disorder and treatment resistant depression in England: A retrospective database study
10.1016/j.jpsychires.2021.05.026
Authors: T. Denee, C. Kerr, T. Ming, R. Wood, T. Tritton, C. Middleton-Dalby, O. Massey, M. Desai |
2021 |
Data-driven identification of ageing-related diseases from electronic health records
10.1038/s41598-021-82459-y
Authors: V. Kuan, H. Fraser, M. Hingorani, S. Denaxas, A. Gonzalez-Izquierdo, K. Direk, D. Nitsch, R. Mathur, C. Parisinos, R. Lumbers, R. Sofat, I. Wong, J. Casas, J. Thornton, H. Hemingway, L. Partridge, A. Hingorani |
2021 |
Defining Clinically-Relevant Target Populations Using Real-World Data to Guide the Design of Representative Antidiabetic Drug Trials
10.1002/cpt.2213
Authors: R. Pradhan, D. Abrahami, H. Yin, O. H. Y. Yu, V. Sahasrabudhe, Baumfeld Andre, L. Azoulay |
2021 |
Detecting undiagnosed atrial fibrillation in UK primary care: Validation of a machine learning prediction algorithm in a retrospective cohort study
10.1177/2047487320942338
Authors: S. Sekelj, B. Sandler, E. Johnston, K. Pollock, N. Hill, J. Gordon, C. Tsang, S. Khan, F. Ng, U. Farooqui |
2021 |
"Determinants of treatment modification before and after implementation of the updated 2015 NICE guideline on type 2 diabetes: a retrospective cohort study"
10.1016/j.diabres.2021.108828
Authors: J. van Dalem, Cgj Brouwers, A. Burden, D. C, O. Klungel, F. de Vries, Hm Driessen |
2021 |
Determining propensity for sub-optimal low-density lipoprotein cholesterol response to statins and future risk of cardiovascular disease
10.1371/journal.pone.0260839
Authors: S. Weng, R. Akyea, K. Man, W. C. Y. Lau, B. Iyen, J. Blais, E. Chan, C. Siu, N. Qureshi, I. Wong, J. Kai |
2021 |
Development and Validation of a Primary Care Electronic Health Record Phenotype to Study Migration and Health in the UK
10.3390/ijerph182413304
Authors: N. Pathak, C. Zhang, Y. Boukari, R. Burns, R. Mathur, A. Gonzalez-Izquierdo, S. Denaxas, P. Sonnenberg, A. Hayward, R. Aldridge |
2021 |
Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood-tests during long-term treatment: cohort study using data from Clinical Practice Research Datalink Gold and Aurum
10.1093/rheumatology/keab790
Authors: G. Nakafero, M. Grainge, T. Card, M. Taal, G. Aithal, W. Zhang, M. Doherty, C. Fox, C. Mallen, A. Abhishek |
2021 |
Disease severity, flares and treatment patterns in adults with systemic lupus erythematosus in the UK: a real-world observational retrospective cohort analysis
10.1093/rap/rkab061
Authors: J. Langham, V. Barut, M. Samnaliev, S. Langham, S. Weir, X. Wang, B. Desta, E. Hammond |
2021 |
Dupuytren\textquoterights Disease Predicts Increased All-Cause and Cancer-Specific Mortality: Analysis of a Large Cohort from the U.K. Clinical Practice Research Datalink
10.1097/prs.0000000000007825
Authors: O. Olaiya, M. Huynh |
2021 |
Effect of competing mortality risks on predictive performance of the QRISK3 cardiovascular risk prediction tool in older people and those with comorbidity: external validation population cohort study
10.1016/s2666-7568(21)00088-x
Authors: S. Livingstone, D. Morales, P. Donnan, K. Payne, A. Thompson, J. Youn, B. Guthrie |
2021 |
Effectiveness of "Priorix" Against Measles and Mumps Diseases in Children Born After 2004 in the United Kingdom: A Retrospective Case-control Study Using the Clinical Practice Research Datalink GOLD Database
10.1097/inf.0000000000003111
Authors: M. Povey, E. Aris, B. Cheuvart, G. Hall, C. Cohet, C. Willame |
2021 |
Effectiveness of risk minimisation measures for valproate: a drug utilisation study based on implementation of a Risk Minimisation Programme in Europe, analysis of data from the UK
10.1080/03007995.2021.1997286
Authors: B. Ehlken, C. Nishikawa, S. Kaplan, I. Dresco, D. Granados, M. Toussi |
2021 |
Effects of the COVID-19 pandemic on primary care-recorded mental illness and self-harm episodes in the UK: a population-based cohort study
10.1016/s2468-2667(20)30288-7
Authors: M. Carr, S. Steeg, R. Webb, N. Kapur, C. Chew-Graham, K. Abel, H. Hope, M. Pierce, D. Ashcroft |
2021 |
Endocrine therapy use and cardiovascular risk in postmenopausal breast cancer survivors
10.1136/heartjnl-2020-317510
Authors: A. Matthews, Peacock Hinton, S. Stanway, A. Lyon, L. Smeeth, J. Lund, K. Bhaskaran |
2021 |
Epidemiology of Distal Renal Tubular Acidosis: A Study Using Linked UK Primary Care and Hospital Data
10.1159/000516876
Authors: F. Bianic, F. Guelfucci, L. Robin, C. Martre, D. Game, D. Bockenhauer |
2021 |
Epidemiology of skin event rates among users of pumps for the subcutaneous administration of drugs for chronic conditions
10.1080/03007995.2021.1953971
Authors: S. Jick, D. Oleske, R. Persson, J. Zamudio, M. Facheris |
2021 |
Epilepsy and mortality: a retrospective cohort analysis with a nested case-control study identifying causes and risk factors from primary care and linkage-derived data
10.1136/bmjopen-2021-052841
Authors: G. Wojewodka, M. Gulliford, M. Ashworth, M. Richardson, L. Ridsdale |
2021 |
Estimating the population health burden of musculoskeletal conditions using primary care electronic health records
10.1093/rheumatology/keab109
Authors: D. Yu, G. Peat, K. Jordan, J. Bailey, D. Prieto-Alhambra, D. Robinson, V . Y. Strauss, K. Walker-Bone, A. Silman, M. Mamas, S. Blackburn, S. Dent, K. Dunn, A. Judge, J. Protheroe, R. Wilkie |
2021 |
Estimation of Risk of Death Attributable to Acute Gastroenteritis Not Caused by Clostridioides difficile Infection Among Hospitalized Adults in England
10.2147/clep.s296516
Authors: M. Alexandridou, T. Cattaert, T. Verstraeten |
2021 |
Estimation of the increased risk associated with recurrent events or polyvascular atherosclerotic cardiovascular disease in the United Kingdom
10.1177/2047487319899212
Authors: M. Danese, P. Pemberton-Ross, D. Catterick, G. Villa |
2021 |
Ethnic differences in the incidence of clinically diagnosed influenza: an England population-based cohort study 2008-2018
10.12688/wellcomeopenres.16620.3
Authors: J. Davidson, A. Banerjee, R. Mathur, M. Ramsay, L. Smeeth, J. Walker, H. McDonald, C. Warren-Gash |
2021 |
Ethnic, social and multimorbidity disparities in therapeutic inertia: a UK primary care observational study in patients newly diagnosed with type 2 diabetes
10.1111/dom.14482
Authors: Y. Chudasama, F. Zaccardi, B. Coles, C. Gillies, C. Hvid, S. Seidu, M. Davies, K. Khunti |
2021 |
Ethnicity-specific BMI cutoffs for obesity based on type 2 diabetes risk in England: a population-based cohort study
10.1016/s2213-8587(21)00088-7
Authors: R. Caleyachetty, T. Barber, N. Mohammed, F. Cappuccio, R. Hardy, R. Mathur, A. Banerjee, P. Gill |
2021 |
Evaluating a Cox marginal structural model to assess the comparative effectiveness of inhaled corticosteroids versus no inhaled corticosteroid treatment in chronic obstructive pulmonary disease
10.1016/j.annepidem.2021.11.004
Authors: C. Cabrera, C. Quelen, M. Ouwens, K. Hedman, U. Rigney, J. Quint |
2021 |
Evaluating the safety of mental health-related prescribing in UK primary care: a cross-sectional study using the Clinical Practice Research Datalink (CPRD)
10.1136/bmjqs-2021-013427
Authors: W . Y. Khawagi, D. Steinke, M. Carr, A. Wright, D. Ashcroft, A. Avery, R. Keers |
2021 |
Evidence of disparities in the provision of the maternal postpartum 6-week check in primary care in England, 2015-2018: an observational study using the Clinical Practice Research Datalink (CPRD)
10.1136/jech-2021-216640
Authors: Y. Li, J. Kurinczuk, C. Gale, D. Siassakos, C. Carson |
2021 |
Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic
10.1093/eurjpc/zwaa155
Authors: A. Banerjee, S. Chen, L. Pasea, A. Lai, M. Katsoulis, S. Denaxas, V. Nafilyan, B. Williams, W. Wong, A. Bakhai, K. Khunti, D. Pillay, M. Noursadeghi, H. Wu, N. Pareek, D. Bromage, T. McDonagh, J. Byrne, J. Teo, A. Shah, B. Humberstone, L. Tang, A. Shah, A. Rubboli, Y. Guo, Y. Hu, C. Sudlow, G. Lip, H. Hemingway |
2021 |
Factors associated with potentially missed acute deterioration in primary care
10.3399/bjgp.2020.0986
Authors: E. Cecil, A. Bottle, A. Majeed, P. Aylin |
2021 |
The financial burden of treating patients presenting with acute and chronic cough
10.1080/03007995.2021.1982685
Authors: S. Birring, C. Currie, S. Holden, S. Jenkins-Jones, E. Berni, B. Jones, T. Berni, H. Langerman |
2021 |
Full Mortality risk in patients with adrenal insufficiency using Prednisolone or Hydrocortisone: A Retrospective Cohort study
10.1210/clinem/dgab347
Authors: K. Ngaosuwan, D. Johnston, I. Godsland, J. Cox, A. Majeed, J. Quint, N. Oliver, S. Robinson |
2021 |
Glucose Control, Sulfonylureas, and Insulin Treatment in Elderly People With Type 2 Diabetes and Risk of Severe Hypoglycemia and Death: An Observational Study
10.2337/dc20-0876
Authors: S. Ling, F. Zaccardi, C. Lawson, S. Seidu, M. Davies, K. Khunti |
2021 |
Glycemic Control, Diabetic Complications, and Risk of Dementia in Patients With Diabetes: Results From a Large U.K. Cohort Study
10.2337/dc20-2850
Authors: B. Zheng, B. Su, G. Price, I. Tzoulaki, S. Ahmadi-Abhari, L. Middleton |
2021 |
GP consultation rates for sequelae after acute covid-19 in patients managed in the community or hospital in the UK: population based study
10.1136/bmj-2021-065834
Authors: H. Whittaker, C. Gulea, A. Koteci, C. Kallis, A. Morgan, C. Iwundu, M. Weeks, R. Gupta, J. Quint |
2021 |
Guideline interval: A new time interval in the diagnostic pathway for symptomatic cancer
10.1016/j.canep.2021.101969
Authors: S. Price, G. Abel, W. Hamilton |