Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 April 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 5MB, 226 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 20 results:
Author Title [ Type(Desc)] Year
Filters: Author is Mallen, C.  [Clear All Filters]
Journal Article
A. A. Sultan, Mallen, C., Muller, S., Hider, S., Scott, I., Helliwell, T., and Hall, L. J., Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study, BMC Med, vol. 17, p. 154, 2019.
C. F. Kuo, Grainge, M. J., Mallen, C., Zhang, W., and Doherty, M., Comorbidities in patients with gout prior to and following diagnosis: case-control study, Ann Rheum Dis, vol. 75, pp. 210-7, 2016.
M. Nowakowska, Zghebi, S. S., Ashcroft, D. M., Buchan, I., Chew-Graham, C., Holt, T., Mallen, C., van Marwijk, H., Peek, N., Perera-Salazar, R., Reeves, D., Rutter, M. K., Weng, S. F., Qureshi, N., Mamas, M. A., and Kontopantelis, E., The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort, BMC Med, vol. 17, p. 145, 2019.
G. Nakafero, Grainge, M., Valdes, A., Townsend, N., Mallen, C., Zhang, W., Doherty, M., Mamas, M. A., and Abhishek, A., Do beta-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink, BMJ Open, vol. 9, p. e032050, 2019.
C. F. Kuo, Grainge, M. J., Mallen, C., Zhang, W., and Doherty, M., Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score-matched landmark analysis, Rheumatology (Oxford), vol. 54, pp. 2145-50, 2015.
A. A. Sultan, Mallen, C., Hayward, R., Muller, S., Whittle, R., Hotston, M., and Roddy, E., Gout and subsequent erectile dysfunction: a population-based cohort study from England, Arthritis Res Ther, vol. 19, p. 123, 2017.
S. L. Lay-Flurrie, Sheppard, J. P., Stevens, R. J., Mallen, C., Heneghan, C., Hobbs, F. R., Williams, B., Mant, J., and McManus, R. J., Impact of changes to national guidelines on hypertension-related workload: an interrupted time series analysis in English primary care, Br J Gen Pract, vol. 71, pp. e296-e302, 2021.
C. F. Kuo, Grainge, M. J., Mallen, C., Zhang, W., and Doherty, M., Impact of gout on the risk of atrial fibrillation, Rheumatology (Oxford), vol. 55, pp. 721-8, 2016.
A. Abhishek, Nakafero, G., Kuo, C. F., Mallen, C., Zhang, W., Grainge, M. J., and Doherty, M., Rheumatoid arthritis and excess mortality: down but not out. A primary care cohort study using data from Clinical Practice Research Datalink, Rheumatology (Oxford), vol. 57, pp. 977-981, 2018.
C. F. Kuo, Grainge, M. J., Mallen, C., Zhang, W., and Doherty, M., Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study, Ann Rheum Dis, vol. 74, pp. 661-7, 2015.
Z. Paskins, Whittle, R., Sultan, A. A., Muller, S., Blagojevic-Bucknall, M., Helliwell, T., Hider, S., Roddy, E., and Mallen, C., Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study, BMC Med, vol. 16, p. 4, 2018.
Z. Paskins, Whittle, R., A. Sultan, A., Muller, S., Blagojevic-Bucknall, M., Helliwell, T., Packham, J., Hider, S., Roddy, E., and Mallen, C., Risk of fragility fracture among patients with late-onset psoriasis: a UK population-based study, Osteoporos Int, vol. 29, pp. 1659-1664, 2018.
M. Blagojevic-Bucknall, Mallen, C., Muller, S., Hayward, R., West, S., Choi, H., and Roddy, E., The risk of gout among patients with sleep apnea: a matched cohort study, Arthritis Rheumatol, 2018.
S. Muller, Hider, S., Machin, A., Stack, R., Hayward, R. A., Raza, K., and Mallen, C., Searching for a prodrome for rheumatoid arthritis in the primary care record: A case-control study in the clinical practice research datalink, Semin Arthritis Rheum, 2018.
A. Sarmanova, Doherty, M., Kuo, C., Wei, J., Abhishek, A., Mallen, C., Zeng, C., Wang, Y., Lei, G., and Zhang, W., Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study, Rheumatology (Oxford), 2020.
S. Swain, Coupland, C., Mallen, C., Kuo, C. F., Sarmanova, A., Bierma-Zeinstra, S. M. A., Englund, M., Prieto-Alhambra, D., Doherty, M., and Zhang, W., Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting, Rheumatology (Oxford), 2021.
S. Swain, Sarmanova, A., Mallen, C., Kuo, C. F., Coupland, C., Doherty, M., and Zhang, W., Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD), Osteoarthritis Cartilage, 2020.
S. S. Zghebi, Rutter, M. K., Ashcroft, D. M., Salisbury, C., Mallen, C., Chew-Graham, C. A., Reeves, D., van Marwijk, H., Qureshi, N., Weng, S., Peek, N., Planner, C., Nowakowska, M., Mamas, M., and Kontopantelis, E., Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design, BMJ Open, vol. 8, p. e020926, 2018.
A. A. Sultan, Muller, S., Whittle, R., Roddy, E., Mallen, C., and Clarson, L., Venous thromboembolism in patients with gout and the impact of hospital admission, disease duration and urate-lowering therapy, Cmaj, vol. 191, pp. E597-e603, 2019.
G. Nakafero, Grainge, M. J., Valdes, A. M., Townsend, N., Mallen, C., Zhang, W., Doherty, M., Mamas, M., and Abhishek, A., β-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study, Rheumatology (Oxford), 2021.
[Page last reviewed 6 April 2021]