2018 |
Rheumatoid arthritis and excess mortality: down but not out. A primary care cohort study using data from Clinical Practice Research Datalink
10.1093/rheumatology/key013
Authors: A. Abhishek, G. Nakafero, C. Kuo, C. Mallen, W. Zhang, M. Grainge, M. Doherty |
2018 |
A retrospective observational analysis of post-pandemic influenza-related outcomes in the United Kingdom, 2010-2014
10.1080/21645515.2017.1403696
Authors: S. Rajaram, W. Wiecek, R. Lawson, B. Blak, Y. Zhao, J. Hackett, R. Brody, T. Salimi, B. Amzal, V. Patel |
2018 |
Representativeness of a digitally engaged population and a patient organisation population with rheumatoid arthritis and their willingness to participate in research: a cross-sectional study
10.1136/rmdopen-2018-000664
Authors: R. Costello, C. Jacklin, Jameson Evans, J. McBeth, W. Dixon |
2018 |
Reliability of coded data to identify earliest indications of cognitive decline, cognitive evaluation and Alzheimer\textquoterights disease diagnosis: a pilot study in England
10.1136/bmjopen-2017-019684
Authors: G. Dell\textquoterightAgnello, U. Desai, N . Y. Kirson, J. Wen, M. Meiselbach, C. Reed, M. Belger, A. Lenox-Smith, C. Martinez, J. Rasmussen |
2018 |
Relative toxicity of mood stabilisers and antipsychotics: case fatality and fatal toxicity associated with self-poisoning
10.1186/s12888-018-1993-3
Authors: A. Ferrey, G. Geulayov, D. Casey, C. Wells, A. Fuller, C. Bankhead, J. Ness, C. Clements, D. Gunnell, N. Kapur, K. Hawton |
2018 |
Relative toxicity of benzodiazepines and hypnotics commonly used for self-poisoning: An epidemiological study of fatal toxicity and case fatality
10.1177/0269881118754734
Authors: G. Geulayov, A. Ferrey, D. Casey, C. Wells, A. Fuller, C. Bankhead, D. Gunnell, C. Clements, N. Kapur, J. Ness, K. Waters, K. Hawton |
2018 |
Reintervention After Antireflux Surgery for Gastroesophageal Reflux Disease in England
10.1097/sla.0000000000003131
Authors: S. Markar, C. Arhi, T. Wiggins, A. Vidal-Diez, A. Karthikesalingam, A. Darzi, J. Lagergren, G. Hanna |
2018 |
Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research
10.1038/s41533-018-0089-3
Authors: J. Quint, E. Moore, A. Lewis, M. Hashmi, K. Sultana, M. Wright, L. Smeeth, L. Chatzidiakou, R. Jones, S. Beevers, S. Kolozali, F. Kelly, B. Barratt |
2018 |
Real-world presentation with heart failure in primary care: do patients selected to follow diagnostic and management guidelines have better outcomes?
10.1136/openhrt-2018-000935
Authors: A. Bottle, D. Kim, P. Aylin, F. Majeed, M. Cowie, B. Hayhoe |
2018 |
Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results
10.1136/bmjopen-2017-019475
Authors: K. Wing, E. Williamson, J. Carpenter, L. Wise, S. Schneeweiss, L. Smeeth, J. Quint, I. Douglas |
2018 |
Real-world effectiveness evaluation of budesonide/formoterol Spiromax for the management of asthma and chronic obstructive pulmonary disease in the UK
10.1136/bmjopen-2018-022051
Authors: J. Voorham, N. Roche, H. Benhaddi, M. van der Tol, V. Carter, J. van Boven, L. Bjermer, M. Miravitlles, D. Price |
2018 |
Quality of diabetes care in breast, colorectal, and prostate cancer
10.1007/s11764-018-0717-5
Authors: R. Griffiths, E. McFadden, R. Stevens, J. Valderas, B. Lavery, N. Khan, N. Keating, C. Bankhead |
2018 |
Psychiatric Comorbidities and Psychotropic Medication Use in Autism: A Matched Cohort Study with ADHD and General Population Comparator Groups in the United Kingdom
10.1002/aur.2040
Authors: R. Houghton, C. Liu, F. Bolognani |
2018 |
Pruritus is Common and Under-treated in Patients with Primary Biliary Cholangitis in the United Kingdom
10.1016/j.cgh.2018.12.007
Authors: V. Hegade, G. Mells, H. Fisher, S. Kendrick, J. DiBello, K. Gilchrist, G. Alexander, G. Hirschfield, R. Sandford, D. Jones |
2018 |
Proton Pump Inhibitor Use and Risk of Developing Alzheimer\textquoterights Disease or Vascular Dementia: A Case-Control Analysis
10.1007/s40264-018-0704-9
Authors: P. Imfeld, M. Bodmer, S. Jick, C. Meier |
2018 |
Prodromal symptoms of multiple sclerosis in primary care
10.1002/ana.25247
Authors: G. Disanto, C. Zecca, S. MacLachlan, R. Sacco, L. Handunnetthi, U. Meier, A. Simpson, L. McDonald, A. Rossi, P. Benkert, J. Kuhle, S. Ramagopalan, C. Gobbi |
2018 |
The prevalence, low-density lipoprotein cholesterol levels, and treatment of patients at very high risk of cardiovascular events in the United Kingdom: a cross-sectional study
10.1080/03007995.2018.1463211
Authors: M. Danese, E. Sidelnikov, L. Kutikova |
2018 |
Prescription patterns of angiotensin-converting enzyme inhibitors for various indications: A UK population-based study
10.1111/bcp.13692
Authors: S. Mahmoudpour, F. Asselbergs, P. Souverein, A. de Boer, A. van der Zee |
2018 |
Prescription of DPP-4 Inhibitors to Type 2 Diabetes Mellitus Patients With Renal Impairment: A UK Primary Care Experience
10.1016/j.clinthera.2017.11.009
Authors: D. Spanopoulos, B. Barrett, M. Busse, T. Roman, C. Poole |
2018 |
Prescription of DPP-4 Inhibitors to Patients With Adult Type 2 Diabetes Mellitus and Creatinine Clearance>50 mL/min: The UK Primary Care Experience
10.1016/j.clinthera.2018.06.002
Authors: D. Spanopoulos, B. Barrett, M. Busse, T. Roman, C. Poole |
2018 |
Prescribing of medication for attention deficit hyperactivity disorder among young people in the Clinical Practice Research Datalink 2005-2013: analysis of time to cessation
10.1007/s00787-017-1011-1
Authors: T. Newlove-Delgado, T. Ford, W. Hamilton, K. Stein, O. Ukoumunne |
2018 |
Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study
10.1093/rheumatology/key156
Authors: G. Nakafero, M. Grainge, P. Myles, C. Mallen, W. Zhang, M. Doherty, J. Nguyen-Van-Tam, A. Abhishek |
2018 |
Predicting the risk of emergency admission with machine learning: Development and validation using linked electronic health records
10.1371/journal.pmed.1002695
Authors: F. Rahimian, G. Salimi-Khorshidi, A. Payberah, J. Tran, Ayala Solares, F. Raimondi, M. Nazarzadeh, D. Canoy, K. Rahimi |
2018 |
Predicting surgical intervention in patients presenting with carpal tunnel syndrome in primary care
10.2147/clep.s154409
Authors: C. Burton, L. Chesterton, Y. Chen, D. van der Windt |
2018 |
Predicting prostate cancer progression: protocol for a retrospective cohort study to identify prognostic factors for prostate cancer outcomes using routine primary care data
10.1136/bmjopen-2017-019409
Authors: S. Merriel, M. May, R. Martin |
2018 |
Oral bisphosphonate use and age-related macular degeneration: retrospective cohort and nested case-control study
10.1111/nyas.13589
Authors: C. Garriga, M. Pazianas, S. Hawley, A. Delmestri, D. Prieto-Alhambra, C. Cooper, A. Judge |
2018 |
Low salivary cortisol levels in patients with rheumatoid arthritis exposed to oral glucocorticoids: a cross-sectional study set within UK electronic health records
10.1136/rmdopen-2018-000700
Authors: R. Joseph, D. Ray, B. Keevil, T. van Staa, W. Dixon |
2018 |
Psychiatric morbidity and suicidal behaviour in psoriasis: a primary care cohort study
10.1111/bjd.17004
Authors: R. Parisi, R. Webb, C. Kleyn, M. Carr, N. Kapur, C. Griffiths, D. Ashcroft |
2018 |
Low-Dose Aspirin Use Does Not Increase Survival in 2~Independent Population-Based Cohorts of Patients With~Esophageal or Gastric Cancer
10.1053/j.gastro.2017.10.044
Authors: A. Spence, J. Busby, B. Johnston, J. Baron, C. Hughes, H. Coleman, C. Cardwell |
2018 |
Maternal depression and antidepressant use during pregnancy and the risk of autism spectrum disorder in offspring
10.2147/clep.s180618
Authors: K. Hagberg, A. Robijn, S. Jick |
2018 |
Medication adherence among gout patients initiated allopurinol: a retrospective cohort study in the Clinical Practice Research Datalink (CPRD)
10.1093/rheumatology/key155
Authors: Lejm Scheepers, A. Burden, I. Arts, B. Spaetgens, P. Souverein, F. de Vries, A. Boonen |
2018 |
Methodological challenges when evaluating potential off-label prescribing of drugs using electronic health care databases: A case study of dabigatran etexilate in Europe
10.1002/pds.4416
Authors: M. Cainzos-Achirica, C. Varas-Lorenzo, A. Pottegard, J. Asmar, E. Plana, L. Rasmussen, G. Bizouard, J. Forns, M. Hellfritzsch, K. Zint, S. Perez-Gutthann, M. Pladevall-Vila |
2018 |
Mood Disorders and Risk of Herpes Zoster in 2 Population-Based Case-Control Studies in Denmark and the United Kingdom
10.1093/aje/kwx338
Authors: S. Schmidt, S. Langan, H. Pedersen, H. Schonheyder, S. Thomas, L. Smeeth, K. Mansfield, H. Sorensen, H. Forbes, M. Vestergaard |
2018 |
Mortality in Patients With Giant Cell Arteritis: A Cohort Study in UK Primary Care
10.1002/acr.23538
Authors: L. Li, T. Neogi, S. Jick |
2018 |
Mortality of the Severely Obese: A Population Study
10.1097/sla.0000000000002730
Authors: O. Moussa, S. Erridge, S. Chidambaram, P. Ziprin, A. Darzi, S. Purkayastha |
2018 |
Myocardial Infarction and Ischemic Stroke after Exacerbations of Chronic Obstructive Pulmonary Disease
10.1513/AnnalsATS.201710-815OC
Authors: K. Rothnie, O. Connell, H. Mullerova, L. Smeeth, N. Pearce, I. Douglas, J. Quint |
2018 |
Natural History of Chronic Obstructive Pulmonary Disease Exacerbations in a General Practice-based Population with Chronic Obstructive Pulmonary Disease
10.1164/rccm.201710-2029OC
Authors: K. Rothnie, H. Mullerova, L. Smeeth, J. Quint |
2018 |
Nontuberculous mycobacterial disease managed within UK primary care, 2006-2016
10.1007/s10096-018-3315-6
Authors: E. Axson, C. Bloom, J. Quint |
2018 |
Novel insights into the aetiology of granulomatosis with polyangiitis-a case-control study using the Clinical Practice Research Datalink
10.1093/rheumatology/kex512
Authors: F. Pearce, P. Lanyon, R. Watts, M. Grainge, A. Abhishek, R. Hubbard |
2018 |
Obesity and healthcare resource utilization: comparative results from the UK and the USA
10.1002/osp4.148
Authors: E. Nortoft, B. Chubb, A. Borglykke |
2018 |
Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
10.1002/osp4.291
Authors: C. le Roux, B. Chubb, E. Nortoft, A. Borglykke |
2018 |
An observational study of the use of acute hospital care by people with intellectual disabilities in England
10.1111/jir.12544
Authors: G. Glover, R. Williams, G. Tompkins, J. Oyinlola |
2018 |
Open-label, cluster randomised controlled trial and economic evaluation of a brief letter from a GP on unscheduled medical contacts associated with the start of the school year: the PLEASANT trial
10.1136/bmjopen-2017-017367
Authors: S. Julious, M. Horspool, S. Davis, M. Franklin, W. Smithson, P. Norman, R. Simpson, H. Elphick, O. Bortolami, C. Cooper |
2018 |
Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis suppurativa
10.1111/bjd.16101
Authors: J. Ingram, S. Jenkins-Jones, D. Knipe, C. Morgan, R. Cannings-John, V. Piguet |
2018 |
Poisoning substances taken by young people: a population-based cohort study
10.3399/bjgp18X698897
Authors: E. Tyrrell, D. Kendrick, K. Sayal, E. Orton |
2018 |
Polycystic ovary syndrome and autism: A test of the prenatal sex steroid theory
10.1038/s41398-018-0186-7
Authors: A. Cherskov, A. Pohl, C. Allison, H. Zhang, R. Payne, S. Baron-Cohen |
2018 |
Polycystic Ovary Syndrome Is Associated With Adverse Mental Health and Neurodevelopmental Outcomes
10.1210/jc.2017-02667
Authors: T. Berni, C. Morgan, E. Berni, D. Rees |
2018 |
Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia
10.1530/eje-17-0895
Authors: S. Jenkins-Jones, L. Parviainen, J. Porter, M. Withe, M. Whitaker, S. Holden, C. Morgan, C. Currie, R. Ross |
2018 |
The Potential of Glycemic Control and Body Weight Change as Early Markers for Pancreatic Cancer in Patients With Long-standing Diabetes Mellitus: A Case-Control Study
Authors: A. Mueller, C. Meier, S. Jick, C. Schneider |
2018 |
Practice variation in the use of tests in UK primary care: a retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16
10.1186/s12916-018-1217-1
Authors: J. O\textquoterightSullivan, S. Stevens, J. Oke, F. Hobbs, C. Salisbury, P. Little, B. Goldacre, C. Bankhead, J. Aronson, C. Heneghan, R. Perera |