Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,800 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 July 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 4MB, 236 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2833 results:
Author Title Type [ Year(Asc)]
L. J. Tata, West, J., Smith, C., Farrington, P., Card, T., Smeeth, L., and Hubbard, R., General population based study of the impact of tricyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction, Heart, vol. 91, pp. 465-71, 2005.
M. N. Cook, Girman, C. J., Stein, P. P., Alexander, C. M., and Holman, R. R., Glycemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes, Diabetes Care, vol. 28, pp. 995-1000, 2005.
T. R. Mikuls, Farrar, J. T., Bilker, W. B., Fernandes, S., Schumacher, Jr., H. R., and Saag, K. G., Gout epidemiology: results from the UK General Practice Research Database, 1990-1999, Ann Rheum Dis, vol. 64, pp. 267-72, 2005.
F. de Giuli, Khaw, K. T., Cowie, M. R., Sutton, G. C., Ferrari, R., and Poole-Wilson, P. A., Incidence and outcome of persons with a clinical diagnosis of heart failure in a general practice population of 696,884 in the United Kingdom, Eur J Heart Fail, vol. 7, pp. 295-302, 2005.
P. C. Souverein, Webb, D. J., Petri, H., Weil, J., van Staa, T. P., and Egberts, T., Incidence of fractures among epilepsy patients: a population-based retrospective cohort study in the General Practice Research Database, Epilepsia, vol. 46, pp. 304-10, 2005.
J. Logie, Clifford, G. M., and Farmer, R. D., Incidence, prevalence and management of lower urinary tract symptoms in men in the UK, BJU Int, vol. 95, pp. 557-62, 2005.
G. Gupta, Gelfand, J. M., and Lewis, J. D., Increased risk for demyelinating diseases in patients with inflammatory bowel disease, Gastroenterology, vol. 129, pp. 819-26, 2005.
M. C. Gulliford, Charlton, J., and Latinovic, R., Increased utilization of primary care 5 years before diagnosis of type 2 diabetes: a matched cohort study, Diabetes Care, vol. 28, pp. 47-52, 2005.
C. Joseph, Goddard, N., and Gelb, D., Influenza vaccine uptake and distribution in England and Wales using data from the General Practice Research Database, 1989/90-2003/04, J Public Health (Oxf), vol. 27, pp. 371-7, 2005.
V. A. Kiri, Bettoncelli, G., Testi, R., and Viegi, G., Inhaled corticosteroids are more effective in COPD patients when used with LABA than with SABA, Respir Med, vol. 99, pp. 1115-24, 2005.
V. A. Kiri, Pride, N. B., Soriano, J. B., and Vestbo, J., Inhaled corticosteroids in chronic obstructive pulmonary disease: results from two observational designs free of immortal time bias, Am J Respir Crit Care Med, vol. 172, pp. 460-4, 2005.
M. C. Gulliford, Adams, G., Ukoumunne, O. C., Latinovic, R., Chinn, S., and Campbell, M. J., Intraclass correlation coefficient and outcome prevalence are associated in clustered binary data, J Clin Epidemiol, vol. 58, pp. 246-51, 2005.
M. Solaymani-Dodaran, Logan, R. F., West, J., and Card, T., Mortality associated with Barrett's esophagus and gastroesophageal reflux disease diagnoses-a population-based cohort study, Am J Gastroenterol, vol. 100, pp. 2616-21, 2005.
R. Ryan, Newnham, A., Khunti, K., and Majeed, A., New cases of diabetes mellitus in England and Wales, 1994-1998: database study, Public Health, vol. 119, pp. 892-9, 2005.
G. M. Clifford, Logie, J., and Farmer, R. D., No risk of drug-associated liver injury with alpha1-adrenoreceptor blocking agents in men with BPH: results from an observational study using the GPRD, Pharmacoepidemiol Drug Saf, vol. 14, pp. 75-80, 2005.
C. Huerta, Castellsague, J., Varas-Lorenzo, C., and Rodriguez, L. A. Garcia, Nonsteroidal anti-inflammatory drugs and risk of ARF in the general population, Am J Kidney Dis, vol. 45, pp. 531-9, 2005.
B. D. Bradbury, Wilk, J. B., and Kaye, J. A., Obesity and the risk of prostate cancer (United States), Cancer Causes Control, vol. 16, pp. 637-41, 2005.
L. Watson, Kerstjens, H. A., Rabe, K. F., Kiri, V., Visick, G. T., and Postma, D. S., Obtaining optimal control in mild asthma: theory and practice, Fam Pract, vol. 22, pp. 305-10, 2005.
J. B. Soriano, Visick, G. T., Muellerova, H., Payvandi, N., and Hansell, A. L., Patterns of comorbidities in newly diagnosed COPD and asthma in primary care, Chest, vol. 128, pp. 2099-107, 2005.
A. Ruigomez, Johansson, S., Wallander, M. A., and Rodriguez, L. A. Garcia, Predictors and prognosis of paroxysmal atrial fibrillation in general practice in the UK, BMC Cardiovasc Disord, vol. 5, p. 20, 2005.
J. M. Gelfand, Weinstein, R., Porter, S. B., Neimann, A. L., Berlin, J. A., and Margolis, D. J., Prevalence and treatment of psoriasis in the United Kingdom: a population-based study, Arch Dermatol, vol. 141, pp. 1537-41, 2005.
D. Mines, Hill, D., Yu, H., and Novelli, L., Prevalence of risk factors for suicide in patients prescribed venlafaxine, fluoxetine, and citalopram, Pharmacoepidemiol Drug Saf, vol. 14, pp. 367-72, 2005.
A. G. Wade, Toumi, I., and Hemels, M. E., A probabilistic cost-effectiveness analysis of escitalopram, generic citalopram and venlafaxine as a first-line treatment of major depressive disorder in the UK, Curr Med Res Opin, vol. 21, pp. 631-42, 2005.
W. T. Hamilton, Gallagher, A. M., Thomas, J. M., and White, P. D., The prognosis of different fatigue diagnostic labels: a longitudinal survey, Fam Pract, vol. 22, pp. 383-8, 2005.
A. Gonzalez-Perez and Rodriguez, L. A. Garcia, Prostate cancer risk among men with diabetes mellitus (Spain), Cancer Causes Control, vol. 16, pp. 1055-8, 2005.
A. Alonso, Jick, S. S., Olek, M. J., Ascherio, A., Jick, H., and Hernan, M. A., Recent use of oral contraceptives and the risk of multiple sclerosis, Arch Neurol, vol. 62, pp. 1362-5, 2005.
J. D. Lewis, Bilker, W. B., Weinstein, R. B., and Strom, B. L., The relationship between time since registration and measured incidence rates in the General Practice Research Database, Pharmacoepidemiol Drug Saf, vol. 14, pp. 443-51, 2005.
C. Huerta, Lanes, S. F., and Rodriguez, L. A. Garcia, Respiratory medications and the risk of cardiac arrhythmias, Epidemiology, vol. 16, pp. 360-6, 2005.
S. Russmann, Kaye, J. A., Jick, S. S., and Jick, H., Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database, Br J Clin Pharmacol, vol. 60, pp. 76-82, 2005.
G. W. Hugenholtz, Heerdink, E. R., van Staa, T. P., Nolen, W. A., and Egberts, A. C., Risk of hip/femur fractures in patients using antipsychotics, Bone, vol. 37, pp. 864-70, 2005.
F. de Vries, van Staa, T. P., Bracke, M. S., Cooper, C., Leufkens, H. G., and Lammers, J. W., Severity of obstructive airway disease and risk of osteoporotic fracture, Eur Respir J, vol. 25, pp. 879-84, 2005.
T. P. van Staa, Geusens, P., Pols, H. A., de Laet, C., Leufkens, H. G., and Cooper, C., A simple score for estimating the long-term risk of fracture in patients using oral glucocorticoids, Qjm, vol. 98, pp. 191-8, 2005.
T. R. Mikuls, Farrar, J. T., Bilker, W. B., Fernandes, S., and Saag, K. G., Suboptimal physician adherence to quality indicators for the management of gout and asymptomatic hyperuricaemia: results from the UK General Practice Research Database (GPRD), Rheumatology (Oxford), vol. 44, pp. 1038-42, 2005.
M. Frisher, Crome, I., Macleod, J., Millson, D., and Croft, P., Substance misuse and psychiatric illness: prospective observational study using the general practice research database, J Epidemiol Community Health, vol. 59, pp. 847-50, 2005.
B. D. Bradbury, Lash, T. L., Kaye, J. A., and Jick, S. S., Tamoxifen-treated breast carcinoma patients and the risk of acute myocardial infarction and newly-diagnosed angina, Cancer, vol. 103, pp. 1114-21, 2005.
C. S. de Vries, Bromley, S. E., Thomas, H., and Farmer, R. D., Tibolone and endometrial cancer: a cohort and nested case-control study in the UK, Drug Saf, vol. 28, pp. 241-9, 2005.
L. Currin, Schmidt, U., Treasure, J., and Jick, H., Time trends in eating disorder incidence, Br J Psychiatry, vol. 186, pp. 132-5, 2005.
M. C. Gulliford, Charlton, J., and Latinovic, R., Trends in antihypertensive and lipid-lowering therapy in subjects with type II diabetes: clinical effectiveness or clinical discretion?, J Hum Hypertens, vol. 19, pp. 111-7, 2005.
Y. X. Yang, Hennessy, S., and Lewis, J. D., Type 2 diabetes mellitus and the risk of colorectal cancer, Clin Gastroenterol Hepatol, vol. 3, pp. 587-94, 2005.
L. A. Garcia Rodriguez and Gonzalez-Perez, A., Use of antibiotics and risk of breast cancer, Am J Epidemiol, vol. 161, pp. 616-9, 2005.
S. Dial, Delaney, J. A., Barkun, A. N., and Suissa, S., Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease, Jama, vol. 294, pp. 2989-95, 2005.
P. J. Helms, S. Daukes, E., Taylor, M. W., Simpson, C. R., and McLay, J. S., Utility of routinely acquired primary care data for paediatric disease epidemiology and pharmacoepidemiology, Br J Clin Pharmacol, vol. 59, pp. 684-90, 2005.
M. Ashworth, Charlton, J., Ballard, K., Latinovic, R., and Gulliford, M., Variations in antibiotic prescribing and consultation rates for acute respiratory infection in UK general practices 1995-2000, Br J Gen Pract, vol. 55, pp. 603-8, 2005.
P. Boyle, Roehrborn, C., Harkaway, R., Logie, J., de la Rosette, J., and Emberton, M., 5-Alpha reductase inhibition provides superior benefits to alpha blockade by preventing AUR and BPH-related surgery, Eur Urol, vol. 45, pp. 620-6; discussion 626-7, 2004.
T. P. van Staa, Travis, S., Leufkens, H. G., and Logan, R. F., 5-aminosalicylic acids and the risk of renal disease: a large British epidemiologic study, Gastroenterology, vol. 126, pp. 1733-9, 2004.
F. J. de Abajo, Montero, D., Madurga, M., and Rodriguez, L. A. Garcia, Acute and clinically relevant drug-induced liver injury: a population based case-control study, Br J Clin Pharmacol, vol. 58, pp. 71-80, 2004.
J. D. Lewis and Brensinger, C., Agreement between GPRD smoking data: a survey of general practitioners and a population-based survey, Pharmacoepidemiol Drug Saf, vol. 13, pp. 437-41, 2004.
T. Card, Logan, R. F., Rodrigues, L. C., and Wheeler, J. G., Antibiotic use and the development of Crohn's disease, Gut, vol. 53, pp. 246-50, 2004.
H. Jick, Kaye, J. A., and Jick, S. S., Antidepressants and the risk of suicidal behaviors, Jama, vol. 292, pp. 338-43, 2004.
S. V. Morant, Pettitt, D., MacDonald, T. M., Burke, T. A., and Goldstein, J. L., Application of a propensity score to adjust for channelling bias with NSAIDs, Pharmacoepidemiol Drug Saf, vol. 13, pp. 345-53, 2004.
[Page last reviewed 5 July 2021]