Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,800 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 July 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 4MB, 236 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2833 results:
Author Title Type [ Year(Asc)]
T. P. van Staa, Bishop, N., Leufkens, H. G., and Cooper, C., Are inhaled corticosteroids associated with an increased risk of fracture in children?, Osteoporos Int, vol. 15, pp. 785-91, 2004.
G. Ronquist, Rodriguez, L. A., Ruigomez, A., Johansson, S., Wallander, M. A., Frithz, G., and Svardsudd, K., Association between captopril, other antihypertensive drugs and risk of prostate cancer, Prostate, vol. 58, pp. 50-6, 2004.
H. Jick and Kaye, J. A., Autism and DPT vaccination in the United Kingdom, N Engl J Med, vol. 350, pp. 2722-3, 2004.
A. Gonzalez-Perez, Ronquist, G., and Rodriguez, L. A. Garcia, Breast cancer incidence and use of antihypertensive medication in women, Pharmacoepidemiol Drug Saf, vol. 13, pp. 581-5, 2004.
P. Mangtani, Cumberland, P., Hodgson, C. R., Roberts, J. A., Cutts, F. T., and Hall, A. J., A cohort study of the effectiveness of influenza vaccine in older people, performed using the United Kingdom general practice research database, J Infect Dis, vol. 190, pp. 1-10, 2004.
S. Hennessy, Bilker, W. B., Knauss, J. S., Kimmel, S. E., Margolis, D. J., Morrison, M. F., Reynolds, R. F., Glasser, D. B., and Strom, B. L., Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol, Br J Clin Pharmacol, vol. 58, pp. 81-7, 2004.
S. De Wilde, Carey, I. M., Bremner, S. A., Richards, N., Hilton, S. R., Strachan, D. P., and Cook, D. G., A comparison of the recording of 30 common childhood conditions in the Doctor's Independent Network and General Practice Research Databases, Health Stat Q, pp. 21-31, 2004.
R. G. Schlienger, Fischer, L. M., Jick, H., and Meier, C. R., Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction, Drug Saf, vol. 27, pp. 1157-65, 2004.
I. M. Carey, Cook, D. G., De Wilde, S., Bremner, S. A., Richards, N., Caine, S., Strachan, D. P., and Hilton, S. R., Developing a large electronic primary care database (Doctors' Independent Network) for research, Int J Med Inform, vol. 73, pp. 443-53, 2004.
L. M. Fischer, Schlienger, R. G., Matter, C. M., Jick, H., and Meier, C. R., Discontinuation of nonsteroidal anti-inflammatory drug therapy and risk of acute myocardial infarction, Arch Intern Med, vol. 164, pp. 2472-6, 2004.
M. L. Murray, de Vries, C. S., and Wong, I. C., A drug utilisation study of antidepressants in children and adolescents using the General Practice Research Database, Arch Dis Child, vol. 89, pp. 1098-102, 2004.
L. M. Fischer, Schlienger, R. G., Matter, C., Jick, H., and Meier, C. R., Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarction, Am J Cardiol, vol. 93, pp. 198-200, 2004.
C. Cooper, Dennison, E. M., Leufkens, H. G., Bishop, N., and van Staa, T. P., Epidemiology of childhood fractures in Britain: a study using the general practice research database, J Bone Miner Res, vol. 19, pp. 1976-81, 2004.
J. A. Kaye and Jick, H., Epidemiology of lower limb fractures in general practice in the United Kingdom, Inj Prev, vol. 10, pp. 368-74, 2004.
D. A. Van De Vijver, Walley, T., and Petri, H., Epidemiology of restless legs syndrome as diagnosed in UK primary care, Sleep Med, vol. 5, pp. 435-40, 2004.
A. Gaitatzis, Carroll, K., Majeed, A., and W. J, S., The epidemiology of the comorbidity of epilepsy in the general population, Epilepsia, vol. 45, pp. 1613-22, 2004.
T. Card, West, J., Hubbard, R., and Logan, R. F., Hip fractures in patients with inflammatory bowel disease and their relationship to corticosteroid use: a population based cohort study, Gut, vol. 53, pp. 251-5, 2004.
B. D. Bradbury and Jick, H., In vitro fertilization and childhood retinoblastoma, Br J Clin Pharmacol, vol. 58, pp. 209-11, 2004.
H. Jick, Kaye, J. A., and Black, C., Incidence and prevalence of drug-treated attention deficit disorder among boys in the UK, Br J Gen Pract, vol. 54, pp. 345-7, 2004.
A. M. Gallagher, Thomas, J. M., Hamilton, W. T., and White, P. D., Incidence of fatigue symptoms and diagnoses presenting in UK primary care from 1990 to 2001, J R Soc Med, vol. 97, pp. 571-5, 2004.
R. G. Schlienger, Jick, S. S., and Meier, C. R., Inhaled corticosteroids and the risk of fractures in children and adolescents, Pediatrics, vol. 114, pp. 469-73, 2004.
Y. X. Yang, Hennessy, S., and Lewis, J. D., Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients, Gastroenterology, vol. 127, pp. 1044-50, 2004.
L. A. Garcia Rodriguez and Gonzalez-Perez, A., Inverse association between nonsteroidal anti-inflammatory drugs and prostate cancer, Cancer Epidemiol Biomarkers Prev, vol. 13, pp. 649-53, 2004.
A. L. Nightingale and Farmer, R. D., Ischemic stroke in young women: a nested case-control study using the UK General Practice Research Database, Stroke, vol. 35, pp. 1574-8, 2004.
P. Cleary, Shorvon, S., and Tallis, R., Late-onset seizures as a predictor of subsequent stroke, Lancet, vol. 363, pp. 1184-6, 2004.
J. West, Logan, R. F., Smith, C. J., Hubbard, R. B., and Card, T. R., Malignancy and mortality in people with coeliac disease: population based cohort study, Bmj, vol. 329, pp. 716-9, 2004.
D. J. Margolis, Knauss, J., and Bilker, W., Medical conditions associated with venous leg ulcers, Br J Dermatol, vol. 150, pp. 267-73, 2004.
A. L. Hansell, Lam, K. A., Richardson, S., Visick, G., and Soriano, J. B., Medical event profiling of COPD patients, Pharmacoepidemiol Drug Saf, vol. 13, pp. 547-55, 2004.
L. Smeeth, Cook, C., Fombonne, E., Heavey, L., Rodrigues, L. C., Smith, P. G., and Hall, A. J., MMR vaccination and pervasive developmental disorders: a case-control study, Lancet, vol. 364, pp. 963-9, 2004.
A. Ruigomez, Rodriguez, L. A. Garcia, Wallander, M. A., Johansson, S., Graffner, H., and Dent, J., Natural history of gastro-oesophageal reflux disease diagnosed in general practice, Aliment Pharmacol Ther, vol. 20, pp. 751-60, 2004.
Z. Zhou, Althin, R., Sforzolini, B. S., and Dhawan, R., Persistency and treatment failure in newly diagnosed open angle glaucoma patients in the United Kingdom, Br J Ophthalmol, vol. 88, pp. 1391-4, 2004.
D. J. Torgerson, Sykes, D., Puffer, S., Brown, P., and Cooper, C., Pharmaceutical treatment of symptomatic vertebral fractures in primary care, Ann Rheum Dis, vol. 63, pp. 853-6, 2004.
M. M. Peng and Jick, H., A population-based study of the incidence, cause, and severity of anaphylaxis in the United Kingdom, Arch Intern Med, vol. 164, pp. 317-9, 2004.
M. Frisher, Collins, J., Millson, D., Crome, I., and Croft, P., Prevalence of comorbid psychiatric illness and substance misuse in primary care in England and Wales, J Epidemiol Community Health, vol. 58, pp. 1036-41, 2004.
M. A. Hernan, Logroscino, G., and Rodriguez, L. A., A prospective study of alcoholism and the risk of Parkinson's disease, J Neurol, vol. 251 Suppl 7, pp. vII14-7, 2004.
L. M. Howard, Goss, C., Leese, M., Appleby, L., and Thornicroft, G., The psychosocial outcome of pregnancy in women with psychotic disorders, Schizophr Res, vol. 71, pp. 49-60, 2004.
L. Smeeth, Cook, C., Fombonne, P. E., Heavey, L., Rodrigues, L. C., Smith, P. G., and Hall, A. J., Rate of first recorded diagnosis of autism and other pervasive developmental disorders in United Kingdom general practice, 1988 to 2001, BMC Med, vol. 2, p. 39, 2004.
M. A. Hernan, Jick, S. S., Olek, M. J., and Jick, H., Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study, Neurology, vol. 63, pp. 838-42, 2004.
S. J. Varney and Guest, J. F., Relative cost effectiveness of Depo-Provera, Implanon, and Mirena in reversible long-term hormonal contraception in the UK, Pharmacoeconomics, vol. 22, pp. 1141-51, 2004.
A. J. Apter, Kinman, J. L., Bilker, W. B., Herlim, M., Margolis, D. J., Lautenbach, E., Hennessy, S., and Strom, B. L., Represcription of penicillin after allergic-like events, J Allergy Clin Immunol, vol. 113, pp. 764-70, 2004.
J. M. Geoghegan, Clark, D. I., Bainbridge, L. C., Smith, C., and Hubbard, R., Risk factors in carpal tunnel syndrome, J Hand Surg Br, vol. 29, pp. 315-20, 2004.
L. A. Garcia Rodriguez and Gonzalez-Perez, A., Risk of breast cancer among users of aspirin and other anti-inflammatory drugs, Br J Cancer, vol. 91, pp. 525-9, 2004.
M. Solaymani-Dodaran, Logan, R. F., West, J., Card, T., and Coupland, C., Risk of extra-oesophageal malignancies and colorectal cancer in Barrett's oesophagus and gastro-oesophageal reflux, Scand J Gastroenterol, vol. 39, pp. 680-5, 2004.
L. Smeeth, Thomas, S. L., Hall, A. J., Hubbard, R., Farrington, P., and Vallance, P., Risk of myocardial infarction and stroke after acute infection or vaccination, N Engl J Med, vol. 351, pp. 2611-8, 2004.
C. R. Meier, Wilcock, K., and Jick, S. S., The risk of severe depression, psychosis or panic attacks with prophylactic antimalarials, Drug Saf, vol. 27, pp. 203-13, 2004.
J. West, Logan, R. F., Card, T. R., Smith, C., and Hubbard, R., Risk of vascular disease in adults with diagnosed coeliac disease: a population-based study, Aliment Pharmacol Ther, vol. 20, pp. 73-9, 2004.
J. D. Lewis, Aberra, F. N., Lichtenstein, G. R., Bilker, W. B., Brensinger, C., and Strom, B. L., Seasonal variation in flares of inflammatory bowel disease, Gastroenterology, vol. 126, pp. 665-73, 2004.
J. A. Kaye and Jick, H., Statin use and cancer risk in the General Practice Research Database, Br J Cancer, vol. 90, pp. 635-7, 2004.
S. S. Jick and Bradbury, B. D., Statins and newly diagnosed diabetes, Br J Clin Pharmacol, vol. 58, pp. 303-9, 2004.
J. R. Hardy, Holford, T. R., Hall, G. C., and Bracken, M. B., Strategies for identifying pregnancies in the automated medical records of the General Practice Research Database, Pharmacoepidemiol Drug Saf, vol. 13, pp. 749-59, 2004.
[Page last reviewed 5 July 2021]