Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 September 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


(PDF, 3MB, 189 pages)


Export 2324 results:
Author Title Type [ Year(Asc)]
S. Rajaram, Wiecek, W., Lawson, R., Blak, B. T., Zhao, Y., Hackett, J., Brody, R., Patel, V., and Amzal, B., Impact of increased influenza vaccination in 2-3-year-old children on disease burden within the general population: A Bayesian model-based approach, PLoS One, vol. 12, p. e0186739, 2017.
C. Allen and Donegan, K., The impact of regulatory action on the co-prescribing of renin-angiotensin system blockers in UK primary care, Pharmacoepidemiol Drug Saf, vol. 26, pp. 858-862, 2017.
S. L. Thomas, Walker, J. L., Fenty, J., Atkins, K. E., Elliot, A. J., Hughes, H. E., Stowe, J., Ladhani, S., and Andrews, N. J., Impact of the national rotavirus vaccination programme on acute gastroenteritis in England and associated costs averted, Vaccine, vol. 35, pp. 680-686, 2017.
A. Leite, Thomas, S. L., and Andrews, N. J., Implementing near real-time vaccine safety surveillance using the Clinical Practice Research Datalink (CPRD), Vaccine, vol. 35, pp. 6885-6892, 2017.
M. Gulliford, Ravindrarajah, R., Hamada, S., Jackson, S., and Charlton, J., Inception and deprescribing of statins in people aged over 80 years: cohort study, Age Ageing, vol. 46, pp. 1001-1005, 2017.
S. Weir, Samnaliev, M., Kuo, T. C., C. Choitir, N., Tierney, T. S., Cumming, D., Bruce, J., Manca, A., Taylor, R. S., and Eldabe, S., The incidence and healthcare costs of persistent postoperative pain following lumbar spine surgery in the UK: a cohort study using the Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES), BMJ Open, vol. 7, p. e017585, 2017.
V. W. Zhong, Juhaeri, J., Cole, S. R., Kontopantelis, E., Shay, C. M., Gordon-Larsen, P., and Mayer-Davis, E. J., Incidence and Trends in Hypoglycemia Hospitalization in Adults With Type 1 and Type 2 Diabetes in England, 1998-2013: A Retrospective Cohort Study, Diabetes Care, vol. 40, pp. 1651-1660, 2017.
C. Morgan, Webb, R. T., Carr, M. J., Kontopantelis, E., Green, J., Chew-Graham, C. A., Kapur, N., and Ashcroft, D. M., Incidence, clinical management, and mortality risk following self harm among children and adolescents: cohort study in primary care, Bmj, vol. 359, p. j4351, 2017.
L. Ban, Sprigg, N., A. Sultan, A., Nelson-Piercy, C., Bath, P. M., Ludvigsson, J. F., Stephansson, O., and Tata, L. J., Incidence of First Stroke in Pregnant and Nonpregnant Women of Childbearing Age: A Population-Based Cohort Study From England, J Am Heart Assoc, vol. 6, 2017.
H. Caspard, Wise, R. P., Steffey, A., and Brody, R. S., Incidence of live-attenuated influenza vaccine administration beyond expiry date in children and adolescents aged 2-17 years in the UK: a population-based cohort study, BMJ Open, vol. 7, p. e016520, 2017.
J. C. Wilson, Sarsour, K., Collinson, N., Tuckwell, K., Musselman, D., Klearman, M., Napalkov, P., Jick, S. S., Stone, J. H., and Meier, C. R., Incidence of outcomes potentially associated with corticosteroid therapy in patients with giant cell arteritis, Semin Arthritis Rheum, vol. 46, pp. 650-656, 2017.
F. A. Pearce, Grainge, M. J., Lanyon, P. C., Watts, R. A., and Hubbard, R. B., The incidence, prevalence and mortality of granulomatosis with polyangiitis in the UK Clinical Practice Research Datalink, Rheumatology (Oxford), vol. 56, pp. 589-596, 2017.
D. A. Springate, Parisi, R., Kontopantelis, E., Reeves, D., Griffiths, C. E., and Ashcroft, D. M., Incidence, prevalence and mortality of patients with psoriasis: a U.K. population-based cohort study, Br J Dermatol, vol. 176, pp. 650-658, 2017.
H. Liang, Manne, S., Shick, J., Lissoos, T., and Dolin, P., Incidence, prevalence, and natural history of primary sclerosing cholangitis in the United Kingdom, Medicine (Baltimore), vol. 96, p. e7116, 2017.
E. Roddy, Muller, S., Paskins, Z., Hider, S. L., Blagojevic-Bucknall, M., and Mallen, C. D., Incident acute pseudogout and prior bisphosphonate use: Matched case-control study in the UK-Clinical Practice Research Datalink, Medicine (Baltimore), vol. 96, p. e6177, 2017.
J. Granerod, Davies, N. W., Ramanuj, P. P., Easton, A., Brown, D. W., and Thomas, S. L., Increased rates of sequelae post-encephalitis in individuals attending primary care practices in the United Kingdom: a population-based retrospective cohort study, J Neurol, vol. 264, pp. 407-415, 2017.
B. Mars, Heron, J., Kessler, D., Davies, N. M., Martin, R. M., Thomas, K. H., and Gunnell, D., Influences on antidepressant prescribing trends in the UK: 1995-2011, Soc Psychiatry Psychiatr Epidemiol, vol. 52, pp. 193-200, 2017.
W. Tillett, Charlton, R., Nightingale, A., Snowball, J., Green, A., Smith, C., Shaddick, G., and McHugh, N., Interval between onset of psoriasis and psoriatic arthritis comparing the UK Clinical Practice Research Datalink with a hospital-based cohort, Rheumatology (Oxford), vol. 56, pp. 2109-2113, 2017.
F. A. Bietry, Hug, B., Reich, O., Susan, J. S., and Meier, C. R., Iron supplementation in Switzerland - A bi-national, descriptive and observational study, Swiss Med Wkly, vol. 147, p. w14444, 2017.
T. A. Yates, Tomlinson, L. A., Bhaskaran, K., Langan, S., Thomas, S., Smeeth, L., and Douglas, I. J., Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort, PLoS Med, vol. 14, p. e1002457, 2017.
A. K. Wright, Kontopantelis, E., Emsley, R., Buchan, I., Sattar, N., Rutter, M. K., and Ashcroft, D. M., Life Expectancy and Cause-Specific Mortality in Type 2 Diabetes: A Population-Based Cohort Study Quantifying Relationships in Ethnic Subgroups, Diabetes Care, vol. 40, pp. 338-345, 2017.
G. Bouras, Burns, E. M., Howell, A. M., Bottle, A., Athanasiou, T., and Darzi, A., Linked hospital and primary care database analysis of the impact of short-term complications on recurrence in laparoscopic inguinal hernia repair, Hernia, vol. 21, pp. 191-198, 2017.
S. Turner, Richardson, K., Murray, C., Thomas, M., Hillyer, E. V., Burden, A., and Price, D. B., Long-Acting beta-Agonist in Combination or Separate Inhaler as Step-Up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids, J Allergy Clin Immunol Pract, vol. 5, pp. 99-106.e3, 2017.
S. Suissa, Dell'Aniello, S., and Ernst, P., Long-Acting Bronchodilator Initiation in COPD and the Risk of Adverse Cardiopulmonary Events: A Population-Based Comparative Safety Study, Chest, vol. 151, pp. 60-67, 2017.
E. Kontopantelis, Parisi, R., Springate, D. A., and Reeves, D., Longitudinal multiple imputation approaches for body mass index or other variables with very low individual-level variability: the mibmi command in Stata, BMC Res Notes, vol. 10, p. 41, 2017.
J. H. Driessen, van den Bergh, J. P., van Onzenoort, H. A., Henry, R. M., Leufkens, H. G., and de Vries, F., Long-term use of dipeptidyl peptidase-4 inhibitors and risk of fracture: A retrospective population-based cohort study, Diabetes Obes Metab, vol. 19, pp. 421-428, 2017.
J. W. Wu, Azoulay, L., Majdan, A., Boivin, J. F., Pollak, M., and Suissa, S., Long-Term Use of Long-Acting Insulin Analogs and Breast Cancer Incidence in Women With Type 2 Diabetes, J Clin Oncol, vol. 35, pp. 3647-3653, 2017.
N. A. Francis, Entwistle, K., Santer, M., Layton, A. M., Eady, E. A., and Butler, C. C., The management of acne vulgaris in primary care: a cohort study of consulting and prescribing patterns using the Clinical Practice Research Datalink, Br J Dermatol, vol. 176, pp. 107-115, 2017.
M. D. Danese, Gleeson, M., Kutikova, L., Griffiths, R. I., Khunti, K., Seshasai, S. R. K., and Ray, K. K., Management of lipid-lowering therapy in patients with cardiovascular events in the UK: a retrospective cohort study, BMJ Open, vol. 7, p. e013851, 2017.
J. Gordon, McEwan, P., Evans, M., Puelles, J., and Sinclair, A., Managing glycaemia in older people with type 2 diabetes: A retrospective, primary care-based cohort study, with economic assessment of patient outcomes, Diabetes Obes Metab, vol. 19, pp. 644-653, 2017.
S. Lane, Lynn, E., and Shakir, S., Measuring the impact of product withdrawals and other major pharmacovigilance actions on public health burden in the EU: Methodological considerations, Drug Safety, vol. 40, pp. 953-4, 2017.
C. Seliger, Meier, C. R., Becker, C., Jick, S. S., Proescholdt, M., Bogdahn, U., Hau, P., and Leitzmann, M. F., Metabolic syndrome in relation to risk of meningioma, Oncotarget, vol. 8, pp. 2284-2292, 2017.
B. M. Hicks, Yin, H., Sinyavskaya, L., Suissa, S., Azoulay, L., and Brassard, P., Metformin and the incidence of viral associated cancers in patients with type 2 diabetes, Int J Cancer, vol. 141, pp. 121-128, 2017.
C. Becker, Jick, S. S., Meier, C. R., and Bodmer, M., Metformin and the risk of renal cell carcinoma: a case-control analysis, Eur J Cancer Prev, vol. 26, pp. 257-262, 2017.
M. D. Danese, Gleeson, M., Griffiths, R. I., Catterick, D., and Kutikova, L., Methods for estimating costs in patients with hyperlipidemia experiencing their first cardiovascular event in the United Kingdom, J Med Econ, vol. 20, pp. 931-937, 2017.
G. Glover, Williams, R., Heslop, P., Oyinlola, J., and Grey, J., Mortality in people with intellectual disabilities in England, J Intellect Disabil Res, vol. 61, pp. 62-74, 2017.
D. C. Perry, Metcalfe, D., Costa, M. L., and Van Staa, T., A nationwide cohort study of slipped capital femoral epiphysis, Arch Dis Child, vol. 102, pp. 1132-1136, 2017.
K. Bowman, Delgado, J., Henley, W. E., Masoli, J. A., Kos, K., Brayne, C., Thokala, P., Lafortune, L., Kuchel, G. A., Ble, A., and Melzer, D., Obesity in Older People With and Without Conditions Associated With Weight Loss: Follow-up of 955,000 Primary Care Patients, J Gerontol A Biol Sci Med Sci, vol. 72, pp. 203-209, 2017.
R. I. Griffiths, Valderas, J. M., McFadden, E. C., Bankhead, C. R., Lavery, B. A., Khan, N. F., Stevens, R. J., and Keating, N. L., Outcomes of preexisting diabetes mellitus in breast, colorectal, and prostate cancer, J Cancer Surviv, vol. 11, pp. 604-613, 2017.
J. Delgado, Masoli, J. A. H., Bowman, K., Strain, W. D., Kuchel, G. A., Walters, K., Lafortune, L., Brayne, C., Melzer, D., and Ble, A., Outcomes of Treated Hypertension at Age 80 and Older: Cohort Analysis of 79,376 Individuals, J Am Geriatr Soc, vol. 65, pp. 995-1003, 2017.
Z. Chaudhry, Mannan, F., Gibson-White, A., Syed, U., Ahmed, S., Kousoulis, A., and Majeed, A., Outputs and Growth of Primary Care Databases in the United Kingdom: Bibliometric Analysis, J Innov Health Inform, vol. 24, p. 942, 2017.
S. A. Schmidt, Vestergaard, M., Pedersen, H. S., Schonheyder, H. C., Thomas, S. L., Smeeth, L., Mansfield, K. E., Sorensen, H. T., Forbes, H. J., and Langan, S. M., Partner Bereavement and Risk of Herpes Zoster: Results from Two Population-Based Case-Control Studies in Denmark and the United Kingdom, Clin Infect Dis, vol. 64, pp. 572-579, 2017.
S. Stevens, Bankhead, C., Mukhtar, T., Perera-Salazar, R., Holt, T. A., Salisbury, C., and Hobbs, F. D. R., Patient-level and practice-level factors associated with consultation duration: a cross-sectional analysis of over one million consultations in English primary care, BMJ Open, vol. 7, p. e018261, 2017.
H. J. I. De Jong, van Staa, T. P., Lalmohamed, A., de Vries, F., Vandebriel, R. J., Van Loveren, H., Klungel, O. H., and Tervaert, J. W. Cohen, Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study, Ann Rheum Dis, vol. 76, pp. 1723-1730, 2017.
T. P. C. Chu, Moran, G. W., and Card, T. R., The Pattern of Underlying Cause of Death in Patients with Inflammatory Bowel Disease in England: A Record Linkage Study, J Crohns Colitis, vol. 11, pp. 578-585, 2017.
P. Datta-Nemdharry, Thomson, A., Beynon, J., and Donegan, K., Patterns of anti-diabetic medication use in patients with type 2 diabetes mellitus in England and Wales, Pharmacoepidemiol Drug Saf, vol. 26, pp. 127-135, 2017.
C. R. Chapple, Nazir, J., Hakimi, Z., Bowditch, S., Fatoye, F., Guelfucci, F., Khemiri, A., Siddiqui, E., and Wagg, A., Persistence and Adherence with Mirabegron versus Antimuscarinic Agents in Patients with Overactive Bladder: A Retrospective Observational Study in UK Clinical Practice, Eur Urol, vol. 72, pp. 389-399, 2017.
A. Douros, Yin, H., Yu, O. H. Y., Filion, K. B., Azoulay, L., and Suissa, S., Pharmacologic Differences of Sulfonylureas and the Risk of Adverse Cardiovascular and Hypoglycemic Events, Diabetes Care, vol. 40, pp. 1506-1513, 2017.
A. Farley, Koshiaris, C., Oke, J., Ryan, R., Szatkowski, L., Stevens, R., and Aveyard, P., Physician Support of Smoking Cessation After Diagnosis of Lung, Bladder, or Upper Aerodigestive Tract Cancer, Ann Fam Med, vol. 15, pp. 443-450, 2017.
R. Mathur, Bhaskaran, K., Edwards, E., Lee, H., Chaturvedi, N., Smeeth, L., and Douglas, I., Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014, BMJ Open, vol. 7, p. e014444, 2017.
[Page last reviewed 6 September 2019]