| 2022 |
Incidence of nonvalvular atrial fibrillation and oral anticoagulant prescribing in England, 2009 to 2019: A cohort study
10.1371/journal.pmed.1004003
Authors: A. Ajabnoor, S. Zghebi, R. Parisi, D. Ashcroft, M. Rutter, T. Doran, M. Carr, M. Mamas, E. Kontopantelis |
| 2022 |
Comparison of risk of serious cardiovascular events after haemorrhagic versus ischaemic stroke: a population-based study
10.1055/a-1873-9092
Authors: R. Akyea, G. Georgiopoulos, B. Iyen, J. Kai, N. Qureshi, G. Ntaios |
| 2022 |
Bilirubin levels and kidney function decline: An analysis of clinical trial and real world data
10.1371/journal.pone.0269970
Authors: Y. Aoki, C. Cabrera, M. Ouwens, K. Bamberg, J. Nyström, I. Raz, B. Scirica, B. Hamrén, P. Greasley, D. Rekić |
| 2022 |
Associations between frailty trajectories and cardiovascular, renal, and mortality outcomes in chronic kidney disease
10.1002/jcsm.13047
Authors: T. Wilkinson, J. Miksza, F. Zaccardi, C. Lawson, A. Nixon, H. Young, K. Khunti, A. Smith |
| 2022 |
Incremental value of risk factor variability for cardiovascular risk prediction in individuals with type 2 diabetes: results from UK primary care electronic health records
10.1093/ije/dyac140
Authors: Z. Xu, M. Arnold, L. Sun, D. Stevens, R. Chung, S. Ip, J. Barrett, S. Kaptoge, L. Pennells, E. Di Angelantonio, A. Wood |
| 2022 |
Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years
10.1136/bmjopen-2021-051456
Authors: S. Zghebi, D. Reeves, C. Grigoroglou, B. McMillan, D. Ashcroft, R. Parisi, E. Kontopantelis |
| 2022 |
Significant reduction in chronic kidney disease progression with sodium-glucose cotransporter-2 inhibitors compared to dipeptidyl peptidase-4 inhibitors in adults with type 2 diabetes in a UK clinical setting
10.1111/dom.14799
Authors: I. Idris, R. Zhang, J. Mamza, M. Ford, T. Morris, A. Banerjee, K. Khunti |
| 2022 |
The Association of Long-Acting Insulin Analogue Use Versus Neutral Protamine Hagedorn Insulin Use With Major Adverse Cardiovascular Events Among Individuals With Type 2 Diabetes: A Population-Based Cohort Study
10.1111/dom.14802
Authors: V. Brunetti, O. H. Y. Yu, R. Platt, K. Filion |
| 2022 |
Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.3 million individuals
10.1002/alz.12635
Authors: S. Chung, R. Providencia, R. Sofat, M. Pujades-Rodriguez, A. Torralbo, G. Fatemifar, N. Fitzpatrick, J. Taylor, K. Li, C. Dale, M. Rossor, D. Acosta-Mena, J. Whittaker, S. Denaxas |
| 2022 |
Linaclotide utilization and potential for off-label use and misuse in three European countries
10.1177/17562848221100946
Authors: J. Cid-Ruzafa, B. Lacy, A. Schultze, M. Duong, Y. Lu, M. Raluy-Callado, R. Donaldson, D. Weissman, A. Gómez-Lumbreras, D. Ouchi, M. Giner-Soriano, R. Morros, A. Ukah, D. Pohl |
| 2022 |
A retrospective cohort study measured predicting and validating the impact of the COVID-19 pandemic in individuals with chronic kidney disease
10.1016/j.kint.2022.05.015
Authors: A. Dashtban, M. Mizani, S. Denaxas, D. Nitsch, J. Quint, R. Corbett, J. Mamza, T. Morris, M. Mamas, D. Lawlor, K. Khunti, C. Sudlow, H. Hemingway, A. Banerjee |
| 2022 |
Primary Prevention of Cardiovascular and Heart Failure Events With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Their Combination in Type 2 Diabetes
10.2337/dc21-1113
Authors: A. Wright, M. Carr, E. Kontopantelis, L. Leelarathna, H. Thabit, R. Emsley, I. Buchan, M. Mamas, T. van Staa, N. Sattar, D. Ashcroft, M. Rutter |
| 2022 |
Associations of Cardiovascular and Non-Cardiovascular Comorbidities with Dementia Risk in Patients with Diabetes: Results from a Large UK Cohort Study
10.14283/jpad.2022.8
Authors: B. Zheng, B. Su, C. Udeh-Momoh, G. Price, I. Tzoulaki, E. Vamos, A. Majeed, E. Riboli, S. Ahmadi-Abhari, L. Middleton |
| 2021 |
Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study
10.1136/openhrt-2020-001498
Authors: S. Zghebi, M. Mamas, D. Ashcroft, M. Rutter, H. VanMarwijk, C. Salisbury, C. Mallen, C. Chew-Graham, N. Qureshi, S. Weng, T. Holt, I. Buchan, N. Peek, S. Giles, D. Reeves, E. Kontopantelis |
| 2021 |
Asthma phenotyping in primary care: applying the International Severe Asthma Registry eosinophil phenotype algorithm across all asthma severities
10.1016/j.jaip.2021.07.056
Authors: M. Kerkhof, T. Tran, R. Allehebi, G. Canonica, L. Heaney, M. Hew, Perez de Llano, M. Wechsler, L. Bulathsinhala, V. Carter, I. Chaudhry, N. Eleangovan, R. Murray, C. Price, D. Price |
| 2021 |
Atopic eczema in adulthood and mortality: UK population-based cohort study, 1998-2016
10.1016/j.jaci.2020.12.001
Authors: R. Silverwood, K. Mansfield, A. Mulick, A. Wong, S. Schmidt, A. Roberts, L. Smeeth, K. Abuabara, S. Langan |
| 2021 |
A Cohort Study to Evaluate the Risk of Hospitalisation for Congestive Heart Failure Associated with the Use of Aclidinium and Other Chronic Obstructive Pulmonary Disease Medications in the UK Clinical Practice Research Datalink
10.2147/copd.s301624
Authors: C. Rebordosa, E. Plana, A. Rubino, J. Aguado, A. Lei, S. Daoud, N. Saigi-Morgui, S. Perez-Gutthann, E. Rivero-Ferrer |
| 2021 |
Comparative Effectiveness of Initial LAMA versus LABA in COPD: Real-World Cohort Study
10.1080/15412555.2021.1877649
Authors: S. Suissa, S. Dell'Aniello, P. Ernst |
| 2021 |
Comparing initial LABA-ICS inhalers in COPD: Real-world effectiveness and safety
10.1016/j.rmed.2021.106645
Authors: S. Suissa, S. Dell'Aniello, P. Ernst |
| 2021 |
Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort
10.1001/jamanetworkopen.2021.5329
Authors: C. Dormuth, B. Winquist, A. Fisher, F. Wu, P. Reynier, S. Suissa, M. Dahl, Z. Ma, X. Lu, J. Zhang, C. Raymond, K. Filion, R. Platt, C. Moriello, J. Paterson |
| 2021 |
The Complex Association Between Bariatric Surgery and Depression: a National Nested-Control Study
10.1007/s11695-020-05201-z
Authors: C. Arhi, R. Dudley, O. Moussa, M. Ardissino, S. Scholtz, S. Purkayastha |
| 2021 |
The Impact of Demographic, Socio-Economic and Geographic Factors on Mortality Risk among People Living with Dementia in England (2002-2016)
10.3390/ijerph182413405
Authors: J. Watson, F. Darlington-Pollock, M. Green, C. Giebel, A. Akpan |
| 2021 |
Impact of influenza vaccination on amoxicillin prescriptions in older adults: A retrospective cohort study using primary care data
10.1371/journal.pone.0246156
Authors: L. Rodgers, A. Streeter, N. Lin, W. Hamilton, W. Henley |
| 2021 |
Incidence and survival of haemophagocytic lymphohistiocytosis: A population-based cohort study from England
10.1111/joim.13432
Authors: J. West, T. Card, M. Bishton, P. Lanyon, L. Ban, M. Bythell, L. Elliss-Brookes, J. Manson, V. Nanduri, J. Rankin, R. Tattersall, C. Crooks |
| 2021 |
Incidence, hospitalization and mortality and their changes over time in people with a first ever diabetic foot ulcer
10.1111/dme.14725
Authors: J. R\oikjer, N. Werkman, N. Ejskjaer, J. van den Bergh, P. Vestergaard, N. Schaper, M. Jensen, O. Klungel, F. de Vries, J. Nielen, J. Driessen, N. Ejskjaer, J. van den Bergh, P. Vestergaard, N. Schaper, Hasselstr\om Jensen, O. Klungel, F. de Vries, J. Nielen, J. Driessen, F. de Vries |
| 2021 |
Increased mortality risk in patients with primary and secondary adrenal insufficiency
10.1210/clinem/dgab096
Authors: K. Ngaosuwan, D. Johnston, I. Godsland, J. Cox, A. Majeed, J. Quint, N. Oliver, S. Robinson |
| 2021 |
The increasing incidence and prevalence of hypereosinophilic syndrome in the United Kingdom
10.1002/iid3.495
Authors: G. Requena, J. Logie, D. Gibbons, J. Steinfeld, M. Van Dyke |
| 2021 |
Incretin-Based Drugs and Risk of Intestinal Obstruction Among Patients with Type 2 Diabetes
10.1002/cpt.2430
Authors: J. Faillie, H. Yin, O. H. Y. Yu, A. Herrero, R. Altwegg, C. Renoux, L. Azoulay |
| 2021 |
Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study
10.1016/s2589-7500(21)00017-0
Authors: K. Mansfield, R. Mathur, J. Tazare, A. Henderson, A. Mulick, H. Carreira, A. Matthews, P. Bidulka, A. Gayle, H. Forbes, S. Cook, A. Wong, H. Strongman, K. Wing, C. Warren-Gash, S. Cadogan, L. Smeeth, J. Hayes, J. Quint, M. McKee, S. Langan |
| 2021 |
Inequalities in incident and prevalent multimorbidity in England, 2004\textendash19: a population-based, descriptive study
10.1016/S2666-7568(21)00146-X
Authors: A. Head, K. Fleming, C. Kypridemos, P. Schofield, J. Pearson-Stuttard, M. O\textquoterightFlaherty |
| 2021 |
Infection-related complications after common infection in association with new antibiotic prescribing in primary care: retrospective cohort study using linked electronic health records
10.1136/bmjopen-2020-041218
Authors: B. van Bodegraven, V. Palin, C. Mistry, M. Sperrin, A. White, W. Welfare, D. Ashcroft, T. van Staa |
| 2021 |
Trends in survival of older care home residents in England: A 10-year multi-cohort study
10.1016/j.socscimed.2021.113883
Authors: Espuny Pujol, R. Hancock, M. Morciano |
| 2021 |
Trends in the recording of anxiety in UK primary care: a multi-method approach
10.1007/s00127-021-02131-8
Authors: C. Archer, K. Turner, D. Kessler, B. Mars, N. Wiles |
| 2021 |
UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records
10.1186/s12889-021-10427-2
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| 2021 |
Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population-based assessment
10.1002/prp2.848
Authors: Y. Yu, K. Filion, P. Reynier, R. Platt, O. H. Y. Yu, S. Grandi |
| 2021 |
Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases
10.1136/bmj.n2182
Authors: Y. Vinogradova, T. Dening, J. Hippisley-Cox, L. Taylor, M. Moore, C. Coupland |
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The use of mono- and combination drug therapy in men and women with lower urinary tract symptoms (LUTS) in the UK: a retrospective observational study
10.1186/s12894-021-00881-w
Authors: M. Ali, M. Landeira, P. Covernton, N. Choudhury, A. Jaggi, F. Fatoye, R. van Maanen |
| 2021 |
Using electronic health records to inform trial feasibility in a rare autoimmune blistering skin disease in England
10.1186/s12874-021-01212-1
Authors: M. Persson, K. Harman, K. Thomas, J. Chalmers, Y. Vinogradova, S. Langan, J. Hippisley-Cox, S. Gran |
| 2021 |
Utilisation and Safety of Polyethylene Glycol 3350 with Electrolytes in Children Under 2 Years: A Retrospective Cohort
10.1097/mpg.0000000000003074
Authors: D. Roy, F. Akriche, B. Amlani, S. Shakir |
| 2021 |
Utilization and long-term persistence of direct oral anticoagulants among patients with non-valvular atrial fibrillation and liver disease
10.1111/bcp.15046
Authors: A. Douros, Y. Cui, R. Platt, K. Filion, G. Sebastiani, C. Renoux |
| 2021 |
The Utilization and Safety of Umeclidinium and Umeclidinium/Vilanterol in UK Primary Care: A Retrospective Cohort Study
10.2147/copd.s291931
Authors: G. Requena, D. Dedman, J. Quint, R. Ghosh, R. Williams, J. Pimenta |
| 2021 |
Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study
10.1186/s12913-021-06762-0
Authors: L. Lix, S. Sobhan, A. St-Jean, J. Daigle, A. Fisher, O. H. Y. Yu, S. Dell'Aniello, N. Hu, S. Bugden, B. Shah, P. Ronksley, S. Alessi-Severini, A. Douros, P. Ernst, K. Filion |
| 2021 |
Validity of bariatric surgery codes in the UK Clinical Practice Research Datalink (CPRD) GOLD compared with Hospital Episodes Statistics
10.1002/pds.5221
Authors: T. Burkard, M. Rauch, S. Jick, C. Meier |
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Vertebral fracture as a risk factor for self-harm: a retrospective cohort study
10.1186/s12891-021-04631-9
Authors: J. Prior, F. Crawford-Manning, R. Whittle, A. Abdul-Sultan, C. Chew-Graham, S. Muller, T. Shepherd, A. Sumathipala, C. Mallen, Z. Paskins |
| 2021 |
Weight change, cardio-metabolic risk factors and cardiovascular incidence in people with serious mental illness: protocol of a population-based cohort study in the UK from 1998 to 2020
10.1136/bmjopen-2021-053427
Authors: C. Lee, F. Waite, M. Smith, M. Gao, C. Bankhead, P. Aveyard, C. Piernas |
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wEight chanGes, caRdio-mEtabolic risks and morTality in patients with hyperthyroidism (EGRET): a protocol for a CPRD-HES linked cohort study
10.1136/bmjopen-2021-055219
Authors: B. Torlinska, J. Hazlehurst, K. Nirantharakumar, G. Thomas, J. Priestley, S. Finnikin, P. Saunders, K. Abrams, K. Boelaert |
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Weight loss and risk reduction of obesity-related outcomes in 0.5 million people: evidence from a UK primary care database
10.1038/s41366-021-00788-4
Authors: C. Haase, S. Lopes, A. Olsen, A. Satylganova, V. Schnecke, P. McEwan |
| 2021 |
What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?
10.1093/rheumatology/keab254
Authors: G. Nakafero, M. Grainge, T. Card, C. Mallen, W. Zhang, M. Doherty, M. Taal, G. Aithal, A. Abhishek |
| 2021 |
Women with Polycystic Ovary Syndrome have an increased risk of major cardiovascular events: a population study
10.1210/clinem/dgab392
Authors: T. Berni, C. Morgan, D. Rees |
| 2021 |
Younger people with rheumatoid arthritis are at increased risk of fracture even before age 50 years: a population-based cohort study
10.1007/s00198-021-05862-1
Authors: J. Erwin, D. Enki, A. Woolf |
