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Development of a treatment selection algorithm for SGLT2 and DPP-4 inhibitor therapies in people with type 2 diabetes: a retrospective cohort study
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Authors: J. Dennis, K. Young, A. McGovern, B. Mateen, S. Vollmer, M. Simpson, W. Henley, R. Holman, N. Sattar, E. Pearson, A. Hattersley, A. Jones, B. Shields |
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Inflammatory Diseases, Inflammatory Biomarkers, and Alzheimer Disease: An Observational Analysis and Mendelian Randomization
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Authors: J. Huang, B. Su, V. Karhunen, D. Gill, V. Zuber, A. Ahola-Olli, S. Palaniswamy, J. Auvinen, K. Herzig, S. Keinänen-Kiukaanniemi, M. Salmi, S. Jalkanen, T. Lehtimäki, V. Salomaa, O. Raitakari, P. Matthews, P. Elliott, K. Tsilidis, M. Jarvelin, I. Tzoulaki, A. Dehghan |
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Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study
10.1016/s2589-7500(22)00187-x
Authors: V. Kuan, S. Denaxas, P. Patalay, D. Nitsch, R. Mathur, A. Gonzalez-Izquierdo, R. Sofat, L. Partridge, A. Roberts, I. Wong, M. Hingorani, N. Chaturvedi, H. Hemingway, A. Hingorani |
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Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19-a data-driven retrospective cohort study
10.1177/01410768221131897
Authors: M. Mizani, A. Dashtban, L. Pasea, A. Lai, J. Thygesen, C. Tomlinson, A. Handy, J. Mamza, T. Morris, S. Khalid, F. Zaccardi, M. Macleod, F. Torabi, D. Canoy, A. Akbari, C. Berry, T. Bolton, J. Nolan, K. Khunti, S. Denaxas, H. Hemingway, C. Sudlow, A. Banerjee |
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Mental Health Morbidities and Time to Cancer Diagnosis Among Adults With Colon Cancer in England
10.1001/jamanetworkopen.2022.38569
Authors: Benitez Majano, G. Lyratzopoulos, N. de Wit, B. White, B. Rachet, C. Helsper, J. Usher-Smith, C. Renzi |
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TRial to Assess Implementation of New research in a primary care Setting (TRAINS): study protocol for a pragmatic cluster randomised controlled trial of an educational intervention to promote asthma prescription uptake in general practitioner practices
10.1186/s13063-022-06864-y
Authors: R. Alyami, R. Simpson, P. Oliver, S. Julious |
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Development and external validation of a risk prediction model for falls in patients with an indication for antihypertensive treatment: retrospective cohort study
10.1136/bmj-2022-070918
Authors: L. Archer, C. Koshiaris, S. Lay-Flurrie, K. Snell, R. Riley, R. Stevens, A. Banerjee, J. Usher-Smith, A. Clegg, R. Payne, F. Hobbs, R. McManus, J. Sheppard |
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Dihydropyridine Calcium Channel Blockers and Risk of Pancreatic Cancer: A Population-Based Cohort Study
10.1161/jaha.122.026789
Authors: J. Rouette, E. McDonald, T. Schuster, J. Brophy, L. Azoulay |
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Protocol for development and validation of postpartum cardiovascular disease (CVD) risk prediction model incorporating reproductive and pregnancy-related candidate predictors
10.1186/s41512-022-00137-7
Authors: S. Wambua, F. Crowe, S. Thangaratinam, D. O'Reilly, C. McCowan, S. Brophy, C. Yau, K. Nirantharakumar, R. Riley |
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Thrombosis and thrombocytopenia after vaccination against and infection with SARS-CoV-2 in the United Kingdom
10.1038/s41467-022-34668-w
Authors: E. Burn, X. Li, A. Delmestri, N. Jones, T. Duarte-Salles, C. Reyes, E. Martinez-Hernandez, E. Marti, K. Verhamme, P. Rijnbeek, V . Y. Strauss, D. Prieto-Alhambra |
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Incidence of anxiety and depression in children and young people with life-limiting conditions
10.1038/s41390-022-02370-8
Authors: M. Barker, B. Beresford, L. Fraser |
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Burden and treatment of chronic obstructive pulmonary disease among people using illicit opioids: matched cohort study in England
10.1136/bmjmed-2022-000215
Authors: D. Lewer, S. Cox, J. Hurst, P. Padmanathan, I. Petersen, J. Quint |
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Novel multimorbidity clusters in people with eczema and asthma: a population-based cluster analysis
10.1038/s41598-022-26357-x
Authors: A. Mulick, A. Henderson, D. Prieto-Merino, K. Mansfield, J. Matthewman, J. Quint, R. Lyons, A. Sheikh, D. McAllister, D. Nitsch, S. Langan |
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Examining methodology to identify patterns of consulting in primary care for different groups of patients before a diagnosis of cancer: An exemplar applied to oesophagogastric cancer
10.1016/j.canep.2022.102310
Authors: S. Price, B. Wiering, L. Mounce, W. Hamilton, G. Abel |
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Post-Authorization Safety Study of Hospitalization for Acute Kidney Injury in Patients with Type 2 Diabetes Exposed to Dapagliflozin in a Real-World Setting
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Authors: C. Johannes, D. Beachler, J. Layton, H. Danysh, R. Ziemiecki, A. Arana, J. Dinh, L. Li, B. Calingaert, M. Pladevall-Vila, P. Hunt, H. Chen, C. Karlsson, K. Johnsson, A. Gilsenan |
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Observational UK cohort study to describe intermittent oral corticosteroid prescribing patterns and their association with adverse outcomes in asthma
10.1136/thorax-2022-219642
Authors: H. Heatley, T. Tran, A. Bourdin, A. Menzies-Gow, D. Jackson, E. Maslova, J. Chapaneri, D. Skinner, V. Carter, J. Chan, C. Ariti, J. Haughney, D. Price |
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Association between polypharmacy and depression relapse in individuals with comorbid depression and type 2 diabetes: a UK electronic health record study
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Authors: A. Jeffery, C. Bhanu, K. Walters, I. Wong, D. Osborn, J. Hayes |
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Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records
10.1136/ebmental-2021-300355
Authors: R. Joseph, R. Jack, R. Morriss, R. Knaggs, D. Butler, C. Hollis, J. Hippisley-Cox, C. Coupland |
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Oral Anticoagulants and the Risk of Dementia in Patients With Nonvalvular Atrial Fibrillation: A Population-Based Cohort Study
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Authors: A. Rahman, J. Michaud, S. Dell'Aniello, E. Moodie, J. Brophy, M. Durand, J. Guertin, J. Boivin, C. Renoux |
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Risk prediction of mortality for patients with heart failure in England: observational study in primary care
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Authors: A. Bottle, R. Newson, P. Faitna, B. Hayhoe, M. Cowie |
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Machine Learning for Risk Prediction of Oesophago-Gastric Cancer in Primary Care: Comparison with Existing Risk-Assessment Tools
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Authors: E. Briggs, M. de Kamps, W. Hamilton, O. Johnson, C. McInerney, R. Neal |
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Obesity as a modifier of the cardiovascular effectiveness of sodium-glucose cotransporter-2 inhibitors in type 2 diabetes
10.1016/j.diabres.2022.110094
Authors: K. Suissa, S. Schneeweiss, A. Douros, H. Yin, E. Patorno, L. Azoulay |
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Recording of patients' mental health and quality of life-related outcomes in primary care: a cross-sectional study in the UK
10.1136/bmjopen-2022-066949
Authors: H. Carreira, R. Williams, H. Dempsey, K. Bhaskaran |
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Cardiovascular outcomes and mortality after incident ischaemic stroke in patients with a recent cancer history
10.1016/j.ejim.2022.12.006
Authors: R. Akyea, B. Iyen, G. Georgiopoulos, J. Kai, N. Qureshi, G. Ntaios |
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Methods to refine and extend a Pregnancy Register in the UK Clinical Practice Research Datalink primary care databases
10.1002/pds.5584
Authors: J. Campbell, H. Shepherd, S. Welburn, R. Barnett, J. Oyinlola, N. Oues, R. Williams |
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Post-Authorization Safety Studies of Acute Liver Injury and Severe Complications of Urinary Tract Infection in Patients with Type 2 Diabetes Exposed to Dapagliflozin in a Real-World Setting
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Authors: H. Danysh, C. Johannes, D. Beachler, J. Layton, R. Ziemiecki, A. Arana, J. Dinh, L. Li, B. Calingaert, M. Pladevall-Vila, P. Hunt, H. Chen, C. Karlsson, K. Johnsson, A. Gilsenan |
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Concomitant Use of Sulfonylureas and β-Blockers and the Risk of Severe Hypoglycemia Among Patients With Type 2 Diabetes: A Population-Based Cohort Study
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Authors: J. Dimakos, Y. Cui, R. Platt, C. Renoux, K. Filion, A. Douros |
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Common vaccines and the risk of incident dementia: a population-based cohort study
10.1093/infdis/jiac484
Authors: A. Douros, Z. Ante, S. Suissa, P. Brassard |
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Dupuytren's disease: Prevalence, incidence, and lifetime risk of surgical intervention A population-based cohort analysis
10.1097/prs.0000000000009919
Authors: D. Broekstra, R. Kuo, E. Burn, D. Prieto-Alhambra, D. Furniss |
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Patients with Chronic Obstructive Pulmonary Disease and Evidence of Eosinophilic Inflammation Experience Exacerbations Despite Receiving Maximal Inhaled Maintenance Therapy
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Authors: S. Chen, M. Miravitlles, C. Rhee, I. Pavord, R. Jones, V. Carter, B. Emmanuel, M. Alacqua, D. Price |
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Long-term oral antibiotic use in people with acne vulgaris in UK primary care: a drug utilization study
10.1093/bjd/ljac084
Authors: K. Bhate, K. Mansfield, S. Sinnott, D. Margolis, E. Adesanya, N. Francis, C. Leyrat, S. Hopkins, R. Stabler, L. Shallcross, S. Langan, R. Mathur |
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Association between mirtazapine use and serious self-harm in people with depression: an active comparator cohort study using UK electronic health records
10.1136/ebmental-2021-300355
Authors: R. Joseph, R. Jack, R. Morriss, R. Knaggs, D. Butler, C. Hollis, J. Hippisley-Cox, C. Coupland |
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Patterns of antiemetic medication use during pregnancy: A multi-country retrospective cohort study
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Primary care and cancer: an analysis of the impact and inequalities of the COVID-19 pandemic on patient pathways
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Frequency and Severity of Exacerbations of COPD Associated with Future Risk of Exacerbations and Mortality: A UK Routine Health Care Data Study
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Comparing antibiotic prescribing between clinicians in UK primary care: an analysis in a cohort study of eight different measures of antibiotic prescribing
10.1136/bmjqs-2020-012108
Authors: T. Van Staa, Y. Li, N. Gold, T. Chadborn, W. Welfare, V. Palin, D. Ashcroft, J. Bircher |
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UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): what does analysis of linked, routinely collected national data sets tell us about mid-late term revision risk after hip replacement? Retrospective cohort study
10.1136/bmjopen-2021-050877
Authors: L. Smith, C. Garriga, S. Kingsbury, R. Pinedo-Villanueva, A. Delmestri, N. Arden, M. Stone, P. Conaghan, A. Judge |
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Immortal time bias for life-long conditions in retrospective observational studies using electronic health records
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Authors: F. Tyrer, K. Bhaskaran, M. Rutherford |
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Screening for type 2 diabetes after a diagnosis of gestational diabetes by ethnicity: A retrospective cohort study
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Statin use is associated with lower risk of dementia in stroke patients: a community-based cohort study with inverse probability weighted marginal structural model analysis
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Authors: Z. Yang, S. Toh, X. Li, D. Edwards, C. Brayne, J. Mant |
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Intra-abdominal cancer risk with abdominal pain: a prospective cohort primary care study
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Authors: S. Price, N. Gibson, W. Hamilton, A. King, E. Shephard |
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Characteristics of New Users of Aclidinium Bromide, Aclidinium/Formoterol, and Other COPD Medications in the United Kingdom, Denmark, and Germany
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Authors: E. Rivero-Ferrer, M. Olesen, E. Plana, J. Aguado, N. Saigi-Morgui, A. Rubino, S. Daoud, A. Lei, S. Perez-Gutthann, T. Schink, N. Kristiansen, J. Hallas, A. Pottegard, C. Rebordosa |
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Effectiveness and safety of apixaban vs. rivaroxaban in patients with atrial fibrillation and type 2 diabetes mellitus
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Authors: Roy Chowdhury, J. Michaud, O. H. Y. Yu, H. Yin, L. Azoulay, C. Renoux |
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Long-Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study
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Antidepressant medication use in Inflammatory Bowel Disease: a nationally representative population-based study
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Authors: N. Jayasooriya, J. Blackwell, S. Saxena, A. Bottle, I. Petersen, H. Creese, M. Hotopf, R. Pollok |
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Characterization of the deterioration of diabetes control in patients with a subsequent diagnosis of pancreatic cancer: A descriptive study
10.1016/j.pan.2022.03.012
Authors: A. Mueller, C. Meier, S. Jick, C. Schneider |
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UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): what does analysis of linked, routinely collected national datasets tell us about mid-late term revision risk after knee replacement?
10.1136/bmjopen-2020-046900
Authors: L. Smith, C. Garriga, S. Kingsbury, R. Pinedo-Villanueva, A. Delmestri, N. Arden, M. Stone, P. Conaghan, A. Judge |
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Opioid use prior to total knee replacement: comparative analysis of trends in England and Sweden
10.1016/j.joca.2022.02.621
Authors: D. Yu, C. Hellberg, T. Appleyard, A. Dell'Isola, G. Thomas, A. Turkiewicz, M. Englund, G. Peat |
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Use of lifestyle interventions in primary care for individuals with newly diagnosed hypertension, hyperlipidaemia or obesity: a retrospective cohort study
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Authors: J. Lemp, M. Nuthanapati, T. Bärnighausen, S. Vollmer, P. Geldsetzer, A. Jani |
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Trends in the Annual Consultation Incidence and Prevalence of Low Back Pain and Osteoarthritis in England from 2000 to 2019: Comparative Estimates from Two Clinical Practice Databases
10.2147/clep.s337323
Authors: D. Yu, M. Missen, K. Jordan, J. Edwards, J. Bailey, R. Wilkie, J. Fitzpatrick, N. Ali, P. Niblett, G. Peat |
