Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,800 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 July 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 4MB, 236 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2833 results:
Author Title Type [ Year(Asc)]
L. A. Garcia Rodriguez and Hernandez-Diaz, S., The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents, Arthritis Res, vol. 3, pp. 98-101, 2001.
C. Vasilakis-Scaramozza and Jick, H., Risk of venous thromboembolism with cyproterone or levonorgestrel contraceptives, Lancet, vol. 358, pp. 1427-9, 2001.
T. M. McKeever, Lewis, S. A., Smith, C., Collins, J., Heatlie, H., Frischer, M., and Hubbard, R., Siblings, multiple births, and the incidence of allergic disease: a birth cohort study using the West Midlands general practice research database, Thorax, vol. 56, pp. 758-62, 2001.
S. Hernandez-Diaz and Rodriguez, L. A., Steroids and risk of upper gastrointestinal complications, Am J Epidemiol, vol. 153, pp. 1089-93, 2001.
C. Hodgson and Ellis, C., Time trends in GP outpatient referrals., Health Statistics Quartely, vol. 10, pp. 14-9, 2001.
M. Frischer, Heatlie, H., Norwood, J., Bashford, J., Millson, D., and Chapman, S., Trends in antibiotic prescribing and associated indications in primary care from 1993 to 1997, J Public Health Med, vol. 23, pp. 69-73, 2001.
A. Majeed, Moser, K., and Carroll, K., Trends in the prevalence and management of atrial fibrillation in general practice in England and Wales, 1994-1998: analysis of data from the general practice research database, Heart, vol. 86, pp. 284-8, 2001.
T. P. van Staa, Leufkens, H. G., and Cooper, C., Use of inhaled corticosteroids and risk of fractures, J Bone Miner Res, vol. 16, pp. 581-8, 2001.
C. R. Meier, Schlienger, R. G., and Jick, H., Use of selective serotonin reuptake inhibitors and risk of developing first-time acute myocardial infarction, Br J Clin Pharmacol, vol. 52, pp. 179-84, 2001.
T. P. van Staa, Wegman, S., de Vries, F., Leufkens, B., and Cooper, C., Use of statins and risk of fractures, Jama, vol. 285, pp. 1850-5, 2001.
S. Rowlands, Devalia, H., and Lawrenson, R., Use of the combined oral contraceptive pill by under 16s, J Fam Plann Reprod Health Care, vol. 27, pp. 17-9, 2001.
R. Hubbard and Venn, A., Adult height and cryptogenic fibrosing alveolitis: a case-control study using the UK general practice research database, Thorax, vol. 55, pp. 864-6, 2000.
A. Majeed, Moser, K., and Maxwell, R., Age, sex and practice variations in the use of statins in general practice in England and Wales, J Public Health Med, vol. 22, pp. 275-9, 2000.
C. R. Meier, Derby, L. E., Jick, S. S., and Jick, H., Angiotensin-converting enzyme inhibitors, calcium channel blockers, and breast cancer, Arch Intern Med, vol. 160, pp. 349-53, 2000.
C. R. Meier, Antibiotics in the prevention and treatment of coronary heart disease, J Infect Dis, vol. 181 Suppl 3, pp. S558-62, 2000.
M. W. Myers, Vasilakis, C., Kaufman, M. R., and Jick, H., Antihypertensive drugs and the risk of idiopathic aplastic anaemia, Br J Clin Pharmacol, vol. 49, pp. 604-8, 2000.
G. L. Zornberg and Jick, H., Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study, Lancet, vol. 356, pp. 1219-23, 2000.
A. Ruigomez, Rodriguez, L. A. Garcia, Dev, V. J., Arellano, F., and Raniwala, J., Are schizophrenia or antipsychotic drugs a risk factor for cataracts?, Epidemiology, vol. 11, pp. 620-3, 2000.
D. Millson, Frischer, M., Croft, P., and Goadsby, P. J., Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?, Cephalalgia, vol. 20, pp. 732-7, 2000.
S. F. Lanes, Rodrigeuz, L. A., and Hwangg, E., Baseline risk of gastrointestinal disorders among new users of meloxicam, ibuprofen, diclofenac, naproxen and indomethacin, Pharmacoepidemiol Drug Saf, vol. 9, pp. 113-7, 2000.
R. D. Farmer, Lawrenson, R. A., Todd, J. C., Williams, T. J., MacRae, K. D., Tyrer, F., and Leydon, G. M., A comparison of the risks of venous thromboembolic disease in association with different combined oral contraceptives, Br J Clin Pharmacol, vol. 49, pp. 580-90, 2000.
M. Frischer, Norwood, J., Heatlie, H., Millson, D., Lowdell, J., Hickman, M., Chapman, S., and Bashford, J., A comparison of trends in problematic drug misuse from two reporting systems, J Public Health Med, vol. 22, pp. 362-7, 2000.
M. Frischer, Heatlie, H., Chapman, S., and Millson, D., Defining the spectrum of appropriate prescribing: implications for effective medicines management, International Journal of Pharmaceutical Medicine, vol. 14, pp. 17-21, 2000.
L. A. Garcia Rodriguez, Ruigomez, A., Wallander, M. A., Johansson, S., and Olbe, L., Detection of colorectal tumor and inflammatory bowel disease during follow-up of patients with initial diagnosis of irritable bowel syndrome, Scand J Gastroenterol, vol. 35, pp. 306-11, 2000.
L. A. Garcia Rodriguez, Varas, C., and Patrono, C., Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women, Epidemiology, vol. 11, pp. 382-7, 2000.
R. D. Farmer, Williams, T. J., Simpson, E. L., and Nightingale, A. L., Effect of 1995 pill scare on rates of venous thromboembolism among women taking combined oral contraceptives: analysis of general practice research database, Bmj, vol. 321, pp. 477-9, 2000.
M. J. Langman, Cheng, K. K., Gilman, E. A., and Lancashire, R. J., Effect of anti-inflammatory drugs on overall risk of common cancer: case-control study in general practice research database, Bmj, vol. 320, pp. 1642-6, 2000.
A. L. Nightingale, Lawrenson, R. A., Simpson, E. L., Williams, T. J., MacRae, K. D., and Farmer, R. D., The effects of age, body mass index, smoking and general health on the risk of venous thromboembolism in users of combined oral contraceptives, Eur J Contracept Reprod Health Care, vol. 5, pp. 265-74, 2000.
D. Gupta, Hansell, A., Nichols, T., Duong, T., Ayres, J. G., and Strachan, D., Epidemiology of pneumothorax in England, Thorax, vol. 55, pp. 666-71, 2000.
R. Hubbard, Venn, A., and Britton, J., Exposure to antidepressants and the risk of cryptogenic fibrosing alveolitis: a case-control study, Eur Respir J, vol. 16, pp. 409-13, 2000.
C. R. Meier, Schlienger, R. G., Kraenzlin, M. E., Schlegel, B., and Jick, H., HMG-CoA reductase inhibitors and the risk of fractures, Jama, vol. 283, pp. 3205-10, 2000.
C. Varas-Lorenzo, Garcia-Rodriguez, L. A., Perez-Gutthann, S., and Duque-Oliart, A., Hormone replacement therapy and incidence of acute myocardial infarction. A population-based nested case-control study, Circulation, vol. 101, pp. 2572-8, 2000.
G. M. Clifford, Logie, J., and Farmer, R. D., How do symptoms indicative of BPH progress in real life practice? The UK experience, Eur Urol, vol. 38 Suppl 1, pp. 48-53, 2000.
delMar M. Melero-Montes and Jick, H., Hyperemesis Gravidarum and the Sex of the Offspring, Epidemiology, vol. 12, pp. 123-124, 2000.
J. A. Kaye, Derby, L. E., M. Melero-Montes, delMar, Quinn, M., and Jick, H., The incidence of breast cancer in the General Practice Research Database compared with national cancer registration data, Br J Cancer, vol. 83, pp. 1556-8, 2000.
C. Gasse, Derby, L., Vasilakis-Scaramozza, C., and Jick, H., Incidence of first-time idiopathic seizures in users of tramadol, Pharmacotherapy, vol. 20, pp. 629-34, 2000.
H. Jick, Incidence of venous thromboembolism in users of combined oral contraceptives. Methods for identifying cases and estimating person time at risk must be detailed, Bmj, vol. 320, pp. 57; author reply 57-8, 2000.
F. J. de Abajo, Jick, H., Derby, L., Jick, S., and Schmitz, S., Intracranial haemorrhage and use of selective serotonin reuptake inhibitors, Br J Clin Pharmacol, vol. 50, pp. 43-7, 2000.
S. S. Jick, Kremers, H. M., and Vasilakis-Scaramozza, C., Isotretinoin use and risk of depression, psychotic symptoms, suicide, and attempted suicide, Arch Dermatol, vol. 136, pp. 1231-6, 2000.
R. Hubbard, Venn, A., Lewis, S., and Britton, J., Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study, Am J Respir Crit Care Med, vol. 161, pp. 5-8, 2000.
P. J. Tooley, Cookson, R. F., Jones, M., and Nuyts, G. D., Medical events and resource utilisation in cancer-pain patients treated with strong opioids: an analysis of the UK General Practice Research Database, Journal of Drug Assessment, vol. 3, pp. 221-233, 2000.
R. A. Marrie, Wolfson, C., Sturkenboom, M. C., Gout, O., Heinzlef, O., Roullet, E., and Abenhaim, L., Multiple sclerosis and antecedent infections: a case-control study, Neurology, vol. 54, pp. 2307-10, 2000.
T. P. van Staa, Leufkens, H. G., Abenhaim, L., Zhang, B., and Cooper, C., Oral corticosteroids and fracture risk: relationship to daily and cumulative doses, Rheumatology (Oxford), vol. 39, pp. 1383-9, 2000.
A. Ruigomez, Rodriguez, L. A. Garcia, Hasselgren, G., Johansson, S., and Wallander, M. A., Overall mortality among patients surviving an episode of peptic ulcer bleeding, J Epidemiol Community Health, vol. 54, pp. 130-3, 2000.
B. Ineichen, Logie, J., Rowlands, S., and Lawrenson, R., Patterns of prescription of PC4 by general practitioners in England and Wales, Eur J Contracept Reprod Health Care, vol. 5, pp. 241-7, 2000.
C. R. Meier, Napalkov, P. N., Wegmuller, Y., Jefferson, T., and Jick, H., Population-based study on incidence, risk factors, clinical complications and drug utilisation associated with influenza in the United Kingdom, Eur J Clin Microbiol Infect Dis, vol. 19, pp. 834-42, 2000.
M. Frischer, Heatlie, H., Chapman, S., Bashford, J., Norwood, J., and Millson, D., Ratio of inhaled corticosteroid to bronchodilator treatment and asthma hospitalisation, Curr Med Res Opin, vol. 16, pp. 8-13, 2000.
J. B. Soriano, Maier, W. C., Egger, P., Visick, G., Thakrar, B., Sykes, J., and Pride, N. B., Recent trends in physician diagnosed COPD in women and men in the UK, Thorax, vol. 55, pp. 789-94, 2000.
L. A. Garcia Rodriguez and Huerta-Alvarez, C., Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: a pooled analysis of published studies and a new population-based study, Epidemiology, vol. 11, pp. 376-81, 2000.
S. Rowlands, Devalia, H., Lawrenson, R., Logie, J., and Ineichen, B., Repeated use of hormonal emergency contraception by younger women in the UK, Br J Fam Plann, vol. 26, pp. 138-43, 2000.
[Page last reviewed 5 July 2021]