Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,800 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 July 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 4MB, 236 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2833 results:
Author Title Type [ Year(Asc)]
H. Jick, Vasilakis, C., Weinrauch, L. A., Meier, C. R., Jick, S. S., and Derby, L. E., A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation, N Engl J Med, vol. 339, pp. 719-24, 1998.
T. P. van Staa, Leufkens, H., Abenhaim, L., and Cooper, C., Postmarketing surveillance of the safety of cyclic etidronate, Pharmacotherapy, vol. 18, pp. 1121-8, 1998.
C. R. Meier, Sturkenboom, M. C., Cohen, A. S., and Jick, H., Postmenopausal estrogen replacement therapy and the risk of developing systemic lupus erythematosus or discoid lupus, J Rheumatol, vol. 25, pp. 1515-9, 1998.
F. Haste, Charlton, J., and Jenkins, R., Potential for suicide prevention in primary care? An analysis of factors associated with suicide, Br J Gen Pract, vol. 48, pp. 1759-63, 1998.
S. S. Jick, Vasilakis, C., and Jick, H., Pregnancies and terminations after 1995 warning about third-generation oral contraceptives, Lancet, vol. 351, pp. 1404-5, 1998.
D. J. Torgerson and Dolan, P., Prescribing by general practitioners after an osteoporotic fracture, Ann Rheum Dis, vol. 57, pp. 378-9, 1998.
A. Ruigomez and Rodriguez, L. A. Garcia, Presence of diabetes related complication at the time of NIDDM diagnosis: an important prognostic factor, Eur J Epidemiol, vol. 14, pp. 439-45, 1998.
S. de Lusignan, Brown, A., and Majeed, A., Recent developments in general practice computing, Clinician in Management, vol. 7, pp. 148-154, 1998.
J. Castellsague, S. Gutthann, P., and Rodriguez, L. A. Garcia, Recent epidemiological studies of the association between hormone replacement therapy and venous thromboembolism. A review, Drug Saf, vol. 18, pp. 117-23, 1998.
R. G. Gibbs, Todd, J. C., Irvine, C., Lawrenson, R., Newson, R., Greenhalgh, R. M., and Davies, A. H., Relationship between the regional and national incidence of transient ischaemic attack and stroke and performance of carotid endarterectomy, Eur J Vasc Endovasc Surg, vol. 16, pp. 47-52, 1998.
L. A. Garcia Rodriguez, Cattaruzzi, C., Troncon, M. G., and Agostinis, L., Risk of hospitalization for upper gastrointestinal tract bleeding associated with ketorolac, other nonsteroidal anti-inflammatory drugs, calcium antagonists, and other antihypertensive drugs, Arch Intern Med, vol. 158, pp. 33-9, 1998.
H. Jick, Derby, L. E., Vasilakis, C., and Fife, D., The risk of seizures associated with tramadol, Pharmacotherapy, vol. 18, pp. 607-11, 1998.
T. Lancaster, Swart, A. M., and Jick, H., Risk of serious haematological toxicity with use of chloramphenicol eye drops in a British general practice database, Bmj, vol. 316, p. 667, 1998.
S. S. Jick, Vasilakis, C., Martinez, C., and Jick, H., A study of the relation of exposure to quinolones and suicidal behaviour, Br J Clin Pharmacol, vol. 45, pp. 77-81, 1998.
C. R. Meier and Jick, H., Tamoxifen and risk of idiopathic venous thromboembolism, Br J Clin Pharmacol, vol. 45, pp. 608-12, 1998.
M. W. Myers and Jick, H., Terfenadine and risk of acute liver disease, Br J Clin Pharmacol, vol. 46, pp. 251-3, 1998.
T. P. van Staa, Abenhaim, L., and Cooper, C., Use of cyclical etidronate and prevention of non-vertebral fractures, Br J Rheumatol, vol. 37, pp. 87-94, 1998.
L. A. Garcia Rodriguez and S. Gutthann, P., Use of the UK General Practice Research Database for pharmacoepidemiology, Br J Clin Pharmacol, vol. 45, pp. 419-25, 1998.
J. N. Bashford, Norwood, J., and Chapman, S. R., Why are patients prescribed proton pump inhibitors? Retrospective analysis of link between morbidity and prescribing in the General Practice Research Database, Bmj, vol. 317, pp. 452-6, 1998.
A. M. Walker, Szneke, P., Bianchi, L. A., Field, L. G., Sutherland, L. R., and Dreyer, N. A., 5-Aminosalicylates, sulfasalazine, steroid use, and complications in patients with ulcerative colitis, Am J Gastroenterol, vol. 92, pp. 816-20, 1997.
S. S. Jick and Terris, B. Z., Anticonvulsants and congenital malformations, Pharmacotherapy, vol. 17, pp. 561-4, 1997.
H. Jick, Vasilakis, C., and Derby, L. E., Antihypertensive drugs and fatal myocardial infarction in persons with uncomplicated hypertension, Epidemiology, vol. 8, pp. 446-8, 1997.
H. Jick, Calcium-channel blockers and risk of cancer, Lancet, vol. 349, pp. 1699-700, 1997.
S. Jick, Ciprofloxacin safety in a pediatric population, Pediatr Infect Dis J, vol. 16, pp. 130-3; discussion 133-4, 160-2, 1997.
C. R. Meier and Jick, H., Drug use and pulmonary death rates in increasingly symptomatic asthma patients in the UK, Thorax, vol. 52, pp. 612-7, 1997.
L. A. Garcia Rodriguez and Ruigomez, A., Gastric acid, acid-suppressing drugs, and bacterial gastroenteritis: how much of a risk?, Epidemiology, vol. 8, pp. 571-4, 1997.
J. Hollowell, The General Practice Research Database: quality of morbidity data, Popul Trends, pp. 36-40, 1997.
P. S. Gutthann, Rodriguez, L. A. Garcia, Castellsague, J., and A. Oliart, D., Hormone replacement therapy and risk of venous thromboembolism: population based case-control study, Bmj, vol. 314, pp. 796-800, 1997.
C. R. Meier and Jick, H., Omeprazole, H2 blockers, and polyarthralgia: case-control study, Bmj, vol. 315, p. 1283, 1997.
C. R. Meier and Jick, H., Omeprazole, other antiulcer drugs and newly diagnosed gout, Br J Clin Pharmacol, vol. 44, pp. 175-8, 1997.
T. Van Staa, Abenhaim, L., and Monette, J., Rates of hypoglycemia in users of sulfonylureas, J Clin Epidemiol, vol. 50, pp. 735-41, 1997.
L. A. Garcia Rodriguez, Wallander, M. A., Johanson, S., and Bjorck, S., Renal disease and acid-suppressing drugs, Pharmacoepidemiol Drug Saf, vol. 6, pp. 247-51, 1997.
L. A. Garcia Rodriguez, Ruigomez, A., and Jick, H., A review of epidemiologic research on drug-induced acute liver injury using the general practice research data base in the United Kingdom, Pharmacotherapy, vol. 17, pp. 721-8, 1997.
L. A. Garcia Rodriguez, Wallander, M. A., and Stricker, B. H., The risk of acute liver injury associated with cimetidine and other acid-suppressing anti-ulcer drugs, Br J Clin Pharmacol, vol. 43, pp. 183-8, 1997.
S. Hajat, Goubet, S. A., and Haines, A., Thunderstorm-associated asthma: the effect on GP consultations, Br J Gen Pract, vol. 47, pp. 639-41, 1997.
T. Van Staa, Abenhaim, L., and Cooper, C., Upper gastrointestinal adverse events and cyclical etidronate, Am J Med, vol. 103, pp. 462-7, 1997.
L. A. Garcia Rodriguez, Mannino, S., Wallander, M. A., and Lindblom, B., A cohort study of the ocular safety of anti-ulcer drugs, Br J Clin Pharmacol, vol. 42, pp. 213-6, 1996.
S. Turnbull, Ward, A., Treasure, J., Jick, H., and Derby, L., The demand for eating disorder care. An epidemiological study using the general practice research database, Br J Psychiatry, vol. 169, pp. 705-12, 1996.
L. A. Garcia Rodriguez, Stricker, B. H., and Zimmerman, H. J., Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid, Arch Intern Med, vol. 156, pp. 1327-32, 1996.
H. Jick, Derby, L. E., Gurewich, V., and Vasilakis, C., The risk of myocardial infarction associated with antihypertensive drug treatment in persons with uncomplicated essential hypertension, Pharmacotherapy, vol. 16, pp. 321-6, 1996.
L. E. Derby, Tennis, P., and Jick, H., Sudden unexplained death among subjects with refractory epilepsy, Epilepsia, vol. 37, pp. 931-5, 1996.
S. Donovan, The Use of the General Practice Research Database (Gprd) to Examine Potential Links between Antidepressant Medication and the Incidence of Suicide, Drug Information Journal, vol. 30, pp. 785-792, 1996.
D. Henry, Lim, L. L., Rodriguez, L. A. Garcia, S. Gutthann, P., Carson, J. L., Griffin, M., Savage, R., Logan, R., Moride, Y., Hawkey, C., Hill, S., and Fries, J. T., Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis, Bmj, vol. 312, pp. 1563-6, 1996.
S. S. Jick, Dean, A. D., and Jick, H., Antidepressants and suicide, Bmj, vol. 310, pp. 215-8, 1995.
I. Nazareth, King, M., and Davies, S., Care of schizophrenia in general practice: the general practitioner and the patient, Br J Gen Pract, vol. 45, pp. 343-7, 1995.
T. Lancaster, Surman, G., Lawrence, M., Mant, D., Vessey, M., Thorogood, M., Yudkin, P., and Daly, E., Hormone replacement therapy: characteristics of users and non-users in a British general practice cohort identified through computerised prescribing records, J Epidemiol Community Health, vol. 49, pp. 389-94, 1995.
H. Jick and Derby, L. E., A large population-based follow-up study of trimethoprim-sulfamethoxazole, trimethoprim, and cephalexin for uncommon serious drug toxicity, Pharmacotherapy, vol. 15, pp. 428-32, 1995.
L. A. Garcia Rodriguez, Mannino, S., and Wallander, M. A., Ocular safety of antiulcer drugs, Lancet, vol. 345, pp. 1059-60, 1995.
H. Jick, Jick, S. S., Gurewich, V., Myers, M. W., and Vasilakis, C., Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptives with differing progestagen components, Lancet, vol. 346, pp. 1589-93, 1995.
H. Jick, Myers, M. W., and Dean, A. D., The risk of sulfasalazine- and mesalazine-associated blood disorders, Pharmacotherapy, vol. 15, pp. 176-81, 1995.
[Page last reviewed 5 July 2021]