Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
05/04/2023	Dementia and serious health outcomes: a cohort and case control study investigating psychological distress as a risk factor
05/04/2023	Background rates of serious adverse events to contextualise safety assessments in clinical trials and non-interventional studies in adolescent and adult patients with severe asthma: A Data Analysis and Real World Interrogation Network (DARWIN EU) study
05/04/2023	The risk of acute infection in new users of antihypertensive drugs: a cohort study
04/04/2023	Trends in general practice skill mix: observational analysis using routine health data
04/04/2023	Paediatric Otorrhoea: Understanding the burden of disease
31/03/2023	Characterisation of acute and long-term COVID-19 symptoms and complications in primary care electronic health records from the UK
28/03/2023	Descriptive analysis of primary care demand in England
28/03/2023	Estimating the incidence and prevalence of Gender-Based Violence as well as its outcomes during the life course
28/03/2023	Evaluation of the Representativeness of CPRD Data for Suitability to Conduct Clinical Epidemiological Studies in Patients with Lung Cancer in England : A Feasibility Study
28/03/2023	Preventing steroid harms in people with polymyalgia rheumatica in UK primary care
28/03/2023	A longitudinal analysis investigating cardiovascular outcomes in people with type 2 diabetes by treatment class in England.
28/03/2023	Prescribing of allopurinol among different ethnic groups: feasibility for a genetic study.
28/03/2023	Key drivers of mental health illnesses among women with Polycystic Ovary Syndrome: a retrospective study.
28/03/2023	Use of menopausal hormone therapy and risk of fractures: nested case-control study using CPRD
27/03/2023	Evaluation of ethnicity recording and ascertainment methods using linked data from the UKs Clinical Practice Research Datalink and Hospital Episode Statistics
27/03/2023	Management of contraception after pregnancy by primary care in England
27/03/2023	Development and validation of Rheumatoid Arthritis PredIction moDel using primary care health records (RAPID)
27/03/2023	CHARIOT: A Cardiovascular Health Assessment and Risk-based Intervention Optimisation Tool embedded within the patient-facing health record
23/03/2023	Multi-morbidity, Inequality and Use of and Access to Health Care (MICA)
23/03/2023	Feasibility study on data availability of early life factors associated with asthma.