Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
31/03/2016	Post-marketing study of ropinirole prolonged release tablets in Parkinson's disease: Evaluation outcomes associated with long term use of Ropinirole-PR using the UK clinical practice research datalink (UK-CPRD)
24/03/2016	Feasibility of using physician notes and discharge letters to assess potential benefits of early identification of subjects with cognitive deterioration
24/03/2016	Disease clusters and multimorbidity patterns: a UK population cohort study
24/03/2016	Hyperglycaemia and early detection of pancreatic cancer
24/03/2016	Evaluating the impact of NICE guidelines for suspected cancers in respect of diagnostic interval and other outcomes
17/03/2016	The risk of cardiovascular related death following cytomegalovirus (CMV) infection in England: an open cohort study using data from the Clinical Practice Research Datalink (CPRD)
14/03/2016	Low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride and diverse non-cardiovascular diseases: a large population-based cohort study using CALIBER dataset
14/03/2016	Benign and Malignant Tumors in Patients with Myotonic Dystrophy Type I
14/03/2016	Child Outcome REVIEW Programme: Chronic Disability
14/03/2016	Treatment of uncomplicated mild hypertension in Primary Care
11/03/2016	The characteristics of rheumatoid arthritis patient organisation members and online community members with rheumatoid arthritis compared to the general rheumatoid arthritis population
10/03/2016	Investigating the utility of blood pressure variability in cardiovascular risk prediction
09/03/2016	Predictors of complications of venous thromboembolism
08/03/2016	Natural history, characteristics, and treatment patterns in patients with primary biliary cirrhosis and cholestatic pruritis
25/02/2016	Predicting first admission and readmission in heart failure patients
25/02/2016	Risks and benefits of bisphosphonate use in patients with chronic kidney disease: a population-based cohort study
25/02/2016	Validity of UK general practice prescribing safety indicators in predicting adverse events
24/02/2016	The last year of life in COPD: prognostication, preparation, palliation
23/02/2016	Risk of hypoglycaemia in users of sulphonylureas with renal impairment: a population-based cohort study
23/02/2016	Epidemiology of venous thromboembolism in patients with active cancer: a population-based cohort study