Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
29/10/2015	Predicting individual risk of future hip and knee replacement for osteoarthritis
28/10/2015	Disease burden of diabetes patients with high dose insulin treatment in CPRD
27/10/2015	Prediagnostic presentations and comorbidities of multiple sclerosis in primary care: a case-control study
27/10/2015	Morbidity among HIV-positive people in England: a cross-sectional, population-based CALIBER study
27/10/2015	Determinants of Zoster vaccination acceptance in people eligible for NHS shingles vaccination programme
19/10/2015	Usage Patterns of Selected Systemic NSAIDs (Including Diclofenac): A Retrospective Cohort Study
14/10/2015	The association between lansoprazole and tuberculosis disease; a primary care based cohort study
14/10/2015	A study of multifactorial intervention in type 2 diabetes and chronic kidney disease
12/10/2015	An Epidemiological Study Examining the Risk of Serious Adverse Effects Associated with Corticosteroid Therapy in Rheumatoid Arthritis (RA) Patients
12/10/2015	Estimating the healthcare use and costs of children born to pregnant smokers
12/10/2015	The efficacy and safety of concomitant treatment with telmisartan, candesartan or bisoprolol in combination with amlodipine in patients with essential arterial hypertension: outcomes in real world practice
08/10/2015	The risk of depression and suicidality in patients with psoriasis, psoriatic arthritis or ankylosing spondylitis: a retrospective United Kingdom database analysis
08/10/2015	Incidence of corticosteroid related adverse events in inflammatory musculoskeletal conditions
06/10/2015	Effects of pulmonary rehabilitation on exacerbation number and severity in people with Chronic Obstructive Pulmonary Disease
06/10/2015	Investigation of long-term outcomes and healthcare utilisation of survivors of critical illness
06/10/2015	What is the burden of foot and ankle pain in the general population of the United Kingdom as recorded by General Practitioners?
06/10/2015	The association between Huntington's disease and cancer before and after the Huntington's diagnosis - a two-phase study
05/10/2015	An evaluation of the epidemiology and burden of illness of congenital adrenal hyperplasia in the United Kingdom
02/10/2015	Statins for Prevention of Cardiovascular Disease in Older Primary Care UK Patients
02/10/2015	Developing insights into treatment of chronic/diabetic kidney disease (CKD/DKD) using real world data