Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
20/07/2016	Characteristics of patients initiating empagliflozin or other non-insulin glucose lowering drugs in the United Kingdom
19/07/2016	Unsupervised clustering and topological analysis of Type-2 Diabetes and prediabetes patients in CALIBER using clinical data from electronic medical records
14/07/2016	Incidence and risk factors for paediatric acute kidney injury in the UK
12/07/2016	Linaclotide Utilisation Study in the UK - Extended Feasibility Counts
11/07/2016	Cancer and risk of herpes zoster - case-control study in the Clinical Practice Research Datalink
11/07/2016	Age- and lifestyle-related chronic disease and causes of mortality among adults with cerebral palsy in the United Kingdom.
07/07/2016	Profiling the natural history of Crigler-Najjar syndrome using the Clinical Practice Research Datalink
06/07/2016	Stability of blood eosinophils in COPD and controls and the impact of eosinophil count, age, gender and smoking status
06/07/2016	Sequelae of gastrointestinal infections: incidence, risk factors, and economic impact on primary and secondary care settings.
06/07/2016	Towards An Understanding Of Persistence, Switching, And Adherence With Medications For Over-Active Bladder:A Retrospective Observational Study In UK Clinical Practice
05/07/2016	Risk of stroke following discontinuation of oral anticoagulant treatment for atrial fibrillation: a cohort study
05/07/2016	Patient Characteristics Associated With Initiation Of Insulin Glargine Among Patients With Type 1 Or Type 2 Diabetes Mellitus In The United Kingdom
05/07/2016	Statin use and incident hand osteoarthritis: A propensity-score matched sequential cohort study
05/07/2016	Androgen Deprivation Therapy and Risk of Dementia
04/07/2016	Safety study to quantify the risk of ulceration (including all sites of occurrence), and related events (including perforations, fistula, abscess and bleeding) and death among patients treated with nicorandil with and without diverticular disease
30/06/2016	Assessment of Metformin Use Pattern in UK using CPRD
29/06/2016	Generalizability of Clinical Trial Results: Value of Individual Data versus Aggregate Data
29/06/2016	Characterisation and cardiovascular risk profile of type 2 diabetes mellitus patients according to initiation of antidiabetic medications
29/06/2016	Eligibility for Lung volume reduction surgery for COPD in the UK
29/06/2016	Long-term severe non-dermatological outcomes in eczema