Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
29/06/2016	Pharmacoepidemiology of pancreatin use in non-cystic fibrosis patients and comparison of all-cause mortality with that of their matched controls
29/06/2016	Comparative effectiveness of lansoprazole and omeprazole for the prevention of gastrointestinal bleeding and malignancy
22/06/2016	Immunosuppressive therapy and Parkinson's disease risk
21/06/2016	What is the occurrence of clinically diagnosed coeliac disease and dermatitis herpetiformis in the UK today? A population based cohort study utilising electronically linked health records.
21/06/2016	Diabetes, use of metformin and the risk of meningioma
21/06/2016	Three months versus 28 day prescriptions: a retrospective analysis of CPRD data to determine differences in the cost of drug wastage, dispensing fees and prescriber time
16/06/2016	Oral anticoagulants for atrial fibrillation and the risk of fractures
16/06/2016	The association between bariatric surgery and renal outcomes
14/06/2016	Use of parenteral corticosteroids and risk of type 2 diabetes mellitus.
14/06/2016	The characteristics and treatment patterns of Parkinson's disease patients in the UK
14/06/2016	Descriptive assessment of the Hospital Treatment Insights database and its link to the Clinical Practice Research Datalink for research on antibiotic dispensing in English hospitals
14/06/2016	GLP-1 agonists and the risk of breast cancer in patients with type 2 diabetes
09/06/2016	β-blocker effects on the association of hypoglycaemia with cardiovascular and all-cause mortality
09/06/2016	A retrospective database study of the prescribing of zonisamide in UK general practice: a drug utilisation study as part of post marketing safety surveillance.
06/06/2016	Cataract in patients with diabetes mellitus
06/06/2016	Estimating the risk of acute kidney injury associated with use of diuretics and renin angiotensin aldosterone system blockers in CPRD
06/06/2016	Using pharmacoepidemiology to test medications associated with altered risk of breast cancer progression identified from connectivity mapping
03/06/2016	A Joint Drug Utilisation Study (DUS) of valproate and related substances, in Europe, using databases
02/06/2016	PASS in patients with type 2 diabetes mellitus to assess the risk of acute liver injury, acute kidney injury and chronic kidney disease, severe complications of urinary tract infection, genital infections, and diabetic
02/06/2016	Development of small population prevalence model for heart failure