Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
16/08/2016	External validation of risk scores for dementia in the CPRD population
16/08/2016	Cohort study on the uptake of pharmacological treatments to prevent cardiovascular diseases in UK cancer survivors versus general population from 2005-2013.
15/08/2016	Proton pump inhibitors and kidney disease: a self-controlled case series and cohort study
15/08/2016	Comprehensive ascertainment of bleeding in patients prescribed different combinations of dual antiplatelet therapy (DAPT) and triple therapy (TT, DAPT plus an anticoagulant) after coronary interventions in the UK (The ADAPTT Study).
02/08/2016	Comparison of information on diagnosis of musculoskeletal outcomes in the Million Women Study cohort and CPRD-GOLD: a record linkage study
02/08/2016	Obstructive airway disease phenotype discovery using cluster analysis techniques in CPRD
02/08/2016	Metabolic syndrome and risk of meningioma - population-based case-control analysis
01/08/2016	Comparison of Health Economic Outcomes for Patients with Asthma who switch from Seretide to flutiform or Fostair using the CPRD-HES Linked Database
01/08/2016	Use and costs of primary care consultations and prescription medications in relation to body mass index in middle-aged UK women
01/08/2016	Can Novel Integrated Risk Schemes Change Treatment Decisions and Improve Health Outcomes in the Year after a Diagnosis of Atrial Fibrillation? An Individual-Based Simulation
29/07/2016	Trimethoprim and sudden death in patients over 65 years with urinary tract infection
28/07/2016	Androgen Deprivation Therapy for Prostate Cancer and the Risk of Hospitalisation for Community-Acquired Pneumonia
28/07/2016	An analytical framework for increasing the efficiency and validity of research using primary care databases
28/07/2016	Safety and associated costs of glucocorticoid therapy for the treatment of chronic inflammatory diseases
28/07/2016	Association between cardiovascular disease and zoster risk - case-control study in the Clinical Practice Research Datalink
25/07/2016	Proton pump inhibitor use and risk of developing Alzheimer's disease or vascular dementia
20/07/2016	Use of Nalmefene (Selincro) in the UK: Cohort design using longitudinal electronic medical records (EMR)
20/07/2016	Estimation of undiagnosed lysosomal acid lipase deficiency in a paediatric population: a UK database study
20/07/2016	Risk of major bleeds associated with the use of direct oral anticoagulants in venous thromboembolism
20/07/2016	Longitudinal Analyses of Body Mass Index and Risk of Parkinson's Disease in CPRD