Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
14/11/2016	Effect of statin therapy in older patients after a first cerebrovascular event or myocardial infarction, a population based cohort study in the CPRD
14/11/2016	Investigating the cost effectiveness of alternative oral antiplatelet regimens in patients with type 2 diabetes in England.
10/11/2016	Benefits of high dose ICS in patients with asthma and high blood eosinophil counts
09/11/2016	Diagnosis and treatment of dementia in primary care in the UK
08/11/2016	Gender differences in Chronic Obstructive Pulmonary Disease: baseline characteristics, progression, and exacerbations in the United Kingdom's Clinical Practice Research Datalink
07/11/2016	Is Hydroxychloroquine associated with decreased mortality among people with Rheumatoid Arthritis
07/11/2016	20 year trends for prevalence and incidence of Resistant Hypertension in the United Kingdom and prognosis in adults with hypertension
07/11/2016	Blood eosinophil count and prospective asthma disease burden
03/11/2016	Metformin and the incidence of lymphoid malignancies in patients with type 2 diabetes
29/10/2016	Investigating safety of 'metabolically healthy obesity' and sustainability from community and tertiary based databases in the UK
28/10/2016	Annual Healthcare Resource Use and Costs for Eczema in Children: A Cost of Illness Study for the English NHS
24/10/2016	Trends in NHS prescribing of dual NRT (DNRT) and varenicline in pregnancy and effects on infants
24/10/2016	Drug utilization study of dexamfetamine in European countries
18/10/2016	Use of novel regression discontinuity design to investigate safety of statins in the UK Clinical Practice Research Datalink
18/10/2016	Impact of hospital admission upon patterns of primary care prescribing
18/10/2016	Incidence, prevalence, mortality and health-service use among people with systemic sclerosis (scleroderma) in the UK Clinical Practice Research Datalink
18/10/2016	Clinical effectiveness of combining two drugs versus monotherapy as initial treatment strategy in hypertension - a matched cohort study in CPRD
18/10/2016	Primary Care and Access To Surgical Treatment For Women With Urinary Incontinence
17/10/2016	Changes in lung function (FEV1) over time in a primary care COPD cohort
14/10/2016	What are the long-term health outcomes in low birth weight and premature babies born with chronic lung disease who are discharged home on oxygen?