Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
23/03/2023	Treatment Patterns, Healthcare Resource Utilization and Costs in Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in England
23/03/2023	Feasibility study on data availability of early life factors associated with asthma.
23/03/2023	Dipeptidyl peptidase-4 inhibitors and the risk of gallbladder and bile duct diseases among patients with type 2 diabetes
23/03/2023	Multi-morbidity, Inequality and Use of and Access to Health Care (MICA)
21/03/2023	Gabapentinoid Use and the Risk of Fractures in Patients with Inflammatory Arthritis: a nested Case-Control Study in the Clinical Practice Research Datalink Aurum.
14/03/2023	Blood pressure and adverse cardiovascular outcomes in older people with chronic kidney disease and type 2 diabetes
14/03/2023	Clinical implications of intentional weight loss in patients with type 2 diabetes (T2D): a retrospective cohort study using the UK Clinical Practice Research Datalink (CPRD) Aurum database
13/03/2023	The epidemiology, demographics and socio-economic aspects of patients with myasthenia gravis and Lambert-eaton syndrome.
13/03/2023	Improving management of non-alarm symptoms of bladder and kidney cancer: a case-control study and health economic assessment
13/03/2023	Epidemiology and burden of imminent subsequent fractures in postmenopausal women
06/03/2023	Associations of clusters of adults with multimorbidity with clinical outcomes and healthcare utilisation
06/03/2023	Glucagon-like peptide 1 receptor agonists and sodium-glucose cotransporter 2 inhibitors and the prevention of liver complications of non-alcoholic fatty liver disease among patients with type 2 diabetes
06/03/2023	Demographic groups and prodromal symptoms in rheumatoid arthritis (RA) in primary care: An analysis to support health equity in big-data clinical prediction models.
06/03/2023	Investigating the risk and risk factors of suicide following a traumatic brain injury in the general population
02/03/2023	Impact of the COVID-19 pandemic on mental health diagnoses and prescriptions in the UK
02/03/2023	Arterial and Venous Thromboembolism in patients with Hereditary Angioedema (AVeTHA) study
02/03/2023	Changes in prevalence and incidence of breast, colorectal, lung and prostate cancer, and treatment side effects, before and after the COVID-19 pandemic
28/02/2023	EXAcerbations of Chronic Obstructive Pulmonary Disease (COPD) and their OutcomeS on CardioVascular diseases (EXACOS-CV) study: an observational cohort study in the UK
28/02/2023	The impact of COVID-19 vaccination on the long-term effects of COVID among adults in England diagnosed with COVID prior to Omicron dominance
28/02/2023	Characterising similarities and differences in Type 2 Diabetes, Overweight&Obese, and Non-Alcoholic SteatoHepatitis (NASH) patients and their risk of adverse clinical events: an observational cohort study in the United Kingdom