Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
24/06/2021	Identifying how best to identify pneumonia and differentiate pneumonia from asthma and chronic obstructive pulmonary disease exacerbations in routine primary care data
21/06/2021	Demographic, socioeconomic, temporal, and spatial patterns in the prescription of contraceptives within UK primary care
21/06/2021	Incident Neutropenia in New Users of Cyclooxygenase-Inhibitors: An Observational Cohort Study
17/06/2021	TRial to Assess Implementation of New research in a primary care Setting (TRAINS): a pragmatic cluster randomised controlled trial of an educational intervention to promote prescription uptake in General Practitioner Practices
15/06/2021	Mortality rates, risk factors and treatment patterns in patients diagnosed with moderate-to-very-severe chronic obstructive pulmonary disease in England: a retrospective observational study using CPRD data
11/06/2021	Optimal dynamic treatment regimes for the management of chronic obstructive pulmonary disease (COPD)
10/06/2021	Prescription of blood pressure lowering and lipid lowering treatment in the UK and New Zealand: a cross sectional study
10/06/2021	Epidemiology of gout, its treatment and comorbidities - a prospective cohort study using data from Clinical Practice Research Datalink (CPRD)
10/06/2021	Does ethnicity affect the recognition of palliative care needs? An observational retrospective cohort study
09/06/2021	Cost-effectiveness of osteoporotic fracture risk assessment in people with intellectual disabilities
01/06/2021	Effectiveness of vaccination policies and current treatment stratification approaches for pneumonia: A regression discontinuity analysis
28/05/2021	Prevalence, prediction, and health outcomes of cardioprotective medication reduction in the older UK population
27/05/2021	Prevalence, Incidence, and healthcare burden of generalised pustular psoriasis, palmoplantar pustulosis, and plaque psoriasis in England
27/05/2021	Retrospective study estimating the incidence of alcoholic hepatitis in the United Kingdom
26/05/2021	Comparative effects of different antidiabetic treatments on COVID-19 mortality and vascular outcomes
26/05/2021	Identifying trends and causes of hospitalisations in people with and without the top 5 chronic conditions: a population-based study
26/05/2021	Investigating the effect of influenza vaccine on acute cardiovascular events by cardiovascular risk status
25/05/2021	Time to insulin initiation among second-line antidiabetics in a cohort of patients with type 2 diabetes
24/05/2021	The impact of learning disabilities on control of type 2 diabetes risk factors and outcomes in UK primary care
24/05/2021	Pharmacological treatments associated with increased or decreased risk of developing age-related macular degeneration: signal detection