Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
03/09/2021	Dose distributions of the injectable glucagon-like peptide-1 receptor agonists dulaglutide and semaglutide in patients with type 2 diabetes in UK primary care
03/09/2021	How many UK patients developed kidney failure since the year 2000? What treatments did they receive and what were their health outcomes?
03/09/2021	UKPREG: UKPREGnancy study - a longitudinal international registry-based cohort study of pregnancy and heart disease
27/08/2021	COVID-19 and incidence of venous thromboembolism (VTE) in the UK general population
27/08/2021	Clinical outcomes from robotic colorectal surgery in England: a national study using routinely collected data
27/08/2021	Association between degree of weight loss and reduction in risk of developing obesity related complications in adults living with obesity
27/08/2021	Evaluating treatment patterns of venous thromboembolism patients in primary care
27/08/2021	Analysis of the Clinical Practice Research Datalink (CPRD Gold + Aurum) and Hospital Episode Statistics (HES) to provide real world evidence on disease progression and the burden of uncomplicated urinary tract infection (uUTI)
27/08/2021	Parkinson's Disease in minority ethnic groups: understanding phenotypical traits and differences in outcomes to inform pathways of care
27/08/2021	Characterization of ezetimibe use in the United Kingdom: a retrospective database study
27/08/2021	Evaluating the performance of cutting-edge statistical methods in reducing confounding bias using plasmode simulations of electronic health record data
20/08/2021	Feasibility study exploring trial population eligibility criteria and occurrence of outcomes to inform CV trial programme
17/08/2021	The Impact of COVID-19 on care for UK patients with chronic obstructive pulmonary disease (COPD) and patients with asthma
12/08/2021	Assessing the clinical and economic burden among patients with Clostridium Difficile Infection and recurrent Clostridium Difficile Infections: A real-world evidence study
12/08/2021	Incidence and prevalence of obesity, pre-diabetes, type 1 and 2 diabetes and complications and risk factors in people younger than 40 years in the UK.
10/08/2021	Respiratory infection related cardiovascular disease: a prognostic modelling and causal inference study
06/08/2021	Concomitant use of biphasic insulin aspart and glucagon-like peptide-1 receptor agonist compared to modern basal insulin combined with glucagon-like peptide-1 receptor agonist: effect on glycaemic control in type 2 diabetes patients
03/08/2021	Differences in morbidity and mortality in men and women with chronic obstructive pulmonary disease and peripheral arterial disease
03/08/2021	Epidemiology and healthcare resource utilisation associated with Duchenne muscular dystrophy
30/07/2021	Incretin-based drugs and the incidence of prostate cancer among patients with type 2 diabetes