Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
30/07/2021	Event Rates and Risk factors for Cardiovascular Events in a United Kingdom Population with Hypertension
30/07/2021	Determining treatment pathways, healthcare resource usage, and associated costs of patients with Myasthenia Gravis in England
23/07/2021	A risk prediction model to predict incident heart failure (RiskHF): derivation and validation cohort study
23/07/2021	Identifying the clinical risks associated with COVID-19 in patients with congenital heart disease and associated co-morbidities
20/07/2021	Event Rates and Risk Factors for Atherosclerotic Cardiovascular Disease Events in High-Risk Primary Prevention and Atherosclerotic Cardiovascular Disease Populations in United Kingdom
14/07/2021	Alternative Confounding Control Approaches for the Prevalent New User Study Design: An Empirical Example Assessing the Effects of Antidiabetic Drug Exposure (sulfonylureas and GLP-1 analogs) on Hospitalization for Heart Failure
12/07/2021	Evaluation of the real-world safety of angiotensin-converting enzyme inhibitors on the risk of lung cancer
09/07/2021	Managing cardiovascular disease and risk in Covid-19 patients in primary care medicine
09/07/2021	Trends in primary care prescribing of benzodiazepines, antipsychotics and beta-blockers for anxiety.
09/07/2021	An evaluation of the prevalence, epidemiology and burden of illness of bone and joint infections in the United Kingdom: a retrospective observational cohort study
09/07/2021	Risk of Venous Thromboembolism After Knee, Hip or Shoulder Replacement: A Retrospective Cohort Study Using Linked Hospital and Primary Care Data
07/07/2021	The effect of increasing physician workload on the choice of referrals to secondary care units and lab tests
06/07/2021	Age-specific mortality rates of males diagnosed with Duchenne Muscular Dystrophy.
05/07/2021	Estimating national and local prevalence of mental health conditions during perinatal period in England: an exploratory study
01/07/2021	Socio-economic inequalities in prevalence and management of long-term conditions in primary care: a descriptive study
01/07/2021	Development of a Pregnancy Register in the CPRD Aurum database.
01/07/2021	Antipsychotics and risk of falls in people with Alzheimer's Disease and agitation. A self-controlled case series study and cohort study
28/06/2021	Living with dementia: understanding the prevalence of young-onset dementia
28/06/2021	Event Rates and Risk Factors for Cardiovascular Events in a Population with an Acute Coronary Syndrome Hospitalization in the United Kingdom
28/06/2021	Trends in remote GP consultations and the impact of remote consultations on antibiotic prescribing of antibiotics pre- and during COVID - an observational study