Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
20/09/2021	Real-World Open Angle Glaucoma (OAG) Disease Management, Treatment Patterns, Resource Utilization, and Outcomes from Primary Care through to Secondary Care in the UK Setting
20/09/2021	Understanding the contribution of influenza vaccines to antibiotic prescribing in the UK population: A longitudinal analysis
20/09/2021	Statin Treatment Options during vaccination against inFLUenza (STOPFlu) : a observational study of the interaction between statins and influenza vaccination
20/09/2021	Early warning score for Autism Spectrum Disorder using real-world data
20/09/2021	Effects of the COVID-19 pandemic on primary care recorded anxiety and depression, and psychotropic prescribing.
17/09/2021	Comparative effectiveness of second line glucose lowering therapies on preserving renal function in patients with type 2 diabetes
17/09/2021	Characterising surgery for wrist arthritis and its outcomes
16/09/2021	Cohort monitoring of Adverse Events of Special Interest and COVID-19 diagnoses prior to and after COVID-19 vaccination
16/09/2021	Describing causes of mortality in different subpopulations of people with Chronic Obstructive Pulmonary Disease and determining factors that may be associated with specific causes of death
16/09/2021	Non-invasive tests as prognostic biomarkers of liver events, cardiovascular events and all-cause mortality in individuals with obesity and or type 2 diabetes living in the United Kingdom: a longitudinal cohort study
10/09/2021	Pregnancy induced hypertension, gestational diabetes, and the risk of chronic kidney disease: A population-based study using the Clinical Practice Research Datalink.
10/09/2021	Healthcare resources utilisation and associated costs of adult Attention deficit hyperactivity disorder in England: A retrospective database study
10/09/2021	Descriptive analysis of trends in health care use in England by ethnicity and deprivation over the austerity period culminating in the COVID-19 pandemic
10/09/2021	Predicting Psoriatic Arthritis (PREDIPSA) - Dynamic modelling of primary care health-records for earlier diagnosis of psoriatic arthritis: a population-based study
06/09/2021	Impact of prompt versus delayed initiation of single-inhaler triple therapy among patients with Chronic Obstructive Pulmonary Disease in England in real-world primary and secondary care settings
06/09/2021	A study to assess the feasibility of using CPRD-HES linked data to investigate treatment of anemia in pregnancy and postpartum using oral and intravenous iron
06/09/2021	The impact of painful musculoskeletal conditions on outcomes of dementia
06/09/2021	Preventing Unscheduled Hospitalisations from Asthma: a retrospective cohort study using routine primary and secondary care data in the UK (The PUSH-Asthma Study)
06/09/2021	Comparative effectiveness of combination therapies on mortality in chronic obstructive pulmonary disease (COPD)
06/09/2021	Feasibility study of the data characterisation of the Innovative Medicines Initiative ConcePTION common data model applied to CPRD GOLD