Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
20/05/2019	Distribution of risk of cardiovascular diseases and fractures among elderly women with a recent fracture in CPRD: a cross-sectional study
20/05/2019	The effect of non-pharmacological asthma management tools on preventing asthma exacerbations in children and adults in England
15/05/2019	Hypertension detection and cardiovascular outcomes: a retrospective cohort study using data from the Clinical Practice Research Datalink database
15/05/2019	Psoriasis and the risk of cancer incidence and mortality: a cohort study
09/05/2019	Development and internal validation of prognostic scores for risk of diabetic foot ulceration
08/05/2019	Determinants of blood pressure lowering treatment prescribing for primary prevention: a cohort study in UK primary care
08/05/2019	Clinical course of non-alcoholic fatty liver disease/non-alcoholic stateohepatitis in the United Kingdom: a feasibility study using the clinical practice research datalink and hospital episode statistics
08/05/2019	Concomitant use of oral glucocorticoids and proton pump inhibitors, and risk of osteoporotic fractures among patients with rheumatoid arthritis: a population-based cohort study
03/05/2019	An evaluation of patient outcomes for Type 2 Diabetes Mellitus (T2DM) patients prescribed dipeptidyl peptidase-4 (DPP4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors or Sulphonylureas (SUs) at first intensification
03/05/2019	SGLT-2 inhibitors and the risk of venous thromboembolism
01/05/2019	Does anticoagulant choice affect the risk of incident dementia among individuals with atrial fibrillation? A cohort study using linked CPRD-HES data
01/05/2019	A comparison of the risk of cardiovascular events and cancers in the ASCEND study cohort and people with diabetes identified using electronic primary care records: a cohort study
01/05/2019	Incidence and clinical management of common mental illnesses, and antecedent factors associated with self-harm, among children and adolescents in a UK primary care cohort
01/05/2019	The Use of Anti-Estrogens and the Risk of Parkinson’s Disease
29/04/2019	International migrant healthcare access in England: a population-based linked cohort study of healthcare resource utilisation and mortality amongst international migrants registered with primary care services
26/04/2019	Prediction of imminent fracture risk in new users of oral bisphosphonates or recently fractured subjects: a multinational European real-world cohort study
26/04/2019	Evaluation of referral system and outcome among patients with breast and colorectal conditions
23/04/2019	Defining diseases clusters in adults with multimorbidity
18/04/2019	Describing the characteristics of patients who die of COPD with no evidence of prior diagnosis
18/04/2019	Safety of five years of pertussis vaccination in pregnancy in England: a cohort study