Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
20/08/2018	Comparative Safety of the Sodium Glucose Co-transporter-2 (SGLT2) Inhibitors in Patients with Type 2 Diabetes
20/08/2018	Investigating associations between environmental factors and exacerbations of COPD and asthma
14/08/2018	Do systemic antibiotics affect the effectiveness of chemotherapy for malignant cancers? - A cohort study based on CPRD and Cancer Registry data
14/08/2018	Variation in patient pathways and hospital admissions for exacerbations of COPD: linking the National Asthma and COPD Audit Programme (NACAP) with CPRD data
09/08/2018	An assessment of CPRD Aurum data quality
09/08/2018	Testing people with type 2 diabetes, hypertension or chronic kidney disease in United Kingdom primary care
09/08/2018	Is polypharmacy associated with death or ischemic stroke in individuals newly diagnosed with atrial fibrillation? A prognostic cohort study using data from The Clinical Practice Research Datalink (CPRD)
09/08/2018	Characterising the renal function of newly diagnosed non-valvular atrial fibrillation patients
08/08/2018	Fractures in people with intellectual disabilities: comparison with the general population and development of a fracture risk calculator specific to these patients
07/08/2018	Examining treatment patterns of antidepressant and antipsychotic prescriptions; and serious adverse events and the associated economic cost of antipsychotic drug use in people with dementia
07/08/2018	Assessing the effect of switching from an inhaler regimen containing inhaled corticosteroid to one without in a real-world COPD population
07/08/2018	Relationship between Body Mass Index (BMI) trajectory and the risk of cardiovascular disease and diabetes among overweight and obese people: A UK Primary Care-based cohort study
07/08/2018	M.A.P.P.E.D. IMproving the Accuracy of Psychosis PrEDiction using primary-care consultation data
01/08/2018	A study on the epidemiology of tinnitus in the United Kingdom
01/08/2018	Defining patient groups at short-term high risk of fracture and evaluating current practice of osteoporosis treatment and rate of different fractures and cardiovascular events in these patient groups
01/08/2018	Asthma and Type 2 Co-morbidities
01/08/2018	Differences in Heart Failure Care and Survival: A Comparison between United Kingdom, Sweden, Netherlands and Spain using Linked Electronic Health Care Records
01/08/2018	Deriving Risk Equations for Complications of Type 2 Diabetes for the UK CPRD population
01/08/2018	Bile acid sequestrants and risk of selected age-related diseases
01/08/2018	Impact of subsequent major adverse cardiovascular events on mortality in a post-myocardial infarction population: a retrospective UK database analysis