Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort ascending Title
Gout and Neurodegenerative Disorders: A retrospective cohort study in the Clinical Practice Research Datalink
Effect of major common infections on the incidence of post-stroke dementia: a cohort study using the UK Clinical Practice Research Datalink
To establish the causal roles of environmental factors on exacerbations of COPD
Utilization of Standard and Target-Specific Oral Anticoagulants among Adults in the United Kingdom with Incident Non-Valvular Atrial Fibrillation
The last year of life in COPD: prognostication, preparation, palliation
The role of systemic inflammatory diseases in long-term morbidity and mortality: a retrospective, matched-cohort study in the Clinical Practice Research Datalink
Development of an identification tool for patients over 65 years at risk of death or emergency hospital admission during cold weather.
Clinical effectiveness of combining two drugs versus monotherapy as initial treatment strategy in hypertension - a matched cohort study in CPRD
Prescribing of antidiabetic drug therapy and comparative incidence of outcomes associated with Type 2 Diabetes
Post-authorisation safety study to assess the risk of urinary tract malignancies in relation to empagliflozin exposure in patients with type 2 diabetes: a multi-database European study
What are the optimal cardiovascular risk assessment and treatment targets among patients diagnosed with specific inflammatory disorders?
Association between antineoplastic therapies and venous thromboembolism in patients with active cancer
Incidence of major bleeding events and ischaemic stroke among non-valvular atrial fibrillation patients in the UK