Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort ascending Title
04/05/2016 Androgen Deprivation Therapy for Prostate Cancer and the Risk of Anaemia
02/05/2016 Descriptive Epidemiology of Multimorbidity in Primary Care: A Cross-Sectional Study
02/05/2016 Treatment choice and outcomes associated with dry powder inhaler and Tiotropium Respimat monotherapy in COPD (chronic obstructive pulmonary disease) patients
28/04/2016 Premature mortality and non-fatal self-harm in patients diagnosed with Chronic Fatigue Syndrome
20/04/2016 Determinants of exacerbations of asthma
20/04/2016 Urinary tract infections in the elderly - care pathways and characteristics
20/04/2016 A Retrospective Descriptive Study of the Cohort of Type 2 Diabetes Mellitus Patients Initiating a Second-line Therapy in the United Kingdom Clinical Practice Research Datalink (CPRD) Database
20/04/2016 Assessing drivers of effectiveness and safety using real life data: anticoagulants as a case study
20/04/2016 A prevalence and incidence study of multimorbidity in the UK using the Clinical Practice Research Datalink (CPRD)
20/04/2016 The association between severe mental illness and chronic kidney disease: a cross sectional study
20/04/2016 Prescribing patterns of dependence forming medicines: Benzodiazepines, z-drugs, opioids and GABAergic drugs
19/04/2016 Characterization of patients with COPD by mepolizumab eligibility criteria
19/04/2016 Developing and validating a risk prediction model based on frailty syndrome using primary care data
19/04/2016 The epidemiology and treatment patterns of patients with Gastro-oesophageal reflux disease (GORD) in routine general practice.
19/04/2016 Association Between Blood Eosinophil Level and Exacerbation Risk in Patients with COPD
18/04/2016 Historical cohort study to evaluate undertreatment and disease outcomes for patients with coexisting Heart Failure and Chronic Obstructive Pulmonary Disease
11/04/2016 An epidemiological study of diabetes and diabetes-related morbidities in the UK children and young adults
10/04/2016 Vaccine effectiveness of the national rotavirus vaccination programme against acute gastroenteritis in England
10/04/2016 Hematological malignancies in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom.
30/03/2016 Post-marketing study of ropinirole prolonged release tablets in Parkinson's disease: Evaluation outcomes associated with long term use of Ropinirole-PR using the UK clinical practice research datalink (UK-CPRD)