Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
27/07/2018	A study of cardiovscular mortality and morbidity of patients with adrenal insufficiency
27/07/2018	Do NHS Health Checks improve patient's Diabetic Healthcare outcomes? A population-based study using the CPRD
24/07/2018	Determining the frequency of abnormal hepatic fibrosis measures and liver cirrhosis/decompensation in UK primary care
24/07/2018	Understanding the impact of the routine use of anti-diabetic (PPAR gamma)/anti-hyperlipidaemic (PPAR alpha) medication on risk of brain tumours and case fatality
23/07/2018	Evaluating effect modification using propensity score matching and disease risk score methods: an empirical study
23/07/2018	Long term impact of giving antibiotics before skin incision versus after cord clamping on children born by caesarean section: longitudinal study based on UK electronic health records
23/07/2018	Study of recovery in patients hospitalised with community acquired pneumonia using Clinical Practice Research Datalink (CPRD), linked to Hospital Episode Statistics
20/07/2018	Better Targeting of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease
20/07/2018	Serum cholesterol trajectories in the years prior to lymphoma diagnosis
20/07/2018	Dipeptidyl peptidase-4 inhibitors and the risk of bullous pemphigoid among patients with type 2 diabetes
20/07/2018	A retrospective cohort study using the Clinical Practice Research Datalink to assess the proportion of pregnancy outcomes, pregnancy-related events of interest, and infant events of interest in pregnant women and their infants
20/07/2018	Using electronic health records to assess effectiveness of national policy in dementia recognition in the UK
20/07/2018	Discovery and characterization of heart failure sub phenotypes using cluster analysis methods in CPRD
16/07/2018	Risk factors of cardiovascular disease amongst users of anti-osteoporosis therapy/ies, patients with osteoporosis, or those suffering a fracture in the UK NHS: a cohort study
16/07/2018	Use of renin angiotensin system inhibitors and incident treated depression, and nonfatal or fatal self-harm
16/07/2018	Correlation of forced expiratory volume in one second with mortality and resource use in patients with asthma
16/07/2018	Predicting risk of dementia using routine electronic health records
16/07/2018	Getting sustainable, person-centred musculoskeletal health intelligence from primary care electronic health record linkage and modelling: the PRELIM initiative – Work package 3
12/07/2018	Describing treatment and survival of children with congenital heart anomalies
12/07/2018	Describing monotherapy and combination use in male and female patients with treatment for Lower Urinary Tract Symptoms. A retrospective, observational study using the UK CPRD