| 2021 |
Increased mortality risk in patients with primary and secondary adrenal insufficiency
10.1210/clinem/dgab096
Authors: K. Ngaosuwan, D. Johnston, I. Godsland, J. Cox, A. Majeed, J. Quint, N. Oliver, S. Robinson |
| 2021 |
The increasing incidence and prevalence of hypereosinophilic syndrome in the United Kingdom
10.1002/iid3.495
Authors: G. Requena, J. Logie, D. Gibbons, J. Steinfeld, M. Van Dyke |
| 2021 |
Incretin-Based Drugs and Risk of Intestinal Obstruction Among Patients with Type 2 Diabetes
10.1002/cpt.2430
Authors: J. Faillie, H. Yin, O. H. Y. Yu, A. Herrero, R. Altwegg, C. Renoux, L. Azoulay |
| 2021 |
Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study
10.1016/s2589-7500(21)00017-0
Authors: K. Mansfield, R. Mathur, J. Tazare, A. Henderson, A. Mulick, H. Carreira, A. Matthews, P. Bidulka, A. Gayle, H. Forbes, S. Cook, A. Wong, H. Strongman, K. Wing, C. Warren-Gash, S. Cadogan, L. Smeeth, J. Hayes, J. Quint, M. McKee, S. Langan |
| 2021 |
Inequalities in incident and prevalent multimorbidity in England, 2004\textendash19: a population-based, descriptive study
10.1016/S2666-7568(21)00146-X
Authors: A. Head, K. Fleming, C. Kypridemos, P. Schofield, J. Pearson-Stuttard, M. O\textquoterightFlaherty |
| 2021 |
Infection-related complications after common infection in association with new antibiotic prescribing in primary care: retrospective cohort study using linked electronic health records
10.1136/bmjopen-2020-041218
Authors: B. van Bodegraven, V. Palin, C. Mistry, M. Sperrin, A. White, W. Welfare, D. Ashcroft, T. van Staa |
| 2021 |
Infectious Disease Burden and the Risk of Alzheimer\textquoterights Disease: A Population-Based Study
10.3233/jad-201534
Authors: A. Douros, C. Santella, S. Dell'Aniello, L. Azoulay, C. Renoux, S. Suissa, P. Brassard |
| 2021 |
Serum lipid trajectories in the years before a lymphoma diagnosis
10.1080/10428194.2021.1992618
Authors: J. Fortuny, E. Plana, J. Kaye |
| 2021 |
Sex, Age, and Socioeconomic Differences in Nonfatal Stroke Incidence and Subsequent Major Adverse Outcomes
10.1161/strokeaha.120.031659
Authors: R. Akyea, Y. Vinogradova, N. Qureshi, R. Patel, E. Kontopantelis, G. Ntaios, F. Asselbergs, J. Kai, S. Weng |
| 2021 |
Sex disparity in subsequent outcomes in survivors of coronary heart disease
10.1136/heartjnl-2021-319566
Authors: R. Akyea, E. Kontopantelis, J. Kai, S. Weng, R. Patel, F. Asselbergs, N. Qureshi |
| 2021 |
SGLT-2 inhibitors and the risk of hospitalization for community-acquired pneumonia: A population-based cohort study
10.1002/pds.5192
Authors: V. Brunetti, P. Reynier, L. Azoulay, O. H. Y. Yu, P. Ernst, R. Platt, K. Filion |
| 2021 |
Shorter and longer courses of antibiotics for common infections and the association with reductions of infection-related complications including hospital admissions
10.1093/cid/ciab159
Authors: V. Palin, W. Welfare, D. Ashcroft, T. van Staa |
| 2021 |
Is the SMART risk prediction model ready for real-world implementation? A validation study in a routine care setting of approximately 380 000 individuals
10.1093/eurjpc/zwab093
Authors: A. McKay, L. Gunn, B. Ference, J. Dorresteijn, G. Berkelmans, F. Visseren, K. Ray |
| 2021 |
Social determinants of pertussis and influenza vaccine uptake in pregnancy: a national cohort study in England using electronic health records
10.1136/bmjopen-2020-046545
Authors: J. Walker, C. Rentsch, H. McDonald, J. Bak, C. Minassian, G. Amirthalingam, M. Edelstein, S. Thomas |
| 2021 |
Statin prescription in patients with chronic obstructive pulmonary disease and risk of exacerbations: a retrospective cohort study in the Clinical Practice Research Datalink
10.1136/bmjopen-2021-050757
Authors: M. Smith, H. Ashdown, J. Sheppard, C. Butler, C. Bankhead |
| 2021 |
Statin treatment and LDL-cholesterol treatment goal attainment among individuals with familial hypercholesterolaemia in primary care
10.1136/openhrt-2021-001817
Authors: B. Iyen, R. Akyea, S. Weng, J. Kai, N. Qureshi |
| 2021 |
Statins After Ischemic Stroke in the Oldest: A Cohort Study Using the Clinical Practice Research Datalink Database
10.1161/strokeaha.120.030755
Authors: G. Lefeber, W. Knol, P. Souverein, M. Bouvy, A. de Boer, H. Koek |
| 2021 |
A study of cancer occurrence in users of mirabegron and antimuscarinic treatments for overactive bladder
10.1080/03007995.2021.1891035
Authors: K. Phiri, J. Hallas, M. Linder, A. Margulis, B. Suehs, A. Arana, S. Bahmanyar, V. Hoffman, C. Enger, L. Horter, I. Odsbu, M. Olesen, S. Perez-Gutthann, N. Kristiansen, K. Appenteng, S. de Vogel, J. Seeger |
| 2021 |
Suicide and other causes of death among working-age and older adults in the year after discharge from in-patient mental healthcare in England: matched cohort study
10.1192/bjp.2021.176
Authors: R. Musgrove, M. Carr, N. Kapur, C. Chew-Graham, F. Mughal, D. Ashcroft, R. Webb |
| 2021 |
Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting
10.1093/rheumatology/keab067
Authors: S. Swain, C. Coupland, C. Mallen, C. Kuo, A. Sarmanova, S. Bierma-Zeinstra, M. Englund, D. Prieto-Alhambra, M. Doherty, W. Zhang |
| 2021 |
Temporal trends in annual incidence rates for psychiatric disorders and self-harm among children and adolescents in the UK, 2003-2018
10.1186/s12888-021-03235-w
Authors: L. Cybulski, D. Ashcroft, M. Carr, S. Garg, C. Chew-Graham, N. Kapur, R. Webb |
| 2021 |
Tramadol versus Codeine and the Short-term Risk of Cardiovascular Events in Patients with Non-Cancer Pain: A Population-Based Cohort Study
10.1111/bcp.15099
Authors: L. Ou, L. Azoulay, P. Reynier, R. Platt, S. Yoon, R. Grad, K. Filion |
| 2021 |
Transforming and evaluating electronic health record disease phenotyping algorithms using the OMOP common data model: a case study in heart failure
10.1093/jamiaopen/ooab001
Authors: V. Papez, M. Moinat, S. Payralbe, F. Asselbergs, R. Lumbers, H. Hemingway, R. Dobson, S. Denaxas |
| 2021 |
Trends in leading causes of hospitalisation of adults with diabetes in England from 2003 to 2018: an epidemiological analysis of linked primary care records
10.1016/s2213-8587(21)00288-6
Authors: J. Pearson-Stuttard, Y. Cheng, J. Bennett, E. Vamos, B. Zhou, J. Valabhji, A. Cross, M. Ezzati, E. Gregg |
| 2021 |
Trends in new prescription of gabapentinoids and of coprescription with opioids in the 4 nations of the UK, 1993-2017
10.1111/bcp.14727
Authors: A. Rahman, J. Kane, F. Montastruc, C. Renoux |
| 2021 |
Trends in predominant causes of death in individuals with and without diabetes in England from 2001 to 2018: an epidemiological analysis of linked primary care records
10.1016/s2213-8587(20)30431-9
Authors: J. Pearson-Stuttard, J. Bennett, Y. Cheng, E. Vamos, A. Cross, M. Ezzati, E. Gregg |
| 2021 |
Trends in prescribing of nicotine replacement therapy to pregnant women in primary care in England
10.1093/ntr/ntab037
Authors: L. Szatkowski, L. Vaz, L. Fiaschi, L. Tata, T. Coleman |
| 2021 |
Trends in survival of older care home residents in England: A 10-year multi-cohort study
10.1016/j.socscimed.2021.113883
Authors: Espuny Pujol, R. Hancock, M. Morciano |
| 2021 |
Trends in the recording of anxiety in UK primary care: a multi-method approach
10.1007/s00127-021-02131-8
Authors: C. Archer, K. Turner, D. Kessler, B. Mars, N. Wiles |
| 2021 |
Triple Inhaler versus Dual Bronchodilator Therapy in COPD: Real-World Effectiveness on Mortality
10.1080/15412555.2021.1977789
Authors: S. Suissa, S. Dell'Aniello, P. Ernst |
| 2021 |
UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records
10.1186/s12889-021-10427-2
Authors: J. Walker, D. Grint, H. Strongman, R. Eggo, M. Peppa, C. Minassian, K. Mansfield, C. Rentsch, I. Douglas, R. Mathur, A. Wong, J. Quint, N. Andrews, J. Bernal, J. Scott, M. Ramsay, L. Smeeth, H. McDonald |
| 2021 |
Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population-based assessment
10.1002/prp2.848
Authors: Y. Yu, K. Filion, P. Reynier, R. Platt, O. H. Y. Yu, S. Grandi |
| 2021 |
Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases
10.1136/bmj.n2182
Authors: Y. Vinogradova, T. Dening, J. Hippisley-Cox, L. Taylor, M. Moore, C. Coupland |
| 2021 |
The use of mono- and combination drug therapy in men and women with lower urinary tract symptoms (LUTS) in the UK: a retrospective observational study
10.1186/s12894-021-00881-w
Authors: M. Ali, M. Landeira, P. Covernton, N. Choudhury, A. Jaggi, F. Fatoye, R. van Maanen |
| 2021 |
Use of prescribing safety quality improvement reports in UK general practices: a qualitative assessment
10.1186/s12913-021-06417-0
Authors: N. Khan, H. Booth, P. Myles, D. Mullett, A. Gallagher, C. Evans, N. Thomas, J. Valentine |
| 2021 |
Using Bayesian Networks to identify musculoskeletal symptoms influencing the risk of developing Psoriatic Arthritis in people with psoriasis
10.1093/rheumatology/keab310
Authors: A. Green, W. Tillett, N. McHugh, T. Smith |
| 2021 |
Using electronic health records to inform trial feasibility in a rare autoimmune blistering skin disease in England
10.1186/s12874-021-01212-1
Authors: M. Persson, K. Harman, K. Thomas, J. Chalmers, Y. Vinogradova, S. Langan, J. Hippisley-Cox, S. Gran |
| 2021 |
Utilisation and Safety of Polyethylene Glycol 3350 with Electrolytes in Children Under 2 Years: A Retrospective Cohort
10.1097/mpg.0000000000003074
Authors: D. Roy, F. Akriche, B. Amlani, S. Shakir |
| 2021 |
Utilization and long-term persistence of direct oral anticoagulants among patients with non-valvular atrial fibrillation and liver disease
10.1111/bcp.15046
Authors: A. Douros, Y. Cui, R. Platt, K. Filion, G. Sebastiani, C. Renoux |
| 2021 |
The Utilization and Safety of Umeclidinium and Umeclidinium/Vilanterol in UK Primary Care: A Retrospective Cohort Study
10.2147/copd.s291931
Authors: G. Requena, D. Dedman, J. Quint, R. Ghosh, R. Williams, J. Pimenta |
| 2021 |
Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study
10.1186/s12913-021-06762-0
Authors: L. Lix, S. Sobhan, A. St-Jean, J. Daigle, A. Fisher, O. H. Y. Yu, S. Dell'Aniello, N. Hu, S. Bugden, B. Shah, P. Ronksley, S. Alessi-Severini, A. Douros, P. Ernst, K. Filion |
| 2021 |
Validity of bariatric surgery codes in the UK Clinical Practice Research Datalink (CPRD) GOLD compared with Hospital Episodes Statistics
10.1002/pds.5221
Authors: T. Burkard, M. Rauch, S. Jick, C. Meier |
| 2021 |
Vertebral fracture as a risk factor for self-harm: a retrospective cohort study
10.1186/s12891-021-04631-9
Authors: J. Prior, F. Crawford-Manning, R. Whittle, A. Abdul-Sultan, C. Chew-Graham, S. Muller, T. Shepherd, A. Sumathipala, C. Mallen, Z. Paskins |
| 2021 |
Weight change, cardio-metabolic risk factors and cardiovascular incidence in people with serious mental illness: protocol of a population-based cohort study in the UK from 1998 to 2020
10.1136/bmjopen-2021-053427
Authors: C. Lee, F. Waite, M. Smith, M. Gao, C. Bankhead, P. Aveyard, C. Piernas |
| 2021 |
wEight chanGes, caRdio-mEtabolic risks and morTality in patients with hyperthyroidism (EGRET): a protocol for a CPRD-HES linked cohort study
10.1136/bmjopen-2021-055219
Authors: B. Torlinska, J. Hazlehurst, K. Nirantharakumar, G. Thomas, J. Priestley, S. Finnikin, P. Saunders, K. Abrams, K. Boelaert |
| 2021 |
Weight loss and risk reduction of obesity-related outcomes in 0.5 million people: evidence from a UK primary care database
10.1038/s41366-021-00788-4
Authors: C. Haase, S. Lopes, A. Olsen, A. Satylganova, V. Schnecke, P. McEwan |
| 2021 |
What is the incidence of methotrexate or leflunomide discontinuation related to cytopenia, liver enzyme elevation or kidney function decline?
10.1093/rheumatology/keab254
Authors: G. Nakafero, M. Grainge, T. Card, C. Mallen, W. Zhang, M. Doherty, M. Taal, G. Aithal, A. Abhishek |
| 2021 |
Women with Polycystic Ovary Syndrome have an increased risk of major cardiovascular events: a population study
10.1210/clinem/dgab392
Authors: T. Berni, C. Morgan, D. Rees |
| 2021 |
Younger people with rheumatoid arthritis are at increased risk of fracture even before age 50 years: a population-based cohort study
10.1007/s00198-021-05862-1
Authors: J. Erwin, D. Enki, A. Woolf |
| 2021 |
β-blocker prescription is associated with lower cumulative risk of knee osteoarthritis and knee pain consultations in primary care: a propensity score matched cohort study
10.1093/rheumatology/keab234
Authors: G. Nakafero, M. Grainge, A. Valdes, N. Townsend, C. Mallen, W. Zhang, M. Doherty, M. Mamas, A. Abhishek |
