Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort ascending Title
09/11/2021 Impact of COVID-19 vaccination on preventing long COVID: a population-based cohort study using linked NHS data
05/11/2021 The management of gout in primary and secondary care in England and Wales: a descriptive study
02/11/2021 Determining patients at risk of first Chronic Obstructive Pulmonary Disease (COPD) exacerbation in UK Global Initiative for Chronic Obstructive Lung Disease (GOLD) A and B Chronic Obstructive Pulmonary Disease (COPD) patients
02/11/2021 Quantification of potential undiagnosed Pulmonary Arterial Hypertension (PAH) patients among patients with chronic respiratory disorders and PAH-related cardiovascular conditions through machine learning models in the UK CPRD-HES databases
01/11/2021 Intimate partner violence, parental substance misuse and the mental health of parents & children - a retrospective open birth cohort
28/10/2021 Investigating the applicability of regression discontinuity in electronic health record for assessing the effectiveness of prostate-specific antigen screening for the prevention of prostate cancer
26/10/2021 The impact of the use of immunotherapy and risk of type I diabetes mellitus (TIDM) and other immune related adverse events: a population-based observational cohort study
26/10/2021 Bleeding events and adverse reactions in UK patients with non-valvular atrial fibrillation (NVAF) treated with edoxaban
25/10/2021 People living with diabetes and intermediate hyperglycaemia: risk of infections and effects of average level and variability of glycated haemoglobin (HbA1c) on this risk, in people from different ethnic groups
25/10/2021 What biopsychosocial factors are associated with abortions in primary care in Britain? A case control study comparing women aged 13 to 54 who had abortions compared with those who did not.
18/10/2021 Falling through the cracks: patterns of care for people with markedly elevated blood pressure seen in English primary care
14/10/2021 Examining patterns and clusters of comorbidities in people with psoriasis
14/10/2021 Estimated prevalence of multiple long term conditions
11/10/2021 Influenza and pneumococcal vaccination in adults with common inflammatory conditions treated with immune suppressing drugs: a study of vaccine uptake, clinical effectiveness and vaccine safety.
10/10/2021 Atherosclerosis following Deep Vein Thrombosis (ADVenT) study
07/10/2021 The effectiveness of faster aspart insulin versus other bolus insulins on glycaemic control in a real-world setting
07/10/2021 Comparison of effectiveness and safety of direct oral anticoagulant versus low molecular weight heparin treatment for active cancer-associated venous thromboembolism
07/10/2021 The safety of antipsychotic drugs in children and youth with attention deficit and hyperactivity disorder
07/10/2021 Aclidinium Bromide Post-Authorization Safety Study (PASS) to Evaluate the Risk of Cardiovascular Endpoints: Arrhythmias
04/10/2021 Retrospective cohort study assessing medication coverage in prostate cancer patients prescribed Luteinizing Hormone Releasing Hormone agonists (LHRH).