Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
28/11/2023	Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
28/11/2023	Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
24/11/2023	The treatment pathway for Atrial Fibrillation from diagnosis to ablation; including the influence of socioeconomic factors on access to ablation in England
23/11/2023	Clinical course, outcomes and risk factors of myocarditis and pericarditis following administration of the Moderna Spikevax COVID-19 vaccine (Elasomeran (mRNA-1273))
23/11/2023	Health outcomes of children with rare or complex diseases and their families: a descriptive longitudinal cohort study
23/11/2023	Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
23/11/2023	Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
22/11/2023	Health inequalities in People with seveRe mental Illnesses: Impact of antipsychOtic tReatments and social Inequalities on long Term phYsical health (PRIORITY).
22/11/2023	Association between COVID-19 and new onset of diabetes
20/11/2023	Exploring inequalities in diagnoses and outcomes of gynaecological cancers in England
17/11/2023	Suicide risk assessment in primary care attenders using big data from general practice
17/11/2023	Risk of suicide attempt in patients prescribed leukotriene receptor antagonists (LTRAs) and inhaled corticosteroids (ICS): a self-controlled case series study
17/11/2023	Clinical Management and Outcomes in Prostate Cancer: Observational, Population-Based Standing Cohort Study in England
15/11/2023	Prediction risk models for Cardiovascular disease for adults with asthma in England
15/11/2023	External validation of a lifetime major bleeding risk model in cohort patients with established cardiovascular disease and lifetime effect of intensified antithrombotic treatment
15/11/2023	The association between psoriasis and dementia: a population-based matched cohort study
15/11/2023	Advantages and Disadvantages using Different Marginal Structural Models Interval Durations in Pharmacoepidemiology
15/11/2023	The safety of beta-blockers in Chronic Obstructive Pulmonary Disease (COPD): A prevalent new-user cohort study
15/11/2023	Early identification of the association between rofecoxib and cardiovascular adverse events using real-world data from the UK: a case-control and case-crossover design
13/11/2023	Determining clusters of multiple long-term health conditions in patients undergoing surgery