Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Approved studies using CPRD Data

Date of Approval	Title
03/09/2021	UKPREG: UKPREGnancy study - a longitudinal international registry-based cohort study of pregnancy and heart disease
02/09/2021	Dose distributions of the injectable glucagon-like peptide-1 receptor agonists dulaglutide and semaglutide in patients with type 2 diabetes in UK primary care
02/09/2021	How many UK adults developed kidney failure since the year 2000? What treatments did they receive and what were their health outcomes?
26/08/2021	Clinical and economic burden of illness of catheter users in the UK
26/08/2021	Evaluating the performance of cutting-edge statistical methods in reducing confounding bias using plasmode simulations of electronic health record data
26/08/2021	Characterization of ezetimibe use in the United Kingdom: a retrospective database study
26/08/2021	Parkinson's Disease in minority ethnic groups: understanding phenotypical traits and differences in outcomes to inform pathways of care
26/08/2021	Evaluating treatment patterns of venous thromboembolism patients in primary care
26/08/2021	Analysis of the Clinical Practice Research Datalink (CPRD Gold + Aurum) and Hospital Episode Statistics (HES) to provide real world evidence on disease progression and the burden of uncomplicated urinary tract infection (uUTI)
26/08/2021	Association between degree of weight loss and reduction in risk of developing obesity related complications in adults living with obesity
26/08/2021	Clinical outcomes from robotic colorectal surgery in England: a national study using routinely collected data
26/08/2021	COVID-19 and incidence of venous thromboembolism (VTE) in the UK general population
17/08/2021	The Impact of COVID-19 on care for UK patients with chronic obstructive pulmonary disease (COPD) and patients with asthma
16/08/2021	The Impact of COVID-19 on care for UK patients with chronic obstructive pulmonary disease (COPD) and patients with asthma
11/08/2021	Assessing the clinical and economic burden among patients with Clostridium Difficile Infection and recurrent Clostridium Difficile Infections: A real-world evidence study
09/08/2021	Respiratory infection related cardiovascular disease: a prognostic modelling and causal inference study
05/08/2021	Concomitant use of biphasic insulin aspart and glucagon-like peptide-1 receptor agonist compared to modern basal insulin combined with glucagon-like peptide-1 receptor agonist: effect on glycaemic control in type 2 diabetes patients
02/08/2021	Differences in morbidity and mortality in men and women with chronic obstructive pulmonary disease and peripheral arterial disease
02/08/2021	Epidemiology and healthcare resource utilisation associated with Duchenne muscular dystrophy
29/07/2021	Determining treatment pathways, healthcare resource usage, and associated costs of patients with Myasthenia Gravis in England