Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Approved studies using CPRD Data

Date of Approval Sort ascending Title
22/09/2021 Multimorbidity between chronic diseases in the ageing populations
22/09/2021 Characterising the risk of malignancy in patients with atopic dermatitis prescribed immune suppressive medications
22/09/2021 Use of machine learning to improve the prediction of 10-years Cardiovascular Disease risk using data from Electronic Health Records
19/09/2021 Effects of the COVID-19 pandemic on primary care recorded anxiety and depression, and psychotropic prescribing.
19/09/2021 Understanding the contribution of influenza vaccines to antibiotic prescribing in the UK population: A longitudinal analysis
19/09/2021 Statin Treatment Options during vaccination against inFLUenza (STOPFlu) : a observational study of the interaction between statins and influenza vaccination
19/09/2021 Prevalence of poorly controlled asthma and factors associated with specialist referral in those with poorly controlled asthma in a paediatric asthma population.
19/09/2021 Early warning score for Autism Spectrum Disorder using real-world data
16/09/2021 Comparative effectiveness of second line glucose lowering therapies on preserving renal function in patients with type 2 diabetes
16/09/2021 Characterising surgery for wrist arthritis and its outcomes
15/09/2021 Describing causes of mortality in different subpopulations of people with Chronic Obstructive Pulmonary Disease and determining factors that may be associated with specific causes of death
15/09/2021 Cohort monitoring of Adverse Events of Special Interest and COVID-19 diagnoses prior to and after COVID-19 vaccination
15/09/2021 Non-invasive tests as prognostic biomarkers of liver events, cardiovascular events and all-cause mortality in individuals with obesity and or type 2 diabetes living in the United Kingdom: a longitudinal cohort study
09/09/2021 Healthcare resources utilisation and associated costs of adult Attention deficit hyperactivity disorder in England: A retrospective database study
09/09/2021 Predicting Psoriatic Arthritis (PREDIPSA) - Dynamic modelling of primary care health-records for earlier diagnosis of psoriatic arthritis: a population-based study
09/09/2021 Pregnancy induced hypertension, gestational diabetes, and the risk of chronic kidney disease: A population-based study using the Clinical Practice Research Datalink.
09/09/2021 Descriptive analysis of trends in health care use in England by ethnicity and deprivation over the austerity period culminating in the COVID-19 pandemic
05/09/2021 Comparative effectiveness of combination therapies on mortality in chronic obstructive pulmonary disease (COPD)
05/09/2021 The impact of painful musculoskeletal conditions on outcomes of dementia
05/09/2021 Impact of prompt versus delayed initiation of single-inhaler triple therapy among patients with Chronic Obstructive Pulmonary Disease in England in real-world primary and secondary care settings