Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
29/03/2017	Evaluation of the impact of glucose-lowering treatment with pioglitazone on stroke outcomes
29/03/2017	Nitrates, 5-alpha-reductase inhibitors and hormone replacement therapy and the risk of gastrointestinal cancers.
29/03/2017	Management of patients with Non-Valvular Atrial Fibrillation following a first clinically relevant bleed whilst being treated with an Oral Anticoagulant English clinical practice: a cohort study based on CPRD-Hospital Episode Statistics data
29/03/2017	Primary and secondary healthcare contacts in children born preterm and their households
29/03/2017	Acute exacerbations of chronic obstructive pulmonary disease: Clinical history and effects on rate of recurrent events and risk of death
29/03/2017	The relationship between non-valvular atrial fibrillation and dementia
27/03/2017	Ovulation-Inducing Fertility Treatments and the Long-Term Risk of Breast Cancer
27/03/2017	Oral anticoagulants for atrial fibrillation and the risk of acute kidney injury
27/03/2017	Are primary care consultations about insomnia associated with later dementia?
13/03/2017	The diagnostic utility of inflammatory markers in primary care: a prospective cohort study.
13/03/2017	Hypoglycaemia and serious adverse events in older people living with diabetes and dementia – a population-based cohort study
12/03/2017	Accounting for multimorbidity, competing risk and direct treatment disutility in risk prediction tools for the primary prevention of cardiovascular disease and fracture.
10/03/2017	Matched population-based cohort study determining the incidence and risk of cardiovascular outcomes for patients with familial hypercholesterolaemia
10/03/2017	The risk of fractures in new users of statins: A propensity-score matched sequential cohort study
08/03/2017	Exploration of long term cardiovascular outcomes following pregnancy complicated by hypertensive disorders or pregnancy
08/03/2017	Pattern of use of Direct Oral AntiCoagulant (DOAC) in Non-Valvular Atrial Fibrillation (NVAF) patients in UK general practices
08/03/2017	Statin prescribing and depression after incident stroke
06/03/2017	Canagliflozin in patients with type 2 diabetes: understanding the real world evidence: CAPTURE study 'Capture - treatment patterns in EMEA'
05/03/2017	Stratified 30 day excess risks of emergency hospital admissions and death following gastrointestinal endoscopy
01/03/2017	Burden of disease in patients with COPD and high blood eosinophil counts