Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
18/05/2017	Assessing the risk of infection among babies born to mothers with Systemic Lupus Erythematosus; a study of the first two years of life.
16/05/2017	Association between glycated hemoglobin (HbA1c), weight and hypoglycemia to treatment choice and medication adherence in Type 2 Diabetes Mellitus (T2DM)
16/05/2017	Comorbidity as a predictor of referral to, and outcome from, joint replacement surgery in primary care patients with newly diagnosed arthritis: a population-based cohort study
16/05/2017	Ocular morbidity associated with Giant Cell Arteritis and Polymyalgia Rheumatica: a controlled cohort study using the UK Clinical Practice Research Datalink
15/05/2017	Loop diuretic use and risk of adverse outcomes among patients with atrial fibrillation
12/05/2017	Life-Limiting Conditions in Children and Young People: Prevalence and GP involvement
12/05/2017	Uptake and effectiveness of the seasonal trivalent influenza vaccine in autoimmune inflammatory rheumatic disease patients receiving corticosteroids and disease modifying anti-rheumatic drugs
11/05/2017	Development and validation of multimorbidity scores for health services outcomes
11/05/2017	Comorbidities and Medication Use in Patients Diagnosed with Multiple Sclerosis Compared to Patients Without Multiple Sclerosis
10/05/2017	Characterization of Chronic Obstructive Pulmonary Disease (COPD) patients initiating inhaled triple therapy in the United Kingdom
09/05/2017	The risk of depression and anxiety in adults diagnosed with vitiligo compared to the general population, in the UK
09/05/2017	Parkinson's disease and the risk of epileptic seizures - cohort study with nested case-control analysis
09/05/2017	Assessment of the scientific feasibility of utilizing the CPRD to conduct a randomized point of care trial in COPD patients
09/05/2017	Description of Palliative Care Referral Among Patients With COPD in the UK
02/05/2017	Incretin-based Drugs and the Risk of Adverse Renal Outcomes
02/05/2017	Predicting prostate cancer progression: Associations between routine primary care data and prostate cancer outcomes.
27/04/2017	Incidence of liver failure and non-viral hepatitis in Multiple Sclerosis (MS) patients and in the general population - a study using the CPRD
27/04/2017	Risk of developing chronic obstructive pulmonary disease or lung cancer in smokers taking enzyme-inducing antiepileptic drugs
27/04/2017	Blood eosinophilia as a biomarker for response to inhaled corticosteroids in COPD.
27/04/2017	Interruption of Renin-Angiotensin-Aldosterone System Inhibition Treatment and Associations with Adverse Outcomes