Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
01/02/2017	Assessment of the rate of vaccine co-administrations with Bexsero
01/02/2017	Association between Rheumatoid Arthritis and comorbidities: a combined retrospective case-control and prospective cohort study.
01/02/2017	Investigating the impact of BMI of patient with type 2 diabetes on length and cost of hospital stay for complications related to diabetes.
01/02/2017	Unintended effects of zaleplon, zolpidem, zopiclone (Z-drugs) use for sleep disturbance in people with dementia
01/02/2017	The risk of cardiovascular diseases among survivors of site-specific adult cancers: a matched cohort study
01/02/2017	The Risks of Mortality, Cardiovascular Events, and Diabetes Associated With Statin Use In Patients With Rheumatoid Arthritis
26/01/2017	Clinical burden of illness and healthcare resource utilisation among COPD patients stratified by their moderate-severe exacerbation frequency, inhaled triple maintenance treatment status and blood eosinophil levels
26/01/2017	Developing Personalised Renal Function Monitoring for Heart Failure Patients
26/01/2017	Investigation of the comparative safety of opioid drugs within CPRD- part of the International Pharmacosurveillance Study
23/01/2017	Derivation and validation of statistical models to forecast acute death and longer term survival in people with cirrhosis
23/01/2017	RAASi use patterns following incident hyperkalemia in England
23/01/2017	Effects of changing pre-eclampsia management on acute renal failure and other maternal and perinatal outcomes in the United Kingdom: An interrupted time-series analysis
23/01/2017	Utilising electronic health records to investigate the association of liver function tests with incidence and outcomes of gastrointestinal disease and malignancy
23/01/2017	Associations between absolute value, and change in value, of albumin-creatinine ratio and major adverse health outcomes
23/01/2017	The Use of Angiotensin Converting Enzyme Inhibitors and the Risk of Lung Cancer
19/01/2017	Determining incidence of patient safety events in primary care using patient record data
18/01/2017	Potential benefits of antithrombotic treatment in reducing risk of subsequent cardiovascular events among patients with a prior myocardial infarction in England
16/01/2017	Use of hormone replacement therapy and risk of breast cancer
13/01/2017	The incidence and mortality of complicated diverticular disease and associated outcomes following intervention
13/01/2017	Characterising the primary care population with frailty to better stratify and target healthcare interventions