Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
27/09/2019	Patient pathway and therapeutic inertia in newly diagnosed T2DM patients with multimorbidity
27/09/2019	The Impact of Exacerbation Burden on Lung Function Trajectory in a Broad Asthma Population
26/09/2019	What care is currently provided in the NHS for people with coeliac disease and what does it cost?
26/09/2019	Treatment, Complications, and Costs in Clavicle Fracture and Acromioclavicular Dislocation
26/09/2019	The Prevalence of Clostridioides difficile Infections (CDIs) in Age- and Comorbidity-Based Risk Groups in England: The PERFECT Study
25/09/2019	Antibiotic use and risk of glioma
23/09/2019	Morbidity, mortality and quality of healthcare for people who use heroin and crack cocaine: a cohort study based on linked primary care data in England
19/09/2019	Ageing Inequalities: A cohort study to investigate delay in diagnosis and inequalities in treatment of dementia and cancer in the elderly
19/09/2019	Effectiveness of BISOprolol on high blood PRESSure versus other ?-blockers, and versus other anti-hypertensive classes. A cohort study in the UK Clinical Practice Research Datalink (CPRD)
19/09/2019	Use of non-interventional data for determining the real-world effectiveness of anticoagulation medication for stroke prevention in a clinical trial analogous population
19/09/2019	Burden of pneumococcal disease and pneumococcal vaccination in adults with underlying medical conditions in the UK
19/09/2019	Understanding the health care needs of people with common mental disorder and additional long-term conditions
12/09/2019	Incidence of adverse effects related with long-term use of paracetamol: a propensity score matched cohort study.
11/09/2019	Hypertensive disorders of pregnancy and risk of cardiovascular disease in women: electronic cohort study in primary care
11/09/2019	Data analysis of the current treatments for major depressive disorder and treatment resistant depression in Scotland
09/09/2019	Cancer risk in transgender individuals
06/09/2019	Utilization of routinely performed diagnostic tests in primary care
06/09/2019	Prevalence, management and prognosis of individuals with resolved asthma.
05/09/2019	Evaluation of the survival, treatment pathways and liver disease outcomes of patients with liver disease and their progression to cirrhosis and hepatic encephalopathy: a non-interventional study using primary and secondary healthcare data from the UK
05/09/2019	A retrospective, non-interventional, descriptive study to define the rate of adverse events in subjects with various stages of chronic kidney disease