Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
09/12/2019	Long-term survival following invasive pneumococcal disease: a matched cohort study
09/12/2019	Does the transition from paediatric to adult healthcare lead to increased healthcare usage for young people with a life limiting condition? A quasi-experimental longitudinal cohort study
09/12/2019	Risk factors in prosthetic joint replacement infections
06/12/2019	The prevalence of liver enzyme and function testing in UK primary care
06/12/2019	National and local perspectives in venous leg ulceration: estimating prevalence and mapping referral pathways
06/12/2019	Characterization of mild, moderate and severe asthma patients based on the GINA guidelines in the UK CPRD database
06/12/2019	Statins and the development of type-2 diabetes: assessing the benefit-risk ratio for patients with low risk of cardiovascular disease
05/12/2019	Contemporary epidemiology of coeliac disease, dermatitis herpetiformis, Crohn’s disease and ulcerative colitis in the United Kingdom
04/12/2019	The relative vaccine effectiveness of current and emerging influenza vaccines in people aged 65 years and above: a nationwide cohort study
04/12/2019	Primary Care Treatment Pathways in Parkinson’s Disease in the UK
02/12/2019	Sickle Cell Anaemia and risk of cardiovascular disease: a UK population study
28/11/2019	Infectious burden and the risk of incident dementia: a nested case-control study
27/11/2019	Spillover effects of removing indicators from the Quality and Outcomes Framework
27/11/2019	Incidence of adhesive capsulitis in primary care in the UK, and associated inflammatory conditions
27/11/2019	Drug utilisation studies using CPRD mapped to the OMOP Common Data Model: a proof of concept study assessing respiratory drug use in patients with asthma or COPD
27/11/2019	What is the risk of decompensation and mortality after non-hepatic gastrointestinal surgery in patients with alcoholic liver disease?
27/11/2019	Identifying and describing the burden of morbidity following major surgery: a linked electronic health records cohort study
27/11/2019	Retrospective study on Multi-vessel disease and prevalence of major adverse cardiovascular events: a CPRD-HES Study from 2008 to 2017 (The ReMoVe MACE Study)
27/11/2019	The economic and clinical burden of hyperkalaemia in England: a retrospective cohort study using the Clinical Practice Research Datalink
27/11/2019	Cancer risk in patients with cirrhosis