Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
15/01/2019	Comparing the characteristics between non-valvular atrial fibrillation patients who are treated or untreated with oral anticoagulants
14/01/2019	Epidemiology of Valvular Heart Disease in Epilepsy Patients
10/01/2019	Mapping the opportunities for earlier diagnosis and characterising the management costs of psoriasis and impact of key co-morbidities
10/01/2019	REPEAT: Study 21 - Replication of “Managing glycaemia in older people with type 2 diabetes: A retrospective, primary care-based cohort study, with economic assessment of patient outcomes”
10/01/2019	The influence of the number of concomitant drugs used, on the safety and efficacy of NOACs compared to warfarin in patients with atrial fibrillation treated in routine care
10/01/2019	Does aspirin affect the risk of cardiovascular events after pneumonia?
10/01/2019	Are beta blockers beneficial or harmful in obstructive sleep apnoea?
10/01/2019	Understanding the Relationship between Multimorbidity in Later Life, Use of Health Services and Costs of Health Care (MuSeCol)
10/01/2019	Guideline discordant diagnostic care: when do primary care referrals not reflect guidelines for suspected cancer?
02/01/2019	BurDeN Study: Incidence and Burden of Disease from Shingles and Post-Herpetic Neuralgia in the over 80 year olds in the UK
02/01/2019	An epidemiological study to compare adverse events associated with different formulations of latanoprost
21/12/2018	Clinical features of giant cell arteritis (GCA): An observational study using linked electronic primary and secondary care medical records
21/12/2018	The pattern of incident fractures in patients with diabetes mellitus compared to matched controls
21/12/2018	Defining different recovery trajectories following acute infections as a measure of frailty
19/12/2018	A study using Observational Health Data Sciences and Informatics tools to characterize treatment pathways for stroke prevention in Atrial Fibrillation across diverse population settings (TxPath-AF)
19/12/2018	A personalized dynamic blood pressure control plan for patients with hypertension to maximize the delay of cardiovascular events
19/12/2018	Identifying risk factors associated with having a stroke following an acute exacerbation of COPD (AECOPD)
19/12/2018	Withdrawal of historical inhaled corticosteroids in primary care using electronic records
19/12/2018	Understanding the predictive values of symptoms, prescriptions, and investigation patterns for cancer and non-neoplastic disease in primary care consultees
19/12/2018	The progression of key clinical parameters in adult diabetes patients (selected type 1 and type 2 diabetes sub-population): a retrospective cohort analysis to support economic modelling activities in a UK-specific context