Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
11/09/2018	Uptake of pneumococcal and zoster vaccines by clinical risk groups in England
10/09/2018	Mortality trends in people with and without type 2 diabetes in UK: a CPRD observational study
10/09/2018	Sodium-glucose co-transporter 2 inhibitors and the risk of fractures in patients with type 2 diabetes
10/09/2018	Cardiovascular risk and kidney disease progression in chronic kidney disease
10/09/2018	Initiation of Combination Therapy in Type 2 Diabetes Patients with high HbA1c at diagnosis
10/09/2018	Characterization of acute coronary syndrome patients that switch from dual antiplatelet therapy to monotherapy with clopidogrel or aspirin
10/09/2018	Referral rates of severe asthma patients to asthma specialists in the UK and the impact on healthcare use
04/09/2018	Association of early detection of non-diabetic hyperglycaemia and clinical outcomes in England: a retrospective cohort study
29/08/2018	General practice consulting behaviours prior to atrial fibrillation diagnosis: an investigation of potential opportunities for targeted screening
29/08/2018	A study to evaluate growth characteristics and burden of illness in patients with achondroplasia
29/08/2018	Age at onset of multiple cardiovascular disease conditions: differences in ethnic subgroups by diabetes status
29/08/2018	The relationship between partner bereavement and being diagnosed with dementia
29/08/2018	The burden of incontinence of urine associated with prostate cancer treatment: documenting the prevalence and highlighting the difference between prostate cancer treatment modalities
28/08/2018	Developing and validating a measure of inappropriate polypharmacy
24/08/2018	Evaluation of natural history and health care resource utilisation of patients with monocloncal gammopathy of unknown significance and myeloma bone disease
22/08/2018	Prediction of anticoagulation control and associated health economic outcomes in patients with atrial fibrillation (AF) managed on warfarin
22/08/2018	The role of CA125 in the detection of ovarian cancer in symptomatic primary care patients
22/08/2018	Testosterone replacement therapy and the risk of prostate cancer in men with age-related hypogonadism
22/08/2018	Assessing the Burden of Allergy Management in England
20/08/2018	Investigating associations between environmental factors and exacerbations of COPD and asthma