Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
03/08/2017	Alzheimer's treatment and the risk of serious adverse events
03/08/2017	Identification of high cost patients in primary and secondary care and an analysis of their utilisation patterns, and social and demographic characteristics.
03/08/2017	MENTAL COMORBIDITIES AND USE OF PSYCHOTROPIC MEDICATIONS IN PATIENTS WITH AUTISM SPECTRUM DISORDERS IN THE UNITED KINGDOM
03/08/2017	Medication Use and Pregnancy Outcomes in Women with Systemic Lupus Erythematosus within the Clinical Practice Research Datalink
01/08/2017	Clinical profile of pre-defined asthma phenotypes in a large cohort of UK primary care patients (CPRD).
27/07/2017	An evaluation of the epidemiology, burden of illness and financial costs of healthcare services for people with peanut allergy in the United Kingdom.
26/07/2017	Treatment of acute lower respiratory tract infections in patients with and without asthma
26/07/2017	The routine use of electronic healthcare record data to strengthen signal evaluation and early pharmacovigilance decision making in UK medicines regulation
25/07/2017	Healthcare resource utilisation and costs of major bleeding events and ischemic stroke among non-valvular atrial fibrillations patients in the UK
25/07/2017	Epilepsy in the elderly: optimising care for a growing, yet critically under-recognised, population
25/07/2017	Seizure frequency and resource utilisation associated with initiation of perampanel, eslicarbazepine and rufinamide in patients with epilepsy
25/07/2017	Investigating the impact of the introduction of a named GP assigned to patients 75 and over on their continuity of care and emergency hospital admission
25/07/2017	Characterising the risk of major bleeding in patients with Non-Valvular Atrial Fibrillation: non-interventional study of patients taking Direct Oral Anticoagulants in the EU
25/07/2017	Effects of financially-induced inhaler switching on the risk of an acute exacerbation in patients with asthma or chronic obstructive pulmonary disease (COPD): a self-controlled case series
24/07/2017	Eligibility for blood pressure lowering treatment and subsequent cardiovascular disease burden under four different treatment approaches: a cohort study
20/07/2017	Impact of the definition of osteoarthritis and the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink.
18/07/2017	The association between glycated haemoglobin (HbA1c), glycaemia and chronic kidney disease with or without anaemia.
18/07/2017	Multi-database imputation to adjust for confounders within distributed data drug safety networks – a methodological study using real-world data from the UK Clinical Practice Research Datalink
18/07/2017	Can CHA2DS2-VASc score be used to identify patients under 65 years old at high risk of atrial fibrillation?
18/07/2017	Steroid Use and the risk of Venous Thromboembolism in Asthma Patients