Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
18/07/2017	Incidence of major bleeding events and ischaemic stroke among non-valvular atrial fibrillation patients in the UK
18/07/2017	Systemic sclerosis in the UK: what is the disease burden and are there associations with other serious health outcomes?
14/07/2017	Quantifying variation in UK primary care test use: A 15 year retrospective CPRD analysis of temporal and geographical variation in test use.
14/07/2017	Impact of methods for measuring the prevalence and incidence of chronic disease in the UK population based on electronic medical record (EMR) data
14/07/2017	The association between chronic kidney disease and tuberculosis; a comparative cohort study in England
12/07/2017	Multinational Observational Database Study on Imminent Osteoporotic Fracture Risk
12/07/2017	Renal function and prescribing patterns of DPP-4 inhibitors in the UK: The extent of regional variation, dose adjustment and therapy switching.
12/07/2017	Prevalence and incidence of dementia diagnosis in patients with and without chronic kidney disease in the UK
12/07/2017	Meningococcal B vaccine: incidence of convulsion following vaccination and compliance with timing of vaccine doses in the UK
12/07/2017	The associations between inFLAmmatory and non-inflammatory oral Mucosal diseases and hEad and Neck squamous Cell carcinOma (FLAMENCO).
12/07/2017	Understanding clinical and healthcare predictors of diagnostic timeliness in patients with suspected cancer
12/07/2017	Cancer-related Mortality in Type 2 Diabetes: A Population-Based Cohort Study Quantifying Relationships with Body Mass Index using Linked Electronic Health Records
07/07/2017	Incidence and prevalence of nontuberculous mycobacterial pulmonary disease (NTMPD) in the UK since 2004
06/07/2017	Count of hospital admissions due to Influenza and Respiratory Syncytial Virus by year of birth and severity, England, 2010-2016
06/07/2017	Persistence and compliance to anti-osteoporosis medications in the United Kingdom
05/07/2017	Effectiveness of proton pump inhibitors in idiopathic pulmonary fibrosis
03/07/2017	Comparison of Outcomes for Patients Hospitalised with Decompensated Heart Failure in the UK and Japan
30/06/2017	The Effects of Adherence and Treatment Intensity on Cardiovascular Outcomes in Patients with Atherosclerosis or Other Cardiovascular Risk Factors Treated with Statins and/or Ezetimibe: A Cohort Study in the United Kingdom
30/06/2017	Post-authorization Safety Study: Evaluation of Cardiovascular Events in Users of Mirabegron and Other Treatments for Overactive Bladder in the CPRD
28/06/2017	Determining the annual proportion of women who could receive an opportunistic assessment of familial breast cancer in primary care to inform an economic model