Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
23/08/2017	Use of anti-Alzheimer's disease treatments among individuals with mild cognitive impairment
22/08/2017	Association between antineoplastic therapies and venous thromboembolism in patients with active cancer
18/08/2017	Cardiovascular Disease Risk Prediction Screening Using Electronic Health Records
18/08/2017	Estimating heterogeneous treatment effects from routinely collected health data: A case study on anticoagulant therapy for atrial fibrillation patients.
18/08/2017	Comparative effectiveness of combination therapies in COPD
18/08/2017	Predicting atrial fibrillation or atrial flutter (AF/F) using electronic patient health records in the United Kingdom
18/08/2017	Persistence and healthcare resource utilisation in non-valvular atrial fibrillation patients treated with oral anticoagulants in England
18/08/2017	Distance from glycaemic goal in patients with Type 2 Diabetes Mellitus in the UK
17/08/2017	Epidemiology of bleeding complications post-Acute Coronary Syndrome within the UK primary care setting
09/08/2017	Decline In lung function Among Patients with chronic obstructive Lung disease On maintenance therapy (DIAPLO)
08/08/2017	Adverse drug reactions in UK primary care consultations: a retrospective cohort study to evaluate impact on appointments, hospitalization, and treatment discontinuation
08/08/2017	Incidence and prevalence of autoimmune hepatitis in the UK. A population-based cohort study.
08/08/2017	Risk of colorectal adenoma after obesity surgery
08/08/2017	Restriction and comorbidity matching to control for confounding in a study of 5 alpha reductase Inhibitors (5ARIs) and risk of Venous Thromboembolism (VTE) in male Benign Prostatic Hyperplasia (BPH) patients.
08/08/2017	Trends in survival of older care home residents in England since 1995: a multi-cohort study
04/08/2017	Effectiveness of triple therapy versus dual bronchodilation in patients with chronic obstructive pulmonary disease
03/08/2017	Cardiovascular risk prediction in daily practice: are risk scores such as QRISK2 accurate enough to be used for individual patient care?
03/08/2017	Regional and patient variations in treatment pathways to access hip and knee replacement surgery, and the effects on surgical outcomes
03/08/2017	EMERALD: Exploring Mental Illness and Diabetes through a Longitudinal Data study
03/08/2017	Utilisation of antiepileptic medicines in girls and women of childbearing potential