Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
12/10/2017	Using electronic health records to identify patients at high risk of severe liver disease
12/10/2017	The impact of blood pressure thresholds on the risks of acute coronary syndrome (ACS) and stroke in non-cardiac surgery: a United Kingdom population-based cohort study
12/10/2017	Primary care prescriptions of nephrotoxic medications in children with a previous episode of acute kidney injury or with a diagnosis of chronic kidney disease
11/10/2017	The adverse effects of tramadol
09/10/2017	Investigating mortality risks up to and after the first presentation of cardiovascular disease: a cohort study using linked CPRD primary care, hospital admission and mortality data
09/10/2017	Estimation and characterisation of the potential COPD population for triple therapy combining long-acting muscarinic antagonist, long acting ?2-agonist and inhaled corticosteroid.
09/10/2017	Healthcare resource utilization among patients diagnosed with Systemic Sclerosis-associated Interstitial Lung Disease in the United Kingdom: An observational study using the Clinical Practice Research Datalink - INTERSTELLAR
06/10/2017	Treatment of venous thromboembolism in England: an observational cohort study using Clinical Practice Research Datalink, Hospital Episode Statistics and Office for National Statistics databases
06/10/2017	AChEIs and the Risk of Acute Ischemic Events and Bleeding in Patients with AD
06/10/2017	Improving statistical methods for estimating treatment effects from electronic health records in health economic evaluation.
05/10/2017	Derivation and validation of a clinical algorithm to predict patient cholesterol response to the initiation of statins and cardiovascular outcomes.
05/10/2017	Association of blood lipids, atherosclerosis and statins with post-stroke cognitive impairment
29/09/2017	Association between the prevalence of cardiovascular risk factors and new use of testosterone
29/09/2017	Cardiovascular Outcomes and Mortality in Cardio-Renal-Metabolic Disease Progression in Type 2 Diabetes Mellitus Patients within the United Kingdom
29/09/2017	Risk factors for biliary tract cancer in the United Kingdom Clinical Practice Research Datalink Database
29/09/2017	Epidemiology, outcomes, treatment patterns, and health resource utilization among English patients with coronary artery disease (CAD), heart failure (HF), and CAD/HF
29/09/2017	Developing a Clinical Decision Support Tool for the Early Diagnosis of Malignant Tumours of the Pancreas
29/09/2017	Drug Utilisation Patterns and Healthcare Resource Use in Patients With Neurogenic Bladder (NGB): A descriptive study using electronic health records from the UK
25/09/2017	The effect of renin-angiotensin system inhibitors on haemoglobin
22/09/2017	Utility and performance of prognostic algorithms for cardiovascular disease in type 2 diabetes patients.