Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
04/10/2022	Comparison of information on diagnosis and treatment of common chronic diseases in the Million Women Study cohort and in primary care data held by CPRD
29/09/2022	Natural history of B-cell malignancy
29/09/2022	The epidemiology of conditions listed in ICD-10 chapter XXII Codes for special purposes in the United Kingdom and the healthcare care cost and resource use associated with managing these conditions
29/09/2022	Integrated care pathway for stroke and cardiovascular outcomes: A population-based cohort study
28/09/2022	A cohort study of the prevalence of potentially inappropriate prescribing in middle aged adults and it's association with clinical outcomes, and healthcare utilisation
27/09/2022	Estimating inequality in alcohol-related liver disease burden by ethnicity and socioeconomic deprivation
26/09/2022	The impact of clinical roles fundable through the Additional Roles Reimbursement Scheme on the delivery of care and patient outcomes: a cohort study
23/09/2022	The effect of sex hormones on asthma: a population-cohort study
23/09/2022	The effect of diabetes medications on asthma attacks: a population-cohort study
23/09/2022	Cholesterol trajectories and cumulative effects of atherogenic factors on the lifetime risk of cardiovascular disease outcomes: A cohort study using UK primary and secondary care data
22/09/2022	Recovery following a hospitalisation with influenza infection using Clinical Practice Datalink (CPRD), linked to Hospital Episode Statistics.
22/09/2022	Characterizing and analyzing COVID-19 diagnosed participants and their outcomes, such as mortality and disease progression based on contributing factors including comorbidities
21/09/2022	Antifibrotics and mortality in patients with idiopathic pulmonary fibrosis: a population-based cohort study
20/09/2022	Frailty trajectories in patients taking statins: A propensity score-matched cohort study using UK primary care data
16/09/2022	Clinico-demographic characterisation and health care resource utilisation of chronic pain patients in the UK: A CPRD analysis
16/09/2022	Development and validation of cardiovascular disease (CVD) risk prediction model incorporating reproductive and pregnancy-related candidate predictors in women with a history of pregnancy
16/09/2022	Developing better understanding of physical and functional outcomes of chronic pain in people with mental health problems
15/09/2022	Comparative Effectiveness of Long-acting Insulins and Neutral Protamine Hagedorn (NPH) Insulin for the Prevention of Micro and Macrovascular Complications Among Patients with Type 1 Diabetes
14/09/2022	Development of multi-state model of UK stroke incidence and mortality, and thereby estimate the scope for future improvements in UK stroke mortality through better management of hypertension
13/09/2022	Advancing understanding of multi-morbidity in metabolic disease through innovation in statistical machine learning