Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
05/07/2022	The epidemiology of diseases of the ear and mastoid process in the United Kingdom and the healthcare care cost and resource use associated with managing these conditions
05/07/2022	Chronology of healthcare resource use and comorbidities in people with obstructive sleep apnoea and narcolepsy before and after diagnosis: a descriptive study
01/07/2022	Development of a prognostic score to predict effectiveness and cost-effectiveness of treatment in diabetes: a data-driven approach
29/06/2022	Concomitant use and interaction of selective serotonin reuptake inhibitors and oral anticoagulants and the risk of bleeding
29/06/2022	Use of oral anticoagulants and risk of incident diabetes among patients with atrial fibrillation
27/06/2022	A retrospective database analysis of the epidemiology, patient characteristics, treatment patterns, and resource utilisation in patients with prostate cancer in England: A real-world data study
27/06/2022	Redefining polypharmacy: A population-based longitudinal study using electronic medical records
27/06/2022	Investigating prescribing and diagnostic testing preferences in general practice
27/06/2022	Economic consequences of childhood excess weight: Secondary analyses of CPRD
27/06/2022	Within-episode repeat antibiotic prescribing in patients with respiratory tract infections: a population based cohort study
24/06/2022	Ethnic differences in depression and anxiety among adults with atopic eczema: a population-based matched cohort study.
24/06/2022	Improving first line treatment options for people newly diagnosed with psoriatic arthritis: a UK based cohort study.
24/06/2022	Examining the risk of adverse events in patients taking glucocorticoid therapy
24/06/2022	Treatment with antidiabetics and steroidal mineralocorticoid receptor antagonists in patients with type 2 diabetes and moderate to severe chronic kidney disease
22/06/2022	Investigating the healthcare resource utilisation of metastatic melanoma survivors treated with immunotherapies
22/06/2022	Trends in the Use of Combination Therapy as First-Line Treatment for Hypertension In UK Primary Care
21/06/2022	Incretin-based drugs and the risk of dementia among patients with type 2 diabetes
21/06/2022	Predicting the development of psoriatic arthritis in people with psoriasis: a UK based cohort study.
17/06/2022	Natural history and survival extrapolation of prevalent cancers
10/06/2022	Agreement of severe mental illness recording across English primary care and secondary mental health care.