Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
29/07/2022	Ethnic Disparities in Quality of Care Among Type 2 Diabetic Patients Before and During the COVID-19 Pandemic: A Before and After Study Using UK Electronic Health Records
29/07/2022	Does poor sleep mediate the association between moderate-to-severe eczema and major adverse cardiovascular outcomes?
22/07/2022	The health resource utilisation for people with thrombotic thrombocytopenic purpura (TTP) and a matched population without TTP as well as the estimated prevalence and annual incidence of TTP using primary and secondary care data.
22/07/2022	The association between pre-existing prediabetes and type 2 diabetes on breast cancer-related and overall mortality among women with breast cancer
20/07/2022	Factors associated with the altered likelihood of receiving bariatric surgery or weight loss pharmacotherapy within the UK: A CPRD study
18/07/2022	Risk of abnormal uterine bleeding associated with high-affinity compared with low-affinity serotonin and noradrenalin reuptake inhibitors
18/07/2022	Describing drug prescription pathways and prescription cascades for patients on anti dementia medications
14/07/2022	Antidiabetic drugs and risk of stroke: a nested case-control study
14/07/2022	Classification of Acute Kidney Injury phenotypes using unsupervised machine learning of electronic health records
14/07/2022	The impact of urban development on physical care and healthcare utilisation
14/07/2022	Patient characteristics, healthcare resource utilization and costs among patients with COVID-19 in England
14/07/2022	The impact of NHS England's Evidence Based Interventions programme on patient care and costs, using acute tonsillitis and Dupuytren's contracture as case studies.
12/07/2022	Data-driven approaches for detecting fast progressors to end-stage renal disease (ESRD) among all stage chronic kidney disease (CKD) patients powered by a large electronic-health record (EHR) dataset
12/07/2022	Investigating the effect of chronic obstructive pulmonary disease (COPD) status on all-cause and cause-specific morbidity and mortality trends in Type II diabetes patients: a cohort study using the CPRD Aurum.
12/07/2022	Understanding the prevalence of behavioural disorders amongst children and adolescents
12/07/2022	The economic cost of primary care utilisation due to Long COVID (post-COVID-19 condition) in non-hospitalised individuals; a retrospective cohort study using UK primary care data.
08/07/2022	A retrospective cohort study examining the epidemiology and clinical management of immune thrombocytopenic purpura in England
05/07/2022	Examining Ethnic Differences in Covid-19 and Post-Covid Syndrome Among People with Type II Diabetes in the UK
05/07/2022	Real-world study using CPRD primary care and linked data to identify and explore prostate cancer disease states and outcomes
05/07/2022	The trend of incidence and prevalence of Polycystic Ovary Syndrome and its associated health resource use and cost in the United Kingdom.