Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
10/06/2022	Real World Effects of Medications for Chronic Obstructive Pulmonary Disease
10/06/2022	Agreement of severe mental illness recording across English primary care and secondary mental health care.
09/06/2022	The epidemiology and healthcare resource utilisation associated with managing fragile X syndrome
08/06/2022	External validation of existing dementia prediction models on observational health data
08/06/2022	Weight loss and reproductive outcomes in women with overweight or obesity: a population-based cohort study using the UK clinical practice research datalink
08/06/2022	Evaluation of real-world effectiveness and safety of new diabetes drugs: a meta-analysis collaboration
01/06/2022	The Incidence and Prevalence of Eosinophilic Oesophagitis and diagnostic delays in CPRD AURUM.
01/06/2022	Trends and inequalities in statin use for the primary and secondary prevention of cardiovascular disease
30/05/2022	Resource use and survival evaluation using UK data from CPRD HES and NCRAS databases among patients with neuroendocrine tumours (NETs): A retrospective analysis
30/05/2022	REVEAL-UK: Real world Evidence in Vitiligo Employing dAtabase anaLyses in UK
30/05/2022	Investigation of life-expectancy and likelihood of shortened survival in a X-linked hypophosphataemia (XLH) population in England
27/05/2022	Liraglutide prescribing for weight management in the UK: a descriptive study using CPRD primary care databases
25/05/2022	Smoking cessation treatment provision in primary care in the UK - varenicline safety warnings and electronic cigarette monitoring
25/05/2022	The role of antibiotics in the aetiology of fibromyalgia
25/05/2022	Use of sodium glucose co-transporter-2 inhibitors and the risk of dementia
23/05/2022	Time to diagnosis of inflammatory bowel disease and its association with clinical outcomes: a retrospective cohort study in primary care
23/05/2022	Describing the prevalence and outcomes of patients taking therapeutic corticosteroids who present for major surgery
23/05/2022	Associations of severity of underlying health conditions, age-based eligibility criteria and hospital outpatient clinic attendance with seasonal influenza vaccination uptake in adults: a cohort study in England 2018-2021
23/05/2022	Association between preterm delivery and subsequent maternal risk of hypertension and type 2 diabetes mellitus in a United Kingdom population-based retrospective cohort study.
19/05/2022	Can we diagnose rare Antinuclear antibody (ANA)-associated autoimmune diseases earlier? A matched cohort study of ANA positive patients.